Detailed information NTG0439478

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: INP70_RS11855
• Genome accession: NZ_CP063420
• Coordinates: 2620963..2623785 (+)
• Length: 940 a.a.
• NCBI ID: WP_000357696.1
• Uniprot ID: Q9KUW5
• Organism: Vibrio cholerae strain VC_hf7
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2615963..2628785

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
INP70_RS11835	csrD	2616157..2618169 (-)	2013	WP_002022932.1	RNase E specificity factor CsrD	-
INP70_RS11840	ssb	2618293..2618826 (-)	534	WP_000168287.1	single-stranded DNA-binding protein	Machinery gene
INP70_RS11845	qstR	2619118..2619762 (+)	645	WP_001188315.1	LuxR C-terminal-related transcriptional regulator	Regulator
INP70_RS11850	galU	2619935..2620807 (+)	873	WP_001920788.1	UTP--glucose-1-phosphate uridylyltransferase GalU	-
INP70_RS11855	uvrA	2620963..2623785 (+)	2823	WP_000357696.1	excinuclease ABC subunit UvrA	Machinery gene
INP70_RS11860	-	2623850..2625634 (+)	1785	WP_000212626.1	oligosaccharyltransferase	-
INP70_RS11865	-	2625713..2626831 (-)	1119	WP_000155555.1	alanine--glyoxylate aminotransferase family protein	-
INP70_RS11870	lysC	2627295..2628650 (+)	1356	WP_000102982.1	lysine-sensitive aspartokinase 3	-

Sequence

Protein

• Length: 940 a.a.
• Molecular weight: 104327.86 Da
• Isoelectric Point: 6.4814

>NTDB_id=439478 INP70_RS11855 WP_000357696.1 2620963..2623785(+) (uvrA) [Vibrio cholerae strain VC_hf7]
MDKIEVRGARTHNLKNINLTIPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS
PAISIEQKSTSHNPRSTVGTITEVYDYLRLLYARVGEPRCPEHQVPLKAQTISQMVDKVLELPEGSKMMLLATIVKERKG
EHVKTLENLAAQGFIRARIDGETCDLTDPPKLELHKKHTIEVIVDRFKVRSDLQQRLAESFETALELSGGIVVVAPMEGD
GEEQIFSANFACPHCGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQDANLSLAQGAIRGWDQKNFYYFQML
TALAEHYDFDVHTPFNKLSKKIQEIILHGSGRTEIEFKYINDRGDIRLKKHPFEGILHNLERRYRDTESNSVREELAKYI
SNKPCSSCDGTRLKIEARNVFINDTALPTIVELSIADALTFFQELKLEGQRAQIAEKVMKEINDRLQFLVNVGLNYLNLS
RSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLQTLTHLRNLGNTVLVVEHDEDAIRMADHVIDIG
PGAGVHGGMVVAEGNVEEIIANPNSLTGQYLSGVKKIAVPEQRTPKDAKKTVELKGAVGNNLKNVDLSIPVGLFTCVTGV
SGSGKSTLINDTFFKIAHTALNGATTATPAPYRSIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPIRELFAGTQES
RSRGYQPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDVYVPCDVCKGKRYNRETLEVRYKGKTIDEVLDMTVEDAREFFD
PVPVIARKLQTLMDVGLSYIRLGQSATTLSGGEAQRVKLARELSKRDTGKTLYILDEPTTGLHFHDIQQLLSVLHRLRDH
GNTVVVIEHNLDVIKTADWIIDLGPEGGQGGGLIIAEGTPEDVAQIEASHTARFLKPLLN

