Detailed information NTG0043681

Bioinformatically predicted

Overview

• Name: lqsT
• Type: Regulator
• Locus tag: LP12_RS12485
• Genome accession: NC_016811
• Coordinates: 2785707..2786969 (+)
• Length: 420 a.a.
• NCBI ID: WP_010948208.1
• Uniprot ID: Q5ZSL1
• Organism: Legionella pneumophila subsp. pneumophila ATCC 43290
• Function: repress natural transformation (predicted from homology) Competence regulation

Genomic Context

Location: 2780707..2791969

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LP12_RS12470 (lp12_2496)	-	2780965..2781285 (-)	321	WP_010948205.1	hypothetical protein	-
LP12_RS12475 (lp12_2497)	ceg32	2781593..2784421 (+)	2829	WP_010948206.1	Dot/Icm T4SS effector Ceg32/SidI	-
LP12_RS12480 (lp12_2498)	mesI	2784423..2785310 (+)	888	WP_010948207.1	Dot/Icm T4SS metaeffector MesI	-
LP12_RS12485 (lp12_2499)	lqsT	2785707..2786969 (+)	1263	WP_010948208.1	sensor histidine kinase	Regulator
LP12_RS12490 (lp12_2500)	-	2787017..2787712 (-)	696	WP_010948209.1	iron-containing redox enzyme family protein	-
LP12_RS12495 (lp12_2501)	sdjA	2788111..2790534 (-)	2424	WP_010948210.1	Dot/Icm T4SS effector SdjA	-
LP12_RS12500 (lp12_2502)	dupB	2790605..2791798 (-)	1194	WP_010948211.1	Dot/Icm T4SS effector deubiquitinase DupB/LaiF	-

Sequence

Protein

• Length: 420 a.a.
• Molecular weight: 48657.07 Da
• Isoelectric Point: 7.9744

>NTDB_id=43681 LP12_RS12485 WP_010948208.1 2785707..2786969(+) (lqsT) [Legionella pneumophila subsp. pneumophila ATCC 43290]
MQRLKNIFTAIYQYLLKETEDASHQITLFGIVMMINYPLFGVFWKLEHFQLTEEFILRITAALLCACLAFNQFWPRQLLK
FLPVFWYIVLLFCLPYFFAYLTLINNGSTLWLMNCVSAIFFLLLVSSVLGALILLISGVGLAFFHFYILSNNQFVYIPGT
ISLFSLIVTFIAAIIIGALFARDREITYAGRLSGMRMLAGSIAHDLRTPLASIYLQAELQELIVERLNNPEVQKDLKENL
SKITRGIEMSNQLIRMQLNNIQRDKLDTSTFSIYSIKKLLKASLEEYPFKENQKSLIHLNDKNDFSIWIDEVGFKNMMWN
LLKNSLEYIEETHKGEISIWLEQGWEKENFNYLHIKDTAKGLNHKEYEKIFDFFYSGRKEGTGLGLAYCKLLMQAAGGDI
SCKGKKNEFAHFTLKFPKID

Nucleotide

• Length: 1263 bp

>NTDB_id=43681 LP12_RS12485 WP_010948208.1 2785707..2786969(+) (lqsT) [Legionella pneumophila subsp. pneumophila ATCC 43290]
ATGCAAAGGTTAAAAAATATATTTACTGCAATTTACCAATATTTATTAAAAGAAACTGAAGATGCAAGCCACCAAATCAC
TTTATTTGGCATCGTCATGATGATTAATTACCCTCTTTTCGGAGTTTTCTGGAAACTGGAGCATTTTCAACTGACAGAAG
AATTTATTTTACGCATCACTGCAGCCCTCCTCTGTGCCTGTTTGGCATTTAATCAATTTTGGCCAAGACAATTATTAAAA
TTTCTACCTGTTTTTTGGTATATAGTTCTTCTCTTTTGTTTGCCTTACTTTTTTGCTTATTTGACTCTCATAAACAATGG
CTCGACTCTTTGGCTAATGAATTGCGTATCCGCTATCTTTTTTCTTTTATTAGTTTCCAGTGTATTGGGGGCTCTTATAT
TACTTATATCAGGTGTTGGACTTGCTTTTTTTCATTTTTATATTTTATCAAATAATCAGTTTGTCTATATCCCAGGAACC
ATATCACTTTTTAGTTTAATTGTTACGTTTATTGCAGCAATAATCATTGGTGCCTTGTTTGCACGAGATAGAGAAATTAC
CTATGCCGGACGTTTATCGGGTATGCGCATGCTGGCTGGAAGTATCGCTCATGATTTAAGAACGCCGCTTGCCAGTATTT
ATTTACAAGCCGAATTACAGGAATTGATTGTCGAAAGATTAAATAATCCAGAAGTTCAAAAGGACCTGAAGGAAAATTTA
AGCAAAATTACTCGCGGCATAGAAATGAGTAATCAATTAATTCGTATGCAATTAAATAATATTCAACGAGACAAATTAGA
TACCAGTACATTTTCGATTTATTCCATCAAAAAATTGCTCAAGGCGTCTTTAGAAGAATACCCTTTCAAAGAAAATCAAA
AATCATTGATTCATTTAAATGATAAAAATGATTTTTCCATATGGATTGATGAAGTGGGTTTTAAAAATATGATGTGGAAT
TTGCTAAAAAATAGTCTGGAATATATTGAGGAAACCCATAAAGGCGAAATCTCTATCTGGCTAGAACAAGGATGGGAGAA
AGAGAATTTTAATTACCTCCATATAAAAGATACAGCTAAAGGTTTAAATCATAAAGAATATGAAAAAATATTTGATTTCT
TCTATTCTGGCAGAAAAGAAGGAACTGGTTTAGGCTTGGCCTATTGTAAACTTCTGATGCAAGCAGCAGGCGGTGATATT
TCCTGTAAAGGGAAAAAAAATGAATTCGCTCATTTCACTTTAAAATTCCCCAAAATTGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (310-417)

• His Kinase A (phospho-acceptor) domain (HisKA) (198-255)

3D structure

• AlphaFold DB: Q5ZSL1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
lqsT	Legionella pneumophila subsp. pneumophila str. Philadelphia 1	100	100	1