Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   GE021_RS03025 Genome accession   NZ_CP053792
Coordinates   587391..588101 (+) Length   236 a.a.
NCBI ID   WP_125074098.1    Uniprot ID   A0A3P5XNP4
Organism   Streptococcus canis strain HL_77_1     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 582391..593101
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE021_RS03000 (GE021_003000) dhaK 582666..583655 (+) 990 WP_125074093.1 dihydroxyacetone kinase subunit DhaK -
  GE021_RS03005 (GE021_003005) dhaL 583666..584241 (+) 576 WP_125074094.1 dihydroxyacetone kinase subunit DhaL -
  GE021_RS03010 (GE021_003010) dhaM 584241..584618 (+) 378 WP_125074095.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  GE021_RS03015 (GE021_003015) - 584629..585342 (+) 714 WP_260436835.1 MIP/aquaporin family protein -
  GE021_RS11425 - 585470..585601 (+) 132 WP_284119865.1 hypothetical protein -
  GE021_RS03020 (GE021_003020) - 586216..587211 (+) 996 WP_125074097.1 DUF3114 domain-containing protein -
  GE021_RS03025 (GE021_003025) vicR 587391..588101 (+) 711 WP_125074098.1 response regulator YycF Regulator
  GE021_RS03030 (GE021_003030) vicK 588094..589446 (+) 1353 WP_125074099.1 cell wall metabolism sensor histidine kinase VicK Regulator
  GE021_RS03035 (GE021_003035) vicX 589450..590259 (+) 810 WP_003047202.1 MBL fold metallo-hydrolase Regulator
  GE021_RS03040 (GE021_003040) rnc 590360..591052 (+) 693 WP_003047203.1 ribonuclease III -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27118.01 Da        Isoelectric Point: 4.9038

>NTDB_id=447267 GE021_RS03025 WP_125074098.1 587391..588101(+) (vicR) [Streptococcus canis strain HL_77_1]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTVFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASFGSQELTIGNLQILPDAFVAKKHGQEVE
LTHREFELLHHLANHMGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=447267 GE021_RS03025 WP_125074098.1 587391..588101(+) (vicR) [Streptococcus canis strain HL_77_1]
ATGAAAAAAATACTTATTGTGGATGATGAAAAACCAATTTCTGACATTATTAAGTTTAATTTAACAAAAGAAGGCTATGA
CATTGTCACCGCTTTTGATGGCCGTGAAGCGGTTACTGTTTTTGAAGAAGAAAAGCCAGATCTCATTATTCTTGATTTGA
TGCTGCCCGAACTTGACGGACTTGAAGTGGCCAAAGAAATTCGTAAAACCAGCCATATCCCTATTATCATGCTGTCTGCT
AAAGACAGTGAATTTGACAAGGTTATTGGTCTTGAAATTGGAGCAGATGATTATGTGACGAAACCCTTTTCCAACCGTGA
ATTGTTGGCACGTGTCAAGGCTCACTTACGCCGTACAGAGACCATTGAAACAGCCGTAGCAGAGGAAAATGCTTCTTTTG
GTTCACAAGAATTGACCATTGGTAATTTGCAAATTTTACCCGATGCTTTTGTGGCCAAAAAACATGGTCAAGAGGTGGAA
TTAACCCATCGTGAATTTGAATTATTACATCATCTAGCCAATCACATGGGGCAAGTAATGACACGTGAGCATCTACTTGA
AACGGTTTGGGGCTATGATTACTTTGGCGATGTCCGTACTGTTGATGTGACTGTTCGCCGCCTACGTGAAAAAATTGAAG
ACACACCAAGCCGTCCCGAATATATTTTGACGAGACGTGGTGTTGGGTATTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3P5XNP4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.254

100

0.903
  micA Streptococcus pneumoniae Cp1015

78.632

99.153

0.78
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.828

98.305

0.441
  covR Streptococcus salivarius strain HSISS4

43.777

98.729

0.432
  scnR Streptococcus mutans UA159

37.339

98.729

0.369