Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   GE022_RS06875 Genome accession   NZ_CP053790
Coordinates   1419652..1420362 (-) Length   236 a.a.
NCBI ID   WP_164405232.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_77_2     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1414652..1425362
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE022_RS06860 (GE022_006850) rnc 1416700..1417392 (-) 693 WP_093998381.1 ribonuclease III -
  GE022_RS06865 (GE022_006855) vicX 1417494..1418303 (-) 810 WP_141290703.1 MBL fold metallo-hydrolase Regulator
  GE022_RS06870 (GE022_006860) vicK 1418307..1419659 (-) 1353 WP_125074099.1 cell wall metabolism sensor histidine kinase VicK Regulator
  GE022_RS06875 (GE022_006865) vicR 1419652..1420362 (-) 711 WP_164405232.1 response regulator YycF Regulator
  GE022_RS06880 (GE022_006870) - 1420541..1421536 (-) 996 WP_164405231.1 DUF3114 domain-containing protein -
  GE022_RS10840 - 1422151..1422282 (-) 132 WP_263399211.1 hypothetical protein -
  GE022_RS06890 (GE022_006880) - 1422411..1423121 (-) 711 WP_244951826.1 MIP/aquaporin family protein -
  GE022_RS06895 (GE022_006885) dhaM 1423135..1423509 (-) 375 WP_164405229.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  GE022_RS06900 (GE022_006890) dhaL 1423509..1424084 (-) 576 WP_164405228.1 dihydroxyacetone kinase subunit DhaL -
  GE022_RS06905 (GE022_006895) dhaK 1424095..1425084 (-) 990 WP_159305764.1 dihydroxyacetone kinase subunit DhaK -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27057.95 Da        Isoelectric Point: 5.0023

>NTDB_id=447221 GE022_RS06875 WP_164405232.1 1419652..1420362(-) (vicR) [Streptococcus canis strain HL_77_2]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTVFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFVAKKHGKEVE
LTHREFELLHHLANHMGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=447221 GE022_RS06875 WP_164405232.1 1419652..1420362(-) (vicR) [Streptococcus canis strain HL_77_2]
ATGAAAAAAATACTGATTGTGGATGATGAAAAACCAATTTCTGACATTATTAAGTTTAATTTAACAAAAGAAGGCTATGA
CATTGTCACCGCTTTTGATGGCCGTGAAGCGGTTACTGTTTTTGAAGAAGAAAAGCCAGATCTCATTATTCTTGATTTGA
TGCTGCCCGAACTTGATGGACTTGAAGTGGCCAAAGAAATTCGTAAAACCAGCCATATCCCTATTATCATGCTGTCTGCT
AAAGACAGTGAGTTTGACAAGGTTATTGGTCTTGAAATTGGAGCAGATGATTATGTTACCAAACCCTTTTCAAATCGTGA
ACTATTAGCGCGTGTCAAGGCTCATTTACGTCGAACAGAAACGATCGAAACAGCCGTAGCAGAGGAAAATGCTTCTTCAG
GTTCACAAGAGTTAACCATTGGTAATTTGCAAATTTTACCCGATGCTTTTGTGGCTAAAAAACATGGCAAAGAAGTGGAA
TTAACCCATCGTGAATTTGAATTATTACATCATCTAGCCAATCACATGGGGCAAGTAATGACACGTGAGCATCTACTTGA
AACGGTTTGGGGCTATGATTACTTTGGCGATGTCCGTACTGTTGATGTGACTGTTCGCCGCCTACGTGAAAAAATTGAAG
ACACACCAAGCCGTCCCGAATATATTTTGACGAGACGTGGTGTTGGGTATTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.254

100

0.903
  micA Streptococcus pneumoniae Cp1015

79.06

99.153

0.784
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.828

98.305

0.441
  covR Streptococcus salivarius strain HSISS4

44.828

98.305

0.441
  scnR Streptococcus mutans UA159

38.136

100

0.381