Detailed information NTG0431108

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: HB752_RS01810
• Genome accession: NZ_CP050271
• Coordinates: 347355..347945 (+)
• Length: 196 a.a.
• NCBI ID: WP_002264033.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain S1
• Function: degradation of ComX; require for competence development (at the early growth phase); repress competence development (at the mid-logarithmic growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 342355..352945

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HB752_RS01795 (HB752_01795)	-	343509..344603 (+)	1095	WP_002268067.1	cystathionine gamma-synthase	-
HB752_RS01800 (HB752_01800)	-	344618..345781 (+)	1164	WP_002271035.1	MalY/PatB family protein	-
HB752_RS01805 (HB752_01805)	upp	346094..346723 (+)	630	WP_002262598.1	uracil phosphoribosyltransferase	-
HB752_RS01810 (HB752_01810)	clpP	347355..347945 (+)	591	WP_002264033.1	ATP-dependent Clp protease proteolytic subunit ClpP	Regulator
HB752_RS01815 (HB752_01815)	-	348060..348500 (+)	441	WP_002275751.1	YlbF family regulator	-
HB752_RS01820 (HB752_01820)	-	348507..348755 (+)	249	WP_002262674.1	YlbG family protein	-
HB752_RS01825 (HB752_01825)	-	348858..350030 (+)	1173	WP_002264030.1	ABC transporter substrate-binding protein	-
HB752_RS01830 (HB752_01830)	-	350114..350983 (+)	870	WP_002262676.1	branched-chain amino acid ABC transporter permease	-
HB752_RS01835 (HB752_01835)	-	350987..351943 (+)	957	WP_002266832.1	branched-chain amino acid ABC transporter permease	-
HB752_RS01840 (HB752_01840)	-	351943..352707 (+)	765	WP_002262678.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21655.92 Da
• Isoelectric Point: 5.3292

>NTDB_id=431108 HB752_RS01810 WP_002264033.1 347355..347945(+) (clpP) [Streptococcus mutans strain S1]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDNTKDIYLYINSPGGSVSAGLAIVDTMN
FIKSDVQTIVMGIAASMGTIIASSGAKGKRFMLPNAEYLIHQPMGGTGGGTQQSDMAIAAEQLLKTRKKLEKILSDNSGK
TVKQIHKDAERDYWMDAKETLKYGFIDEIMENNELK

Nucleotide

• Length: 591 bp

>NTDB_id=431108 HB752_RS01810 WP_002264033.1 347355..347945(+) (clpP) [Streptococcus mutans strain S1]
ATGATTCCTGTAGTTATTGAACAAACGAGCCGTGGTGAACGCTCTTATGATATTTATTCACGTCTATTAAAAGATCGTAT
TATTATGTTGACTGGTCCTGTTGAAGACAATATGGCAAATTCCATTATTGCTCAGTTACTGTTTCTTGATGCACAAGATA
ATACCAAAGACATTTATCTTTATATTAATTCACCGGGTGGTTCTGTTTCAGCTGGTCTTGCTATTGTTGATACGATGAAC
TTTATTAAGTCTGATGTTCAAACGATTGTTATGGGTATTGCTGCTTCCATGGGAACAATCATCGCTTCTAGCGGTGCCAA
AGGAAAACGTTTTATGTTACCAAATGCAGAATATCTTATCCATCAGCCAATGGGCGGTACAGGCGGTGGCACACAGCAGT
CTGATATGGCTATTGCTGCCGAACAATTGCTTAAAACACGCAAAAAATTAGAAAAGATTCTATCGGATAATTCTGGAAAA
ACAGTAAAACAAATTCATAAGGATGCTGAACGTGATTATTGGATGGATGCTAAGGAAACATTAAAGTATGGCTTCATCGA
TGAAATCATGGAAAATAATGAATTAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus mutans UA159	99.49	100	0.995
clpP	Streptococcus pyogenes JRS4	90.306	100	0.903
clpP	Streptococcus pyogenes MGAS315	90.306	100	0.903
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	87.755	100	0.878
clpP	Streptococcus thermophilus LMD-9	87.245	100	0.872
clpP	Lactococcus lactis subsp. cremoris KW2	87.245	100	0.872
clpP	Streptococcus thermophilus LMG 18311	87.245	100	0.872
clpP	Streptococcus pneumoniae Rx1	86.154	99.49	0.857
clpP	Streptococcus pneumoniae D39	86.154	99.49	0.857
clpP	Streptococcus pneumoniae R6	86.154	99.49	0.857
clpP	Streptococcus pneumoniae TIGR4	86.154	99.49	0.857
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	57.513	98.469	0.566
clpP	Bacillus subtilis subsp. subtilis str. 168	56.122	100	0.561