Detailed information NTG0430236

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: HBA50_RS08420
• Genome accession: NZ_CP050133
• Coordinates: 1696517..1698670 (-)
• Length: 717 a.a.
• NCBI ID: WP_045498536.1
• Uniprot ID: -
• Organism: Streptococcus cristatus ATCC 51100
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1691517..1703670

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HBA50_RS08390 (HBA50_08390)	ccrZ	1691664..1692458 (-)	795	WP_005591081.1	cell cycle regulator CcrZ	-
HBA50_RS08395 (HBA50_08395)	-	1692509..1693555 (-)	1047	WP_045498541.1	ABC transporter permease	-
HBA50_RS08400 (HBA50_08400)	pptA	1693552..1694283 (-)	732	WP_005591084.1	ABC transporter ATP-binding protein	Regulator
HBA50_RS08405 (HBA50_08405)	-	1694351..1694761 (+)	411	WP_005591086.1	HIT family protein	-
HBA50_RS08410 (HBA50_08410)	-	1694771..1695046 (+)	276	WP_005591088.1	hypothetical protein	-
HBA50_RS08415 (HBA50_08415)	comB	1695147..1696502 (-)	1356	WP_045498538.1	bacteriocin secretion accessory protein	Regulator
HBA50_RS08420 (HBA50_08420)	comA	1696517..1698670 (-)	2154	WP_045498536.1	peptide cleavage/export ABC transporter ComA	Regulator
HBA50_RS08425 (HBA50_08425)	-	1699022..1699246 (-)	225	WP_235285264.1	hypothetical protein	-
HBA50_RS08430 (HBA50_08430)	-	1699315..1699488 (-)	174	WP_005592399.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
HBA50_RS08435 (HBA50_08435)	rnhC	1699714..1700598 (+)	885	WP_045498529.1	ribonuclease HIII	-
HBA50_RS08440 (HBA50_08440)	lepB	1700602..1701234 (+)	633	WP_045498526.1	signal peptidase I	-
HBA50_RS08445 (HBA50_08445)	-	1701310..1703670 (+)	2361	WP_045498523.1	ATP-dependent RecD-like DNA helicase	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 81187.61 Da
• Isoelectric Point: 8.0275

