Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   GE023_RS07185 Genome accession   NZ_CP053789
Coordinates   1457094..1457804 (-) Length   236 a.a.
NCBI ID   WP_003047198.1    Uniprot ID   A0AAV3FQU3
Organism   Streptococcus canis strain HL_98_2     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1452094..1462804
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE023_RS07170 (GE023_007165) rnc 1454142..1454834 (-) 693 WP_003047203.1 ribonuclease III -
  GE023_RS07175 (GE023_007170) vicX 1454936..1455745 (-) 810 WP_159304642.1 MBL fold metallo-hydrolase Regulator
  GE023_RS07180 (GE023_007175) vicK 1455749..1457101 (-) 1353 WP_093998382.1 cell wall metabolism sensor histidine kinase VicK Regulator
  GE023_RS07185 (GE023_007180) vicR 1457094..1457804 (-) 711 WP_003047198.1 response regulator YycF Regulator
  GE023_RS07190 (GE023_007185) - 1457984..1458979 (-) 996 WP_159305761.1 DUF3114 domain-containing protein -
  GE023_RS07195 (GE023_007190) - 1459188..1459457 (-) 270 WP_159305762.1 hypothetical protein -
  GE023_RS07200 (GE023_007195) - 1459853..1460563 (-) 711 WP_159305763.1 MIP/aquaporin family protein -
  GE023_RS07205 (GE023_007200) dhaM 1460577..1460951 (-) 375 WP_003047188.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  GE023_RS07210 (GE023_007205) dhaL 1460951..1461526 (-) 576 WP_003047186.1 dihydroxyacetone kinase subunit DhaL -
  GE023_RS07215 (GE023_007210) dhaK 1461537..1462526 (-) 990 WP_159305764.1 dihydroxyacetone kinase subunit DhaK -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27057.91 Da        Isoelectric Point: 4.9038

>NTDB_id=447167 GE023_RS07185 WP_003047198.1 1457094..1457804(-) (vicR) [Streptococcus canis strain HL_98_2]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTVFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFVAKKHGQEVE
LTHREFELLHHLANHMGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=447167 GE023_RS07185 WP_003047198.1 1457094..1457804(-) (vicR) [Streptococcus canis strain HL_98_2]
ATGAAAAAAATACTTATTGTGGATGATGAAAAACCAATTTCTGACATTATTAAGTTTAATTTAACAAAAGAAGGCTATGA
CATTGTCACCGCTTTTGATGGCCGTGAAGCGGTTACTGTTTTTGAAGAAGAAAAGCCAGATCTCATTATTCTTGATTTGA
TGCTGCCCGAACTTGATGGACTTGAAGTGGCCAAAGAAATTCGTAAAACCAGCCATATCCCTATTATCATGCTGTCTGCT
AAAGACAGTGAGTTTGACAAGGTTATTGGTCTTGAAATTGGAGCAGATGATTATGTGACGAAACCCTTTTCCAACCGTGA
ATTGTTGGCACGTGTCAAGGCTCACTTACGCCGTACAGAGACCATTGAAACAGCCGTAGCAGAGGAAAATGCTTCTTCTG
GTTCGCAAGAATTGACCATTGGTAATTTGCAAATTTTACCCGATGCTTTTGTGGCCAAAAAACATGGTCAAGAGGTGGAA
TTAACCCATCGTGAATTTGAATTATTACATCATCTAGCCAATCACATGGGGCAAGTAATGACACGTGAGCATCTACTTGA
AACGGTTTGGGGCTATGATTACTTTGGCGATGTCCGTACTGTTGATGTGACTGTTCGCCGCCTACGTGAAAAAATTGAAG
ACACACCAAGCCGTCCCGAATATATTTTGACGAGACGTGGTGTTGGGTATTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.254

100

0.903
  micA Streptococcus pneumoniae Cp1015

79.06

99.153

0.784
  covR Streptococcus salivarius strain HSISS4

44.828

98.305

0.441
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

38.136

100

0.381