Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   C270_RS06280 Genome accession   NC_018673
Coordinates   1278592..1279194 (-) Length   200 a.a.
NCBI ID   WP_014974736.1    Uniprot ID   K0DDP6
Organism   Leuconostoc carnosum JB16     
Function   degradation of ComX; require for competence development (at the early growth phase); repress competence development (at the mid-logarithmic growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1273592..1284194
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C270_RS06260 (C270_06065) - 1274245..1274781 (-) 537 WP_014974732.1 YqeG family HAD IIIA-type phosphatase -
  C270_RS06265 (C270_06070) - 1274931..1275602 (-) 672 WP_014974733.1 hypothetical protein -
  C270_RS06270 (C270_06075) - 1275968..1277206 (-) 1239 WP_014974734.1 PTS sugar transporter subunit IIC -
  C270_RS06275 (C270_06080) - 1277322..1278317 (-) 996 WP_014974735.1 D-2-hydroxyacid dehydrogenase -
  C270_RS06280 (C270_06085) clpP 1278592..1279194 (-) 603 WP_014974736.1 ATP-dependent Clp protease proteolytic subunit Regulator
  C270_RS06285 (C270_06090) whiA 1279374..1280318 (-) 945 WP_014974737.1 DNA-binding protein WhiA -
  C270_RS06290 (C270_06095) - 1280318..1281292 (-) 975 WP_014974738.1 gluconeogenesis factor YvcK family protein -
  C270_RS09015 (C270_06100) - 1281532..1281654 (+) 123 WP_014974739.1 putative metal homeostasis protein -

Sequence

Protein


Download         Length: 200 a.a.        Molecular weight: 21586.75 Da        Isoelectric Point: 4.7491

>NTDB_id=44677 C270_RS06280 WP_014974736.1 1278592..1279194(-) (clpP) [Leuconostoc carnosum JB16]
MWPGVIEQTANGRESYDLPSRLLKDRIVLVQGEIEDSMATSIAAQLLFLEAQDPTKEISMYINSPGGSVTAGLSITDTMN
FIKAPVTTIVMGLAASMGTIIASSGEKGHRFMLPNAEYLIHQPMGGAGGGTQQTDMAIIAKQLTKTREKLNKILANASGK
DLETIAHDTERDYWMSAEETLEYGLIDGILTKAGEKPVIK

Nucleotide


Download         Length: 603 bp        

>NTDB_id=44677 C270_RS06280 WP_014974736.1 1278592..1279194(-) (clpP) [Leuconostoc carnosum JB16]
ATGTGGCCAGGAGTTATTGAACAAACTGCTAATGGACGTGAAAGCTATGATTTACCTTCACGTTTGCTAAAGGATCGTAT
TGTTTTGGTTCAAGGCGAAATTGAAGATAGTATGGCGACATCAATTGCTGCGCAATTACTATTTTTGGAAGCGCAAGATC
CAACAAAAGAAATTTCAATGTATATTAATTCACCAGGGGGCTCAGTTACAGCTGGACTATCAATTACTGATACAATGAAT
TTCATTAAAGCACCGGTAACAACAATTGTTATGGGATTAGCTGCTTCAATGGGAACTATCATTGCTAGTTCAGGTGAGAA
GGGGCATCGGTTTATGTTGCCCAATGCCGAATACCTGATTCACCAACCAATGGGTGGTGCTGGTGGCGGTACGCAACAGA
CTGATATGGCAATTATTGCTAAGCAGTTGACTAAGACACGTGAAAAACTAAATAAGATTCTAGCAAATGCGTCAGGGAAA
GACTTAGAAACAATCGCGCATGACACAGAGCGTGATTATTGGATGAGTGCTGAAGAAACGTTGGAATATGGTTTGATTGA
TGGCATTTTAACAAAAGCCGGCGAGAAACCAGTTATTAAGTAA

Domains

Predicted by InterProScan.

Clp protease (CLP_protease)

(12-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB K0DDP6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Streptococcus mutans UA159

71.579

95

0.68
  clpP Streptococcus thermophilus LMG 18311

69.792

96

0.67
  clpP Streptococcus thermophilus LMD-9

69.792

96

0.67
  clpP Streptococcus pyogenes MGAS315

70

95

0.665
  clpP Streptococcus pyogenes JRS4

70

95

0.665
  clpP Streptococcus pneumoniae Rx1

69.474

95

0.66
  clpP Streptococcus pneumoniae D39

69.474

95

0.66
  clpP Streptococcus pneumoniae R6

69.474

95

0.66
  clpP Streptococcus pneumoniae TIGR4

69.474

95

0.66
  clpP Lactococcus lactis subsp. cremoris KW2

69.681

94

0.655
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

69.149

94

0.65
  clpP Bacillus subtilis subsp. subtilis str. 168

57.653

98

0.565
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.545

95.5

0.54

Multiple sequence alignment