Detailed information
Bioinformatically predicted
Overview
| Name | prx | Type | Regulator |
| Locus tag | G8B35_RS03405 | Genome accession | NZ_CP049697 |
| Coordinates | 659055..659237 (+) | Length | 60 a.a. |
| NCBI ID | WP_011528776.1 | Uniprot ID | A0A660A5W9 |
| Organism | Streptococcus pyogenes strain ABC3 | ||
| Function | Inhibit ComR activation (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 623571..659237 | 659055..659237 | within | 0 |
Gene organization within MGE regions
Location: 623571..659237
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| G8B35_RS03140 (G8B35_03150) | - | 623571..623846 (+) | 276 | WP_002983920.1 | HU family DNA-binding protein | - |
| G8B35_RS03145 (G8B35_03155) | - | 623935..625077 (-) | 1143 | WP_003051793.1 | site-specific integrase | - |
| G8B35_RS03150 (G8B35_03160) | - | 625201..625719 (-) | 519 | WP_011528799.1 | HIRAN domain-containing protein | - |
| G8B35_RS03155 (G8B35_03165) | - | 625731..626486 (-) | 756 | WP_010922480.1 | XRE family transcriptional regulator | - |
| G8B35_RS03160 (G8B35_03170) | - | 626688..626900 (+) | 213 | WP_010922479.1 | helix-turn-helix domain-containing protein | - |
| G8B35_RS03165 (G8B35_03175) | - | 627170..627481 (+) | 312 | WP_010922478.1 | excisionase | - |
| G8B35_RS03170 (G8B35_03180) | - | 627483..627668 (+) | 186 | WP_010922477.1 | hypothetical protein | - |
| G8B35_RS09500 | - | 627762..628031 (+) | 270 | WP_011106700.1 | replication protein | - |
| G8B35_RS03175 (G8B35_03185) | - | 628157..628543 (+) | 387 | WP_011017564.1 | DnaD domain-containing protein | - |
| G8B35_RS03180 (G8B35_03190) | - | 628524..628758 (+) | 235 | Protein_566 | hypothetical protein | - |
| G8B35_RS03185 (G8B35_03195) | - | 628755..628895 (+) | 141 | WP_002988354.1 | hypothetical protein | - |
| G8B35_RS03190 (G8B35_03200) | - | 628904..629110 (+) | 207 | WP_002988357.1 | hypothetical protein | - |
| G8B35_RS03195 (G8B35_03205) | - | 629166..629495 (+) | 330 | WP_011528796.1 | hypothetical protein | - |
| G8B35_RS03200 (G8B35_03210) | - | 629498..630419 (+) | 922 | Protein_570 | recombinase RecT | - |
| G8B35_RS03205 (G8B35_03215) | - | 630416..630616 (+) | 201 | WP_000594115.1 | hypothetical protein | - |
| G8B35_RS03210 (G8B35_03220) | - | 630609..631406 (+) | 798 | WP_011054699.1 | PD-(D/E)XK nuclease-like domain-containing protein | - |
| G8B35_RS03215 (G8B35_03225) | - | 631771..632166 (+) | 396 | WP_011054698.1 | Cas9 inhibitor AcrIIA9 family protein | - |
| G8B35_RS03220 (G8B35_03230) | - | 632163..633509 (+) | 1347 | WP_011054697.1 | PcfJ domain-containing protein | - |
| G8B35_RS03225 (G8B35_03235) | - | 633520..633852 (+) | 333 | WP_011184741.1 | hypothetical protein | - |
| G8B35_RS03230 (G8B35_03240) | - | 633849..634361 (+) | 513 | WP_011054695.1 | hypothetical protein | - |
| G8B35_RS03235 (G8B35_03245) | - | 634397..634714 (+) | 318 | WP_011054694.1 | DUF1372 family protein | - |
| G8B35_RS03240 (G8B35_03250) | - | 634711..634866 (+) | 156 | WP_011054693.1 | hypothetical protein | - |
| G8B35_RS03245 (G8B35_03255) | - | 634863..635114 (+) | 252 | WP_011054692.1 | hypothetical protein | - |
| G8B35_RS03250 (G8B35_03260) | - | 635190..635609 (+) | 420 | WP_011528791.1 | DUF1492 domain-containing protein | - |
| G8B35_RS03255 (G8B35_03265) | - | 635717..636061 (+) | 345 | WP_011054690.1 | HNH endonuclease signature motif containing protein | - |
| G8B35_RS03260 (G8B35_03270) | - | 636209..636565 (+) | 357 | WP_002994106.1 | hypothetical protein | - |
| G8B35_RS03265 (G8B35_03275) | - | 636562..637830 (+) | 1269 | WP_219271343.1 | phage portal protein | - |
| G8B35_RS03270 (G8B35_03280) | - | 637823..639316 (+) | 1494 | WP_010922467.1 | hypothetical protein | - |
| G8B35_RS03275 (G8B35_03285) | - | 639322..639546 (+) | 225 | WP_002994100.1 | hypothetical protein | - |