>NTDB_id=430236 HBA50_RS08420 WP_045498536.1 1696517..1698670(-) (comA) [Streptococcus cristatus ATCC 51100]
MRFTKRHYRAQVDARDCGVAALAMIYGYYGSYYSLASLREMAKTTLRGTTAFGLVKVSEELGFETRAFKADMSLFDMKGI
VYPFIAHVIKDKKLLHYYVVTGHDKHSVYIADPDPAVKMTKLSKEQFAQEWTGVSIFIAPAPEYRPHKEKKNGLWSFVPI
LMKQKGLIANIVIATMLVTIINIVGSYYMQGIIDTYVPNQMRNTLGIISLGLIVVYILQQVLTYAQSYLLLILGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFNDANSIIDALASTILSIFLDVSIVVVMAIVLFSQNFYLFFISLLSLPIYIV
VIFAFMKPFEKMNRDTMESNAILSSSIIEDINGIETIKSLTSEDFRYQKIDREFVDYLKKSFTYSRMENIQIGLKKTAQL
LLNVAILWMGALLVMDNKMTLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVDSEFMDKKAIRDLSMT
KGDIELRNVSYKYGYGRNVLSDINLTIERGSKVAFVGISGSGKTTLAKMIVNFYDPNEGEILVNNINLNQIDKHVLRRHI
NYLPQQPYVFNGTILENVLLGAKPGTTQKEIIRALEIAEIREDIERMPLNYQTELTSDGSGISGGQRQRLALARALLTDA
PVLILDEATSNLDILTEKKIIDNLLELDKTIIFIAHRLTIAERSEKVVVLDKGEIVEQGTHEELVAQDGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=430236 HBA50_RS08420 WP_045498536.1 1696517..1698670(-) (comA) [Streptococcus cristatus ATCC 51100]
ATGAGATTTACAAAGCGTCATTATAGGGCTCAAGTTGACGCGAGAGATTGTGGTGTAGCAGCGCTGGCCATGATATATGG
CTATTATGGTTCCTATTATTCTTTGGCTAGTTTGCGTGAAATGGCCAAGACAACTTTAAGAGGAACAACTGCTTTTGGGC
TAGTGAAGGTTTCGGAAGAGTTAGGTTTTGAAACACGAGCCTTTAAAGCGGATATGTCTTTATTTGACATGAAGGGCATC
GTTTATCCTTTTATCGCCCATGTTATCAAAGACAAGAAATTGCTTCACTATTATGTTGTGACTGGGCACGATAAACATTC
GGTTTATATTGCGGATCCAGATCCGGCTGTTAAAATGACCAAGCTTTCTAAGGAACAGTTTGCGCAAGAGTGGACAGGTG
TCTCTATTTTCATCGCCCCAGCGCCAGAATATAGACCACACAAGGAAAAGAAAAACGGTCTCTGGTCTTTTGTTCCGATT
TTAATGAAACAAAAGGGACTGATTGCCAATATCGTTATTGCAACGATGCTGGTGACGATTATCAATATCGTGGGCTCTTA
CTACATGCAGGGGATTATTGATACTTACGTACCGAATCAGATGAGGAATACCTTAGGAATTATTTCTCTCGGTCTAATAG
TTGTCTACATTTTGCAACAGGTCCTAACTTATGCTCAGAGCTATCTGCTTCTTATTTTAGGCCAACGCCTTTCGATTGAT
GTGATTTTGTCCTATATTAAGCATGTCTTTCATCTACCGATGTCTTTTTTTGCGACGAGAAGGACAGGGGAAATCGTATC
GCGCTTCAACGATGCCAATAGTATCATTGATGCCTTGGCCAGCACCATTCTGTCCATCTTTTTGGATGTCTCTATCGTTG
TCGTTATGGCAATTGTTTTGTTCTCACAAAACTTCTATTTGTTCTTTATCAGTTTGCTCTCGCTGCCAATCTATATCGTC
GTGATTTTTGCCTTCATGAAGCCATTTGAAAAAATGAATCGCGATACGATGGAATCCAATGCCATCCTGTCTTCTTCCAT
TATCGAAGATATCAATGGTATTGAGACGATCAAATCCTTGACAAGTGAAGATTTCCGCTATCAAAAAATTGATAGAGAAT
TTGTTGACTATCTAAAGAAATCATTTACTTATAGTCGAATGGAGAATATCCAAATCGGTTTGAAGAAGACGGCTCAGCTC
TTGCTGAATGTTGCAATCCTTTGGATGGGAGCTCTTTTGGTAATGGACAATAAAATGACCTTGGGGCAGTTGATTACTTA
TAATACTTTGTTGGTTTATTTCACAAATCCGCTGGAAAATATTATCAATTTACAGACCAAGCTTCAGACTGCACAAGTTG
CCAATAATCGCTTGAACGAGGTTTATCTGGTTGACTCTGAATTTATGGATAAAAAAGCGATCCGTGATTTGAGCATGACC
AAGGGCGACATTGAGTTGAGAAATGTCAGCTACAAGTATGGCTATGGACGAAACGTTCTGTCGGATATTAATTTGACCAT
TGAAAGAGGCAGCAAGGTGGCCTTTGTAGGAATTTCTGGTTCTGGAAAGACGACTCTTGCCAAGATGATCGTGAACTTTT
ACGATCCAAACGAGGGAGAAATTCTGGTTAATAATATCAACCTCAATCAGATTGACAAGCATGTCTTGCGCCGTCATATC
AATTACTTGCCGCAACAGCCTTATGTTTTTAATGGTACCATCTTGGAGAATGTTCTCCTAGGTGCCAAGCCCGGAACGAC
TCAGAAAGAAATCATTCGGGCGTTGGAAATTGCAGAAATTCGTGAAGATATTGAACGGATGCCTTTGAATTACCAAACAG
AATTGACATCGGATGGTTCAGGAATTTCAGGTGGTCAGCGTCAGCGCTTGGCCTTGGCTCGGGCTCTTTTGACAGATGCT
CCTGTTTTGATCCTTGATGAGGCGACCAGCAATCTGGATATCTTGACAGAGAAAAAGATTATTGACAACCTTTTGGAGTT
GGACAAGACCATTATTTTCATTGCCCATCGATTGACCATTGCGGAGCGATCTGAAAAAGTGGTTGTTCTGGACAAGGGTG
AAATCGTGGAGCAAGGAACACATGAAGAGTTGGTTGCTCAGGATGGCTTCTATGCTCATCTGGTGAATAGTTAG

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter (ABC_tran) (500-650)

• ABC transporter transmembrane region (ABC_membrane) (170-438)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	79.777	100	0.798
comA	Streptococcus pneumoniae Rx1	79.498	100	0.795
comA	Streptococcus pneumoniae D39	79.498	100	0.795
comA	Streptococcus pneumoniae R6	79.498	100	0.795
comA	Streptococcus mitis SK321	79.358	100	0.794
comA	Streptococcus pneumoniae TIGR4	79.219	100	0.792
comA	Streptococcus gordonii str. Challis substr. CH1	76.151	100	0.762
comA/nlmT	Streptococcus mutans UA159	63.877	100	0.639