Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   GE023_RS07180 Genome accession   NZ_CP053789
Coordinates   1455749..1457101 (-) Length   450 a.a.
NCBI ID   WP_093998382.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_98_2     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1450749..1462101
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE023_RS07170 (GE023_007165) rnc 1454142..1454834 (-) 693 WP_003047203.1 ribonuclease III -
  GE023_RS07175 (GE023_007170) vicX 1454936..1455745 (-) 810 WP_159304642.1 MBL fold metallo-hydrolase Regulator
  GE023_RS07180 (GE023_007175) vicK 1455749..1457101 (-) 1353 WP_093998382.1 cell wall metabolism sensor histidine kinase VicK Regulator
  GE023_RS07185 (GE023_007180) vicR 1457094..1457804 (-) 711 WP_003047198.1 response regulator YycF Regulator
  GE023_RS07190 (GE023_007185) - 1457984..1458979 (-) 996 WP_159305761.1 DUF3114 domain-containing protein -
  GE023_RS07195 (GE023_007190) - 1459188..1459457 (-) 270 WP_159305762.1 hypothetical protein -
  GE023_RS07200 (GE023_007195) - 1459853..1460563 (-) 711 WP_159305763.1 MIP/aquaporin family protein -
  GE023_RS07205 (GE023_007200) dhaM 1460577..1460951 (-) 375 WP_003047188.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  GE023_RS07210 (GE023_007205) dhaL 1460951..1461526 (-) 576 WP_003047186.1 dihydroxyacetone kinase subunit DhaL -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51420.90 Da        Isoelectric Point: 5.3982

>NTDB_id=447166 GE023_RS07180 WP_093998382.1 1455749..1457101(-) (vicK) [Streptococcus canis strain HL_98_2]
MTRDIIGNLSAFELAILLLLVFVAFYFIHLAVRDYRNARIVRMMSHKIRDLINGRYTDMINEKADIELMELADQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLTKEQALEKNITDLLEGDTPYTYRDLVSKTPV
VTVNSRNDMGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLSVEMTNFTAFMTSILNRFDLVKNQHTGTGKVYEIVRDYPITS
VWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEEDID

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=447166 GE023_RS07180 WP_093998382.1 1455749..1457101(-) (vicK) [Streptococcus canis strain HL_98_2]
ATGACTAGAGATATCATCGGGAATTTATCCGCTTTTGAATTAGCGATTCTCTTATTGCTTGTTTTTGTTGCCTTTTACTT
TATTCATTTAGCAGTGCGGGATTACCGCAATGCTCGTATTGTTCGAATGATGAGCCACAAGATCAGGGATCTGATCAATG
GTCGTTATACCGATATGATTAACGAAAAGGCTGACATTGAATTGATGGAATTGGCAGATCAATTAAACGATCTTTCAGAT
GTTTTTCGCCTAACCCATGAAAATCTTGCCCAGGAAAAAAACCGCCTAGCAAGCATTTTGGCTTATATGTCAGATGGGGT
GCTTGCTACTGACCGGTCTGGGAAAATTATCATGATTAACGAAACAGCTCGCAAGCAATTAAATTTAACTAAGGAACAAG
CCCTTGAAAAGAATATTACAGATTTGTTAGAGGGAGACACGCCTTATACCTACCGTGACTTGGTGTCCAAAACACCAGTG
GTAACTGTTAATAGCCGAAATGATATGGGCGAATTTGTCTCATTGCGTCTGCGCTTTGCCTTGAACAGACGCGAAAGTGG
CTTTATTTCAGGCTTGGTCGTGGTTTTACATGACACCACAGAACAAGAAAAAGAAGAACGTGAACGCCGTCTTTTTGTTT
CCAATGTCAGCCATGAGCTTAGGACACCTTTGACCTCGGTTAAATCTTATTTAGAGGCCCTTGACGAAGGTGCCCTCACA
GAAGATATTGCGCCAAGCTTTATCAAGGTTTCTCTTGATGAGACCAATCGAATGATGCGAATGATTTCCGATCTTTTGAA
CCTGTCTCGCATTGATAACCAAGTGACCCAGTTGTCAGTCGAAATGACCAATTTCACAGCCTTTATGACCTCTATTCTGA
ACCGATTTGACCTAGTTAAAAACCAACATACGGGTACAGGCAAGGTCTATGAAATTGTGAGGGATTACCCCATTACTTCT
GTTTGGTTAGAAATTGACAATGACAAGATGACACAGGTTATTGAAAATATTCTTAATAATGCCATTAAATATTCTCCTGA
TGGTGGGAAAATCACTGTTCGCATGAAAACAACAGACACGCAGTTGATTATTTCCATTTCTGATCAGGGTCTCGGCATTC
CTAAAAAGGATTTGCCCCTTATTTTTGACCGATTTTACCGTGTGGACAAGGCAAGAAGCCGTGCTCAGGGCGGTACTGGA
CTAGGCCTTGCCATTGCTAAAGAAATTATCAAGCAGCATCACGGCTTCATCTGGGCTAAAAGTGATTATGGCAAGGGATC
AACCTTTACCATTGTCTTGCCTTATGAAAAAGATGCTGCCATTTATGAAGAATGGGAGGAAGATATAGATTAA

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-164)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.155

92

0.682
  micB Streptococcus pneumoniae Cp1015

67.059

94.444

0.633