Detailed information NTG0435017

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: IMP90_RS04880
• Genome accession: NZ_CP062865
• Coordinates: 1032569..1033192 (+)
• Length: 207 a.a.
• NCBI ID: WP_000122253.1
• Uniprot ID: A0A370V1H3
• Organism: Escherichia coli O39:H21 strain Res13-Lact-PEB08-01
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1027569..1038192

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IMP90_RS04860 (IMP90_04855)	ampG	1027962..1029437 (-)	1476	WP_000098438.1	muropeptide MFS transporter AmpG	-
IMP90_RS04865 (IMP90_04860)	yajG	1029481..1030059 (-)	579	WP_001295326.1	lipoprotein	-
IMP90_RS04870 (IMP90_04865)	bolA	1030364..1030681 (+)	318	WP_000973448.1	transcriptional regulator BolA	-
IMP90_RS04875 (IMP90_04870)	tig	1031025..1032323 (+)	1299	WP_001198386.1	trigger factor	-
IMP90_RS04880 (IMP90_04875)	clpP	1032569..1033192 (+)	624	WP_000122253.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
IMP90_RS04885 (IMP90_04880)	clpX	1033318..1034592 (+)	1275	WP_000130305.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
IMP90_RS04890 (IMP90_04885)	lon	1034780..1037134 (+)	2355	WP_001295325.1	endopeptidase La	-
IMP90_RS04895 (IMP90_04890)	hupB	1037343..1037615 (+)	273	WP_001043542.1	nucleoid-associated protein HU-beta	-

Sequence

Protein

• Length: 207 a.a.
• Molecular weight: 23186.65 Da
• Isoelectric Point: 5.6032

>NTDB_id=435017 IMP90_RS04880 WP_000122253.1 1032569..1033192(+) (clpP) [Escherichia coli O39:H21 strain Res13-Lact-PEB08-01]
MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIFLTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSP
GGVITAGMSIYDTMQFIKPDVSTICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVK
GRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN

Nucleotide

• Length: 624 bp

>NTDB_id=435017 IMP90_RS04880 WP_000122253.1 1032569..1033192(+) (clpP) [Escherichia coli O39:H21 strain Res13-Lact-PEB08-01]
ATGTCATACAGCGGCGAACGAGATAACTTTGCACCCCATATGGCGCTGGTGCCGATGGTCATTGAACAGACCTCACGCGG
TGAGCGCTCTTTTGATATCTATTCTCGTCTACTTAAGGAACGCGTCATTTTTCTGACTGGCCAGGTTGAAGACCACATGG
CTAACCTGATTGTGGCGCAGATGCTGTTCCTGGAAGCGGAAAACCCAGAAAAAGATATCTATCTGTACATTAACTCCCCA
GGCGGGGTGATCACTGCCGGGATGTCTATCTATGACACCATGCAGTTTATCAAGCCTGATGTCAGCACCATCTGTATGGG
CCAGGCGGCCTCGATGGGCGCTTTCTTGTTGACCGCAGGGGCAAAAGGTAAACGTTTTTGCCTGCCGAATTCGCGCGTGA
TGATTCACCAACCGTTGGGCGGCTACCAGGGCCAGGCGACCGATATCGAAATTCATGCCCGTGAAATTCTGAAAGTTAAA
GGGCGCATGAATGAACTTATGGCGCTTCATACGGGTCAATCATTAGAACAGATTGAACGTGATACCGAGCGCGATCGCTT
CCTTTCCGCCCCTGAAGCGGTGGAATACGGTCTGGTCGATTCGATTCTGACCCATCGTAATTGA

Domains

Predicted by InterProScan.

• Clp protease (CLP_protease) (26-205)

3D structure

• AlphaFold DB: A0A370V1H3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	69.792	92.754	0.647
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	90.821	0.623
clpP	Lactococcus lactis subsp. cremoris KW2	56.701	93.72	0.531
clpP	Streptococcus pneumoniae R6	55.155	93.72	0.517
clpP	Streptococcus pneumoniae TIGR4	55.155	93.72	0.517
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.155	93.72	0.517
clpP	Streptococcus pneumoniae Rx1	55.155	93.72	0.517
clpP	Streptococcus pneumoniae D39	55.155	93.72	0.517
clpP	Streptococcus thermophilus LMD-9	54.922	93.237	0.512
clpP	Streptococcus thermophilus LMG 18311	54.922	93.237	0.512
clpP	Streptococcus pyogenes JRS4	55.263	91.787	0.507
clpP	Streptococcus pyogenes MGAS315	55.263	91.787	0.507
clpP	Streptococcus mutans UA159	53.886	93.237	0.502