Detailed information NTG0043682

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: LP12_RS12955
• Genome accession: NC_016811
• Coordinates: 2890605..2891690 (+)
• Length: 361 a.a.
• NCBI ID: WP_010948297.1
• Uniprot ID: A0AAN5SZF3
• Organism: Legionella pneumophila subsp. pneumophila ATCC 43290
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 2885605..2896690

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LP12_RS12930 (lp12_2585)	-	2885998..2886747 (-)	750	WP_010948292.1	type II CAAX prenyl endopeptidase Rce1 family protein	-
LP12_RS12935 (lp12_2586)	rsmB	2886744..2888027 (-)	1284	WP_010948293.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
LP12_RS12940 (lp12_2587)	fmt	2888024..2888968 (-)	945	WP_010948294.1	methionyl-tRNA formyltransferase	-
LP12_RS12945 (lp12_2588)	def	2888965..2889477 (-)	513	WP_010948295.1	peptide deformylase	-
LP12_RS12950 (lp12_2589)	-	2889571..2890608 (+)	1038	WP_010948296.1	LysM peptidoglycan-binding domain-containing protein	-
LP12_RS12955 (lp12_2590)	dprA	2890605..2891690 (+)	1086	WP_010948297.1	DNA-processing protein DprA	Machinery gene
LP12_RS12960 (lp12_2591)	-	2891680..2892117 (+)	438	WP_015444006.1	DUF494 family protein	-
LP12_RS12965 (lp12_2592)	topA	2892196..2894475 (+)	2280	WP_010948299.1	type I DNA topoisomerase	-
LP12_RS12970 (lp12_2593)	-	2894577..2896550 (-)	1974	WP_010948300.1	acyltransferase family protein	-

Sequence

Protein

• Length: 361 a.a.
• Molecular weight: 39545.75 Da
• Isoelectric Point: 7.5076

>NTDB_id=43682 LP12_RS12955 WP_010948297.1 2890605..2891690(+) (dprA) [Legionella pneumophila subsp. pneumophila ATCC 43290]
MNNLQPLLALNRMKKIGPRTVLKLQKRWPDLNLMFQLSNVDLEEAGLPSWLAQTIKNFDPGFIKTDLNWLSSSENHHILT
WDSPYYPALLKEIADPPFILYAKGELSAMTQPNLAIVGSRNASVTGNENARAFSREISRHGVSIVSGLALGIDAHAHLGC
LEGGGKTIAVLGTGIDCIYPRRHLKLAEQITENGLLLSEFPLKSPPIAGHFPLRNRIISGLSLCILVIEAAIKSGSLITA
RMALEQNRDVLAIPGSIHNPLARGCHYLLQQGAKLVTSVADVLDELKIEHHQFTSNKPIFSLASGKENLVKFIGFETTTI
DQIIDRSGYGMEQVTSGLAELELKGAVMAVPGGYIRCEYER

Nucleotide

• Length: 1086 bp

>NTDB_id=43682 LP12_RS12955 WP_010948297.1 2890605..2891690(+) (dprA) [Legionella pneumophila subsp. pneumophila ATCC 43290]
ATGAATAATCTGCAACCCCTCCTCGCCTTAAACAGGATGAAAAAAATTGGCCCCCGAACCGTATTAAAACTGCAAAAAAG
ATGGCCTGATTTAAACCTTATGTTCCAACTGTCAAATGTTGATCTGGAAGAAGCGGGCTTGCCATCCTGGTTGGCACAAA
CCATAAAAAATTTTGATCCGGGCTTTATAAAAACTGATTTGAACTGGTTAAGTTCATCAGAAAATCATCATATTTTAACT
TGGGACTCCCCCTATTATCCCGCATTGCTCAAAGAAATAGCCGATCCTCCCTTCATTTTATACGCTAAAGGTGAGCTGTC
CGCCATGACACAACCCAACCTGGCTATTGTTGGAAGTCGCAATGCTTCTGTAACAGGAAACGAGAATGCCCGCGCATTCT
CCAGGGAAATTTCCAGGCATGGGGTAAGCATAGTGAGTGGTTTAGCTTTGGGAATTGATGCTCATGCTCATTTAGGCTGT
CTGGAAGGAGGCGGCAAAACGATAGCGGTCTTAGGTACCGGAATTGATTGTATCTATCCGCGCCGGCATTTAAAATTAGC
TGAGCAAATTACAGAGAATGGTTTATTATTAAGCGAATTTCCTTTAAAAAGTCCACCAATTGCTGGACATTTTCCACTCA
GAAATCGTATAATAAGCGGTCTATCATTATGCATTTTGGTTATCGAGGCAGCAATTAAAAGCGGTTCTTTAATTACAGCA
AGAATGGCTCTGGAACAAAACAGAGATGTATTGGCTATTCCCGGATCAATTCATAACCCGTTAGCCAGGGGCTGCCACTA
CTTATTGCAACAGGGTGCGAAATTAGTAACTTCAGTGGCTGATGTTCTTGATGAGCTAAAAATCGAGCACCATCAGTTCA
CTTCTAATAAACCAATTTTTTCCCTTGCCAGCGGTAAGGAAAACCTAGTAAAGTTCATTGGTTTTGAAACTACGACTATC
GATCAAATCATTGATCGTAGCGGATATGGCATGGAACAAGTCACGAGTGGACTGGCTGAACTAGAATTGAAAGGGGCTGT
GATGGCAGTGCCCGGTGGCTATATAAGGTGTGAATATGAAAGATAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (74-277)

• DprA winged helix domain (DprA_WH) (300-353)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Legionella pneumophila strain ERS1305867	98.338	100	0.983
dprA	Vibrio cholerae strain A1552	42.781	100	0.443
dprA	Vibrio campbellii strain DS40M4	44.444	99.723	0.443
dprA	Glaesserella parasuis strain SC1401	38.933	100	0.404
dprA	Haemophilus influenzae Rd KW20	46.048	80.609	0.371