Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   GE022_RS06870 Genome accession   NZ_CP053790
Coordinates   1418307..1419659 (-) Length   450 a.a.
NCBI ID   WP_125074099.1    Uniprot ID   A0A3P5Y8P3
Organism   Streptococcus canis strain HL_77_2     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1413307..1424659
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE022_RS06860 (GE022_006850) rnc 1416700..1417392 (-) 693 WP_093998381.1 ribonuclease III -
  GE022_RS06865 (GE022_006855) vicX 1417494..1418303 (-) 810 WP_141290703.1 MBL fold metallo-hydrolase Regulator
  GE022_RS06870 (GE022_006860) vicK 1418307..1419659 (-) 1353 WP_125074099.1 cell wall metabolism sensor histidine kinase VicK Regulator
  GE022_RS06875 (GE022_006865) vicR 1419652..1420362 (-) 711 WP_164405232.1 response regulator YycF Regulator
  GE022_RS06880 (GE022_006870) - 1420541..1421536 (-) 996 WP_164405231.1 DUF3114 domain-containing protein -
  GE022_RS10840 - 1422151..1422282 (-) 132 WP_263399211.1 hypothetical protein -
  GE022_RS06890 (GE022_006880) - 1422411..1423121 (-) 711 WP_244951826.1 MIP/aquaporin family protein -
  GE022_RS06895 (GE022_006885) dhaM 1423135..1423509 (-) 375 WP_164405229.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  GE022_RS06900 (GE022_006890) dhaL 1423509..1424084 (-) 576 WP_164405228.1 dihydroxyacetone kinase subunit DhaL -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51434.92 Da        Isoelectric Point: 5.3982

>NTDB_id=447220 GE022_RS06870 WP_125074099.1 1418307..1419659(-) (vicK) [Streptococcus canis strain HL_77_2]
MTRDIIGNLSAFELAILLLLVFVAFYFIHLAVRDYRNARIIRMMSHKIRDLINGRYTDMINEKADIELMELADQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLTKEQALEKNITDLLEGDTPYTYRDLVSKTPV
VTVNSRNDMGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLSVEMTNFTAFMTSILNRFDLVKNQHTGTGKVYEIVRDYPITS
VWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEEDID

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=447220 GE022_RS06870 WP_125074099.1 1418307..1419659(-) (vicK) [Streptococcus canis strain HL_77_2]
ATGACTAGAGATATCATCGGGAATTTATCCGCTTTTGAATTAGCGATTCTCTTATTGCTTGTTTTTGTTGCCTTTTACTT
TATTCATTTAGCAGTACGTGATTACCGCAATGCTCGTATTATTCGAATGATGAGCCACAAGATCAGGGATCTGATCAATG
GTCGTTATACCGATATGATTAACGAAAAGGCTGACATTGAATTGATGGAATTGGCAGATCAATTAAACGATCTTTCAGAT
GTTTTTCGCCTAACCCATGAAAATCTTGCCCAGGAAAAAAACCGCCTAGCAAGCATTTTGGCTTATATGTCAGATGGGGT
GCTTGCTACTGACCGGTCTGGGAAAATTATCATGATTAACGAAACAGCTCGCAAGCAATTAAATTTAACTAAGGAACAAG
CCCTTGAAAAGAATATTACAGATTTGTTAGAGGGAGATACGCCTTATACCTACCGTGACTTGGTGTCCAAAACACCAGTG
GTAACTGTTAATAGCCGAAATGATATGGGCGAATTTGTCTCATTGCGTCTGCGCTTTGCCTTGAACAGACGCGAAAGTGG
CTTTATTTCAGGCTTGGTCGTGGTTTTACATGACACCACAGAACAAGAAAAAGAAGAACGTGAACGCCGTCTTTTTGTTT
CCAATGTCAGCCATGAACTTAGGACACCTTTGACCTCGGTTAAATCTTATTTAGAGGCCCTTGACGAAGGTGCCCTCACA
GAAGATATTGCGCCAAGCTTTATCAAGGTTTCTCTTGATGAGACCAATCGAATGATGCGAATGATTTCCGATCTTTTGAA
CCTGTCTCGCATTGATAACCAAGTGACCCAGTTGTCAGTCGAAATGACCAATTTCACAGCCTTTATGACCTCTATTCTGA
ACCGATTTGACCTAGTTAAAAACCAACATACGGGTACAGGCAAGGTCTATGAAATTGTGAGGGATTACCCCATTACTTCT
GTTTGGTTAGAAATTGACAATGACAAGATGACACAGGTTATTGAAAATATTCTTAATAATGCCATTAAATATTCTCCTGA
TGGTGGGAAAATCACTGTTCGCATGAAAACAACAGACACGCAGTTGATTATTTCCATTTCTGATCAGGGTCTCGGCATTC
CTAAAAAGGATTTGCCCCTTATTTTTGACCGATTTTACCGTGTGGACAAGGCAAGAAGCCGTGCTCAGGGCGGTACTGGA
CTAGGCCTTGCCATTGCTAAAGAAATTATCAAGCAGCATCACGGCTTCATCTGGGCTAAAAGTGATTATGGCAAGGGATC
AACCTTTACCATTGTCTTGCCTTATGAAAAAGATGCTGCCATTTATGAAGAATGGGAGGAAGATATAGATTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(95-164)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3P5Y8P3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.913

92

0.68
  micB Streptococcus pneumoniae Cp1015

67.059

94.444

0.633