Detailed information NTG0436066

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: HCM98_RS12900
• Genome accession: NZ_CP051013
• Coordinates: 2485384..2485965 (+)
• Length: 193 a.a.
• NCBI ID: WP_000991609.1
• Uniprot ID: A0A853X8N5
• Organism: Bacillus tropicus strain LM1212-DB
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2480384..2490965

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HCM98_RS12875 (HCM98_12895)	-	2481498..2482865 (+)	1368	WP_029438608.1	lytic polysaccharide monooxygenase	-
HCM98_RS12880 (HCM98_12900)	-	2482996..2483430 (-)	435	WP_029438607.1	GNAT family N-acetyltransferase	-
HCM98_RS12885 (HCM98_12905)	rpiA	2483545..2484207 (-)	663	WP_029438606.1	ribose 5-phosphate isomerase A	-
HCM98_RS12890 (HCM98_12910)	-	2484212..2484532 (-)	321	WP_029438605.1	2Fe-2S iron-sulfur cluster-binding protein	-
HCM98_RS12895 (HCM98_12915)	-	2484676..2485362 (+)	687	WP_029438604.1	RNA polymerase subunit sigma-70	-
HCM98_RS12900 (HCM98_12920)	clpP	2485384..2485965 (+)	582	WP_000991609.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
HCM98_RS12905 (HCM98_12925)	-	2486012..2486869 (-)	858	WP_029438603.1	glycine betaine ABC transporter substrate-binding protein	-
HCM98_RS12910 (HCM98_12930)	-	2487041..2488246 (+)	1206	WP_029438602.1	glycine betaine/L-proline ABC transporter ATP-binding protein	-
HCM98_RS12915 (HCM98_12935)	-	2488239..2489075 (+)	837	WP_029438601.1	proline/glycine betaine ABC transporter permease	-
HCM98_RS12920 (HCM98_12940)	-	2489126..2489362 (-)	237	WP_029438600.1	hypothetical protein	-
HCM98_RS12925 (HCM98_12945)	-	2489580..2489744 (+)	165	WP_029438599.1	hypothetical protein	-
HCM98_RS12930 (HCM98_12950)	-	2489845..2490336 (+)	492	WP_061686514.1	HIT family protein	-

Sequence

Protein

• Length: 193 a.a.
• Molecular weight: 21192.49 Da
• Isoelectric Point: 5.3394

>NTDB_id=436066 HCM98_RS12900 WP_000991609.1 2485384..2485965(+) (clpP) [Bacillus tropicus strain LM1212-DB]
MNAIPYVVEQTKLGERSYDIYSRLLKDRIIIIGSEINDQVASSVVAQLLFLEAEDAEKDIFLYINSPGGSTTAGFAILDT
MNLIKPDVQTLCMGFAASFGALLLLSGAKGKRFALPNSEIMIHQPLGGAKGQATEIEITAKRILKLKHDINKMIAEKTGQ
PIERVAHDTERDYFMTAEEAKAYGIVDDVVTKK

Nucleotide

• Length: 582 bp

>NTDB_id=436066 HCM98_RS12900 WP_000991609.1 2485384..2485965(+) (clpP) [Bacillus tropicus strain LM1212-DB]
ATGAATGCAATTCCATATGTTGTAGAACAAACAAAATTAGGAGAACGTTCCTATGATATATATTCAAGGTTATTAAAAGA
CCGTATTATTATTATCGGTTCAGAAATAAATGATCAAGTAGCGAGTAGTGTCGTAGCTCAATTATTATTTTTAGAAGCAG
AAGATGCAGAGAAAGATATATTTTTATACATTAATAGCCCCGGCGGATCAACGACAGCGGGATTTGCTATATTAGATACA
ATGAATTTAATCAAACCTGATGTGCAAACGCTATGCATGGGCTTTGCAGCATCATTTGGTGCATTGTTATTATTATCAGG
TGCAAAAGGAAAACGATTTGCACTCCCAAATAGTGAAATTATGATTCATCAGCCACTTGGTGGTGCAAAAGGGCAAGCAA
CAGAAATTGAAATAACAGCAAAAAGGATATTAAAGTTAAAGCATGATATTAATAAAATGATTGCAGAAAAAACGGGGCAA
CCGATTGAAAGAGTAGCACATGATACAGAAAGAGATTATTTTATGACCGCAGAAGAAGCAAAGGCATATGGGATTGTAGA
TGATGTTGTTACGAAAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (14-192)

3D structure

• AlphaFold DB: A0A853X8N5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	68.063	98.964	0.674
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	67.196	97.927	0.658
clpP	Streptococcus pyogenes JRS4	56.085	97.927	0.549
clpP	Streptococcus pyogenes MGAS315	56.085	97.927	0.549
clpP	Streptococcus pneumoniae R6	55.208	99.482	0.549
clpP	Streptococcus pneumoniae TIGR4	55.208	99.482	0.549
clpP	Streptococcus pneumoniae Rx1	55.208	99.482	0.549
clpP	Streptococcus thermophilus LMG 18311	55.208	99.482	0.549
clpP	Streptococcus thermophilus LMD-9	55.208	99.482	0.549
clpP	Streptococcus pneumoniae D39	55.208	99.482	0.549
clpP	Streptococcus mutans UA159	53.968	97.927	0.528
clpP	Lactococcus lactis subsp. cremoris KW2	51.852	97.927	0.508
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	50.265	97.927	0.492