Nucleotide

• Length: 2823 bp

>NTDB_id=439478 INP70_RS11855 WP_000357696.1 2620963..2623785(+) (uvrA) [Vibrio cholerae strain VC_hf7]
ATGGACAAAATCGAAGTACGCGGCGCTCGTACCCATAACCTCAAAAATATCAATCTGACCATTCCTCGTGACAAATTGAT
TGTCATCACCGGCCTCTCTGGTTCAGGTAAATCCTCACTGGCTTTTGATACGCTGTACGCAGAAGGTCAACGGCGTTATG
TCGAATCGCTCTCGGCTTATGCGCGCCAATTCCTTTCTCTGATGGAAAAGCCGGATGTAGACCACATTGAGGGGCTTTCA
CCCGCGATTTCGATTGAGCAGAAGTCCACTTCCCATAACCCACGCTCTACTGTGGGTACGATTACGGAAGTGTATGACTA
TTTACGTCTACTCTACGCTCGGGTTGGTGAGCCACGCTGCCCCGAACACCAAGTGCCACTGAAAGCGCAAACCATCAGTC
AGATGGTAGACAAAGTACTGGAATTGCCAGAAGGCAGCAAAATGATGCTGCTGGCAACCATAGTCAAAGAGCGCAAAGGC
GAACACGTTAAAACATTGGAAAACCTTGCTGCGCAGGGCTTTATTCGTGCGCGTATCGATGGTGAAACCTGCGATCTGAC
CGATCCACCGAAACTCGAACTGCACAAAAAGCACACCATTGAAGTAATTGTCGACCGTTTCAAAGTGCGCAGTGATCTGC
AGCAACGCTTAGCCGAATCCTTTGAAACCGCCTTAGAACTTTCCGGTGGTATCGTCGTTGTCGCACCGATGGAAGGCGAT
GGCGAAGAGCAGATTTTCTCGGCTAACTTTGCTTGTCCACATTGCGGTTACAGCATGCGCGAACTGGAACCACGCCTGTT
CTCCTTCAACAACCCAGCCGGTGCTTGTCCAACCTGTGATGGTTTAGGAGTACAGCAGTATTTCGATCCAGATCGAGTGA
TTCAAGATGCCAATTTAAGTTTGGCACAAGGCGCGATCCGCGGTTGGGATCAAAAGAACTTTTATTATTTCCAGATGCTG
ACTGCACTGGCCGAGCACTACGATTTTGATGTACACACTCCCTTCAATAAGCTGAGCAAAAAGATTCAGGAAATCATTCT
GCACGGCTCTGGTCGCACCGAAATTGAATTTAAGTACATCAATGATCGGGGTGATATTCGCCTCAAAAAGCACCCTTTTG
AAGGGATTTTGCATAATTTGGAGCGCCGCTATCGCGATACCGAATCCAACTCGGTGCGTGAGGAGCTGGCAAAATACATC
TCCAACAAGCCTTGCAGCAGTTGTGATGGTACGCGCTTAAAAATCGAAGCACGCAATGTGTTTATTAATGATACTGCGTT
GCCAACGATTGTAGAACTGAGCATTGCTGATGCGCTAACGTTCTTCCAAGAGCTCAAACTGGAAGGCCAACGTGCACAAA
TCGCTGAAAAAGTGATGAAAGAGATTAATGACCGGCTGCAATTTTTGGTCAATGTCGGGCTCAATTACTTAAATCTCTCG
CGCAGCGCCGAGACGCTTTCCGGTGGCGAAGCTCAGCGTATTCGCCTAGCCAGTCAGATTGGTGCCGGTTTAGTCGGTGT
AATGTATGTCCTTGATGAACCCTCGATTGGCCTCCACCAACGCGACAACGAACGCTTGCTGCAAACCCTCACCCACTTAC
GCAATCTAGGGAATACCGTGTTAGTGGTTGAGCATGATGAAGATGCGATTCGCATGGCAGATCATGTGATTGATATTGGC
CCAGGTGCTGGCGTACACGGCGGCATGGTGGTTGCCGAAGGCAATGTGGAGGAAATCATCGCCAATCCAAACTCACTCAC
AGGTCAATATCTCAGTGGCGTGAAAAAAATCGCGGTACCAGAGCAGCGCACACCAAAAGATGCGAAGAAAACGGTAGAGC
TTAAAGGCGCAGTCGGTAATAACTTAAAAAATGTTGACCTGTCTATTCCTGTTGGCCTGTTTACTTGTGTGACGGGCGTT
TCAGGTTCGGGAAAATCCACTCTGATCAACGATACCTTCTTTAAGATTGCCCATACCGCACTCAATGGCGCGACGACGGC
GACACCTGCACCTTATCGCTCCATTCAAGGTCTAGAACACTTTGATAAAGTGATCGATATCGATCAGAGCCCAATTGGTC
GCACTCCTCGCTCCAACCCTGCCACTTACACCGGAATCTTCACTCCAATCCGTGAATTGTTTGCAGGAACACAAGAGTCT
CGCTCGCGTGGTTATCAGCCGGGACGCTTTAGTTTTAACGTCCGCGGAGGGCGCTGTGAAGCGTGCCAAGGCGATGGCGT
GATCAAAGTTGAAATGCACTTCTTACCCGATGTGTATGTGCCTTGTGATGTGTGTAAAGGTAAACGCTATAACCGAGAAA
CACTGGAAGTGCGCTACAAAGGCAAGACGATTGATGAAGTTTTGGACATGACCGTTGAAGACGCACGCGAGTTTTTTGAC
CCCGTACCTGTGATAGCACGTAAGCTGCAAACCTTGATGGATGTTGGGTTGTCCTACATTCGTCTTGGGCAATCAGCCAC
CACCTTATCAGGAGGTGAAGCGCAGCGGGTAAAATTAGCACGTGAACTCTCCAAACGAGATACGGGCAAAACCCTGTATA
TTTTGGATGAACCAACCACGGGCCTTCACTTCCACGATATTCAGCAACTATTGAGCGTTCTGCACCGCTTGCGTGACCAT
GGCAATACCGTGGTGGTGATTGAGCATAACTTGGATGTGATCAAAACGGCTGATTGGATCATCGATTTAGGCCCCGAAGG
CGGTCAAGGCGGCGGACTGATTATTGCAGAAGGAACACCAGAAGATGTGGCGCAGATCGAAGCTTCACATACCGCACGTT
TCCTCAAGCCTTTGTTGAATTAG

Domains

Predicted by InterProScan.

• UvrA interaction domain (UvrA_inter) (130-236)

• UvrA DNA-binding domain (UvrA_DNA-bind) (289-398)

• ABC transporter (ABC_tran) (622-859)

3D structure

• AlphaFold DB: Q9KUW5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	57.9	100	0.581
uvrA	Streptococcus pneumoniae TIGR4	57.9	100	0.581
uvrA	Streptococcus pneumoniae D39	57.9	100	0.581