| G8B35_RS03280 (G8B35_03290) | - | 639598..639864 (+) | 267 | WP_011054745.1 | hypothetical protein | - |
| G8B35_RS03285 (G8B35_03295) | - | 639866..640102 (+) | 237 | Protein_587 | hypothetical protein | - |
| G8B35_RS03290 (G8B35_03300) | - | 640184..641599 (+) | 1416 | WP_021299324.1 | phage terminase large subunit-like protein | - |
| G8B35_RS03295 (G8B35_03305) | - | 641679..642140 (+) | 462 | WP_010922462.1 | DUF4355 domain-containing protein | - |
| G8B35_RS03300 (G8B35_03310) | - | 642165..643076 (+) | 912 | WP_011528788.1 | phage major capsid protein | - |
| G8B35_RS03305 (G8B35_03315) | - | 643076..643276 (+) | 201 | WP_010922460.1 | hypothetical protein | - |
| G8B35_RS03310 (G8B35_03320) | - | 643286..643708 (+) | 423 | WP_011054682.1 | phage Gp19/Gp15/Gp42 family protein | - |
| G8B35_RS03315 (G8B35_03325) | - | 643668..644006 (+) | 339 | WP_011054681.1 | hypothetical protein | - |
| G8B35_RS03320 (G8B35_03330) | - | 643999..644235 (+) | 237 | WP_000032787.1 | hypothetical protein | - |
| G8B35_RS03325 (G8B35_03335) | - | 644236..644571 (+) | 336 | WP_011528787.1 | hypothetical protein | - |
| G8B35_RS03330 (G8B35_03340) | - | 644583..645161 (+) | 579 | WP_014635577.1 | hypothetical protein | - |
| G8B35_RS03335 (G8B35_03345) | - | 645172..645435 (+) | 264 | WP_003047548.1 | hypothetical protein | - |
| G8B35_RS03340 (G8B35_03350) | - | 645450..645821 (+) | 372 | WP_011528785.1 | DUF5361 domain-containing protein | - |
| G8B35_RS03345 (G8B35_03355) | - | 645821..648178 (+) | 2358 | WP_011528784.1 | hypothetical protein | - |
| G8B35_RS03350 (G8B35_03360) | - | 648175..648870 (+) | 696 | WP_002992579.1 | hypothetical protein | - |
| G8B35_RS03355 (G8B35_03365) | - | 648852..650828 (+) | 1977 | WP_011528783.1 | phage tail spike protein | - |
| G8B35_RS03360 (G8B35_03370) | hylP | 650825..651940 (+) | 1116 | WP_011528782.1 | hyaluronoglucosaminidase | - |
| G8B35_RS03365 (G8B35_03375) | - | 651955..653736 (+) | 1782 | WP_219271345.1 | gp58-like family protein | - |
| G8B35_RS03370 (G8B35_03380) | - | 653745..654173 (+) | 429 | WP_011528780.1 | DUF1617 family protein | - |
| G8B35_RS03375 (G8B35_03385) | - | 654176..654808 (+) | 633 | WP_011528779.1 | hypothetical protein | - |
| G8B35_RS03380 (G8B35_03390) | - | 654820..655092 (+) | 273 | WP_011017397.1 | hypothetical protein | - |
| G8B35_RS03385 (G8B35_03395) | - | 655089..655316 (+) | 228 | WP_003058873.1 | phage holin | - |
| G8B35_RS03390 (G8B35_03400) | - | 655435..656652 (+) | 1218 | WP_011528778.1 | peptidoglycan amidohydrolase family protein | - |
| G8B35_RS03395 (G8B35_03405) | - | 656788..657912 (+) | 1125 | WP_002988467.1 | Fic family protein | - |
| G8B35_RS03400 (G8B35_03410) | entC3 | 658160..658942 (+) | 783 | WP_002988472.1 | enterotoxin type C3 EntC3 | - |
| G8B35_RS03405 (G8B35_03415) | prx | 659055..659237 (+) | 183 | WP_011528776.1 | hypothetical protein | Regulator |
Sequence
Protein
Download Length: 60 a.a. Molecular weight: 6840.81 Da Isoelectric Point: 4.7023
>NTDB_id=427256 G8B35_RS03405 WP_011528776.1 659055..659237(+) (prx) [Streptococcus pyogenes strain ABC3]
MLTYNEFKQAIDNGYIAGDTVAIVRKDGQIFDYVLPHEKVKNGEVVTKEKVEEVLVELSR
MLTYNEFKQAIDNGYIAGDTVAIVRKDGQIFDYVLPHEKVKNGEVVTKEKVEEVLVELSR
Nucleotide
Download Length: 183 bp
>NTDB_id=427256 G8B35_RS03405 WP_011528776.1 659055..659237(+) (prx) [Streptococcus pyogenes strain ABC3]
ATGCTAACATACAACGAGTTTAAGCAAGCGATTGACAATGGATATATCGCAGGCGATACAGTAGCGATCGTGCGTAAAGA
CGGACAGATTTTTGATTATGTGTTGCCACATGAGAAAGTAAAGAATGGAGAAGTTGTGACTAAGGAAAAAGTGGAAGAGG
TGCTGGTGGAGCTTTCGAGATAA
ATGCTAACATACAACGAGTTTAAGCAAGCGATTGACAATGGATATATCGCAGGCGATACAGTAGCGATCGTGCGTAAAGA
CGGACAGATTTTTGATTATGTGTTGCCACATGAGAAAGTAAAGAATGGAGAAGTTGTGACTAAGGAAAAAGTGGAAGAGG
TGCTGