Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   SMUGS5_RS02825 Genome accession   NC_018089
Coordinates   573835..574515 (+) Length   226 a.a.
NCBI ID   WP_002269714.1    Uniprot ID   -
Organism   Streptococcus mutans GS-5     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 568835..579515
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUGS5_RS02805 (SMUGS5_02715) - 570207..571226 (-) 1020 WP_002267101.1 GIY-YIG nuclease family protein -
  SMUGS5_RS02810 (SMUGS5_02720) - 571272..571784 (-) 513 WP_002261919.1 HXXEE domain-containing protein -
  SMUGS5_RS02815 (SMUGS5_02725) - 571869..572804 (-) 936 WP_014834886.1 polysaccharide deacetylase family protein -
  SMUGS5_RS02820 (SMUGS5_02730) - 572943..573695 (+) 753 WP_002261917.1 lysophospholipid acyltransferase family protein -
  SMUGS5_RS02825 (SMUGS5_02735) comEA/celA/cilE 573835..574515 (+) 681 WP_002269714.1 helix-hairpin-helix domain-containing protein Machinery gene
  SMUGS5_RS02830 (SMUGS5_02740) comEC/celB 574505..576739 (+) 2235 WP_002267862.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  SMUGS5_RS02835 (SMUGS5_02745) - 576925..577551 (+) 627 WP_002264731.1 DUF805 domain-containing protein -
  SMUGS5_RS02840 (SMUGS5_02750) holA 577719..578759 (+) 1041 WP_002264730.1 DNA polymerase III subunit delta -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24589.91 Da        Isoelectric Point: 7.0283

>NTDB_id=43507 SMUGS5_RS02825 WP_002269714.1 573835..574515(+) (comEA/celA/cilE) [Streptococcus mutans GS-5]
MVDEFLDKLKEKKNVFTLVGGLVVLLGLGVYFFFPSSNKQEDSLARLKEQSLQVTTKTGKESQKKTQVTTAKSTITVDIK
GAVKHEGVYTLPIDSRIDDVIEKAGGFSEKADRKSVNLAQKLQDEAVIYVAAIGENISVIRDSQEGKTSQADKANTKETS
VKGKVNLNTATLADLQTISGIGEKKAQDILDYREANGGFKSVDDLKNISGIGDKTFEKLKDLVSVD

Nucleotide


Download         Length: 681 bp        

>NTDB_id=43507 SMUGS5_RS02825 WP_002269714.1 573835..574515(+) (comEA/celA/cilE) [Streptococcus mutans GS-5]
ATGGTTGACGAATTTTTAGATAAACTCAAGGAAAAGAAAAATGTTTTTACCCTAGTTGGTGGTCTTGTAGTCTTACTGGG
TCTGGGTGTTTATTTCTTTTTTCCTTCTTCCAATAAGCAGGAAGATAGTCTGGCTCGTTTAAAGGAACAATCCCTTCAGG
TAACCACAAAGACTGGCAAAGAAAGTCAGAAGAAGACGCAGGTGACGACTGCCAAATCAACAATAACTGTTGATATTAAA
GGAGCTGTTAAGCATGAGGGCGTCTATACTTTACCGATTGACAGTCGTATTGATGATGTGATAGAAAAAGCGGGAGGTTT
TTCTGAAAAGGCTGATCGCAAATCTGTTAATCTGGCTCAAAAATTACAAGACGAAGCAGTTATTTATGTGGCAGCTATTG
GTGAGAATATTAGTGTCATTAGGGATTCTCAAGAAGGTAAAACCAGTCAGGCAGATAAGGCAAATACTAAAGAAACTTCG
GTAAAAGGTAAGGTTAATCTTAATACTGCCACTTTGGCTGATTTACAGACTATTTCTGGAATCGGTGAGAAGAAAGCTCA
GGATATTCTTGATTACCGTGAAGCCAATGGAGGTTTTAAGTCAGTGGATGATTTGAAAAATATTTCAGGGATTGGCGATA
AAACATTTGAGAAGTTAAAGGATTTAGTCAGTGTTGATTAG

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(163-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

42.06

100

0.434
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

41.631

100

0.429
  comEA/celA/cilE Streptococcus mitis SK321

41.81

100

0.429
  comEA/celA/cilE Streptococcus pneumoniae D39

41.202

100

0.425
  comEA/celA/cilE Streptococcus pneumoniae Rx1

41.202

100

0.425
  comEA/celA/cilE Streptococcus pneumoniae R6

41.202

100

0.425
  comEA Lactococcus lactis subsp. cremoris KW2

42.478

100

0.425
  comEA Streptococcus thermophilus LMD-9

57.143

68.142

0.389
  comEA Latilactobacillus sakei subsp. sakei 23K

35.537

100

0.381

Multiple sequence alignment