Detailed information NTG0431121

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: HB752_RS04730
• Genome accession: NZ_CP050271
• Coordinates: 938458..939300 (-)
• Length: 280 a.a.
• NCBI ID: WP_002262865.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain S1
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 933458..944300

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HB752_RS04720 (HB752_04720)	trmFO	934547..935881 (-)	1335	WP_019804769.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
HB752_RS04725 (HB752_04725)	topA	936246..938363 (-)	2118	WP_002272153.1	type I DNA topoisomerase	-
HB752_RS04730 (HB752_04730)	dprA	938458..939300 (-)	843	WP_002262865.1	DNA-processing protein DprA	Machinery gene
HB752_RS04735 (HB752_04735)	-	939467..939748 (-)	282	WP_002285184.1	hypothetical protein	-
HB752_RS04740 (HB752_04740)	-	939820..940836 (-)	1017	WP_002305237.1	siderophore ABC transporter substrate-binding protein	-
HB752_RS04745 (HB752_04745)	-	940884..941690 (-)	807	WP_002270389.1	ATP-binding cassette domain-containing protein	-
HB752_RS04750 (HB752_04750)	-	941687..942658 (-)	972	WP_002275899.1	iron chelate uptake ABC transporter family permease subunit	-
HB752_RS04755 (HB752_04755)	-	942655..943617 (-)	963	WP_002270387.1	iron chelate uptake ABC transporter family permease subunit	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31332.27 Da
• Isoelectric Point: 9.1954

>NTDB_id=431121 HB752_RS04730 WP_002262865.1 938458..939300(-) (dprA) [Streptococcus mutans strain S1]
MDNFQLFKLKKAGLTNLNILNIIDYEERTQKSLSLRDMAVVSKNKKPLIFMEHYKNLDSKALRKEFNRFPSLSILDKEYP
LELKNIYNPPVLLFYQGDLDLLARPKLAVVGSRNASQMGVAAVKKIIQDLSKQFVIISGLARGIDTAAHLASLKSGGATI
AVIGTGLDVHYPKENRRLQDYIAKNHLLLSEYEAQSQPLKYHFPERNRIIAGLSQGVMVAEAKIRSGSLITCERAMEEGR
DVFVVPGNILDGQSEGCHHLIQEGAKCITSGFDILNEFNF

Nucleotide

• Length: 843 bp

>NTDB_id=431121 HB752_RS04730 WP_002262865.1 938458..939300(-) (dprA) [Streptococcus mutans strain S1]
ATGGATAATTTTCAACTATTTAAACTTAAAAAAGCTGGTCTAACAAATCTGAATATCTTAAATATTATTGATTATGAAGA
GAGGACACAAAAATCCTTGTCTCTTCGTGATATGGCTGTTGTTTCCAAAAATAAAAAGCCTTTAATTTTTATGGAACATT
ACAAGAATCTTGATAGCAAAGCATTACGCAAAGAATTTAATCGTTTTCCTTCTTTATCCATTTTGGACAAAGAATATCCC
TTGGAACTTAAAAATATTTATAATCCGCCTGTTCTTCTATTTTATCAGGGAGACTTAGACTTGCTAGCTCGGCCTAAATT
AGCAGTAGTTGGTTCTCGCAACGCCAGTCAAATGGGAGTAGCTGCTGTTAAAAAGATCATACAAGACTTAAGTAAGCAAT
TTGTTATTATTAGCGGTTTAGCTCGTGGTATTGATACTGCAGCACATTTAGCAAGTCTTAAAAGCGGTGGAGCAACAATT
GCGGTCATCGGTACTGGACTAGATGTTCATTATCCTAAAGAAAATCGAAGACTGCAGGATTATATTGCAAAGAATCATTT
GCTCTTATCAGAATATGAAGCACAGAGTCAACCTCTTAAGTATCATTTTCCTGAGCGGAACCGCATTATTGCTGGGTTAT
CTCAAGGTGTTATGGTAGCAGAAGCAAAAATTCGTTCGGGTAGTCTGATTACTTGTGAACGTGCTATGGAAGAAGGACGC
GATGTTTTTGTTGTACCAGGAAATATTTTAGACGGCCAGTCAGAAGGATGCCATCACCTGATTCAAGAAGGAGCAAAATG
CATTACATCAGGCTTTGATATTTTAAATGAGTTTAACTTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (72-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	100	100	1
dprA/cilB/dalA	Streptococcus mitis SK321	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae D39	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae R6	63.214	100	0.632
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	63.214	100	0.632
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	62.857	100	0.629
dprA	Lactococcus lactis subsp. cremoris KW2	58.273	99.286	0.579
dprA	Legionella pneumophila strain ERS1305867	44.77	85.357	0.382
dprA	Staphylococcus aureus N315	38.258	94.286	0.361