Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   HBA50_RS08415 Genome accession   NZ_CP050133
Coordinates   1695147..1696502 (-) Length   451 a.a.
NCBI ID   WP_045498538.1    Uniprot ID   -
Organism   Streptococcus cristatus ATCC 51100     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1690147..1701502
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HBA50_RS08385 (HBA50_08385) trmB 1691029..1691667 (-) 639 WP_045498545.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -
  HBA50_RS08390 (HBA50_08390) ccrZ 1691664..1692458 (-) 795 WP_005591081.1 cell cycle regulator CcrZ -
  HBA50_RS08395 (HBA50_08395) - 1692509..1693555 (-) 1047 WP_045498541.1 ABC transporter permease -
  HBA50_RS08400 (HBA50_08400) pptA 1693552..1694283 (-) 732 WP_005591084.1 ABC transporter ATP-binding protein Regulator
  HBA50_RS08405 (HBA50_08405) - 1694351..1694761 (+) 411 WP_005591086.1 HIT family protein -
  HBA50_RS08410 (HBA50_08410) - 1694771..1695046 (+) 276 WP_005591088.1 hypothetical protein -
  HBA50_RS08415 (HBA50_08415) comB 1695147..1696502 (-) 1356 WP_045498538.1 bacteriocin secretion accessory protein Regulator
  HBA50_RS08420 (HBA50_08420) comA 1696517..1698670 (-) 2154 WP_045498536.1 peptide cleavage/export ABC transporter ComA Regulator
  HBA50_RS08425 (HBA50_08425) - 1699022..1699246 (-) 225 WP_235285264.1 hypothetical protein -
  HBA50_RS08430 (HBA50_08430) - 1699315..1699488 (-) 174 WP_005592399.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  HBA50_RS08435 (HBA50_08435) rnhC 1699714..1700598 (+) 885 WP_045498529.1 ribonuclease HIII -
  HBA50_RS08440 (HBA50_08440) lepB 1700602..1701234 (+) 633 WP_045498526.1 signal peptidase I -

Sequence

Protein


Download         Length: 451 a.a.        Molecular weight: 49850.77 Da        Isoelectric Point: 6.5449

>NTDB_id=430235 HBA50_RS08415 WP_045498538.1 1695147..1696502(-) (comB) [Streptococcus cristatus ATCC 51100]
MEEHYLESAEFYNRRYSSFSVRVILPTFFLLIFVVLFSLFAKKEITITSGASIEPSKILANIQSTSNNAIVTNNLKENKV
VKKGDLLVQYKSDSENTQKETFSSQVESLKEQKRQLELLQESLKTGTSQFSGEDRFGYEQAFNDYKNQAASIRSNTEQQN
STIASQNSAASNSQAELGNLINETNAKLADYQTLRNAIQNGTSVPSTNAGYSIYQAYEAQAAADSQGQLKSQVLSQIDNQ
ISQFESALSGYRVQYAGSGAQQAYSGSLDSQLESLKAQQLTKVGQELTALNQKILEVENNLKVQGGITQKGVITATEDGI
LHLNPETAGANLVPEGKLLAQLYPVLTKEKKVVITTYVTSKDVASLKKGETLRFTAMDGNNKEFVLKSKISNIDNNATKT
EKGNFFKVEAEISLTDAQAKKIRYGIEGRAVVITGSKTYFDYYLDQFLRKD

Nucleotide


Download         Length: 1356 bp        

>NTDB_id=430235 HBA50_RS08415 WP_045498538.1 1695147..1696502(-) (comB) [Streptococcus cristatus ATCC 51100]
ATGGAAGAACATTACTTAGAGAGTGCCGAATTTTATAACCGTAGATATTCTAGCTTTTCTGTGCGCGTGATTTTACCGAC
TTTCTTCTTGTTGATTTTTGTGGTCTTATTCTCCCTCTTTGCTAAAAAAGAAATCACTATTACTTCAGGTGCTTCTATTG
AACCTAGCAAGATTCTGGCTAACATCCAATCAACCAGTAACAATGCCATTGTCACTAATAATTTGAAGGAAAACAAGGTT
GTTAAAAAAGGGGATCTTTTAGTTCAGTATAAGTCTGATAGCGAAAATACTCAAAAAGAAACCTTCTCCTCTCAAGTAGA
AAGCTTGAAGGAGCAAAAACGTCAGTTGGAGCTGCTGCAAGAAAGTCTGAAGACGGGGACTAGCCAGTTTTCAGGAGAGG
ATCGCTTCGGCTATGAGCAAGCATTTAATGATTATAAGAACCAAGCTGCGAGTATCCGTAGTAATACCGAACAGCAAAAT
TCGACCATTGCTTCTCAAAATTCAGCAGCTAGCAATTCACAAGCAGAGCTGGGGAATCTGATCAATGAAACAAATGCCAA
ATTAGCAGATTATCAGACCCTTAGAAATGCTATCCAAAATGGGACAAGTGTCCCTTCGACTAATGCTGGTTATAGCATTT
ATCAGGCTTATGAGGCGCAAGCTGCTGCTGATAGTCAAGGTCAGCTAAAGAGTCAAGTTCTGTCGCAGATTGACAATCAG
ATTTCCCAGTTTGAATCAGCTCTTTCGGGCTATCGAGTGCAGTATGCAGGTTCCGGTGCTCAGCAAGCCTATTCTGGTAG
CTTGGATAGCCAGCTTGAGTCTTTGAAAGCTCAGCAGTTGACTAAAGTTGGTCAAGAATTGACGGCCTTGAATCAAAAGA
TTTTAGAAGTTGAAAACAATCTCAAGGTGCAAGGTGGTATTACTCAAAAGGGCGTGATCACAGCAACTGAAGATGGTATT
CTCCACCTAAATCCTGAAACAGCAGGAGCGAATCTGGTTCCTGAAGGGAAGTTGCTTGCTCAATTGTATCCTGTTTTGAC
CAAGGAAAAAAAGGTCGTTATCACAACCTATGTGACCTCAAAAGATGTTGCTAGTCTGAAAAAAGGTGAGACTCTGCGTT
TCACTGCAATGGATGGAAATAATAAAGAATTTGTTCTCAAATCTAAAATTTCAAACATTGACAACAATGCGACGAAAACG
GAAAAAGGCAACTTCTTTAAGGTTGAAGCTGAAATAAGCTTAACGGATGCCCAAGCCAAGAAGATACGTTATGGTATTGA
AGGTCGTGCAGTAGTCATCACAGGAAGCAAAACTTACTTTGACTATTACTTGGATCAATTCTTGAGAAAGGACTAA

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(312-425)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mitis SK321

57.206

100

0.572
  comB Streptococcus pneumoniae Rx1

56.984

100

0.57
  comB Streptococcus pneumoniae D39

56.984

100

0.57
  comB Streptococcus pneumoniae R6

56.984

100

0.57
  comB Streptococcus mitis NCTC 12261

56.984

100

0.57
  comB Streptococcus pneumoniae TIGR4

56.541

100

0.565
  comB Streptococcus gordonii str. Challis substr. CH1

54.12

99.557

0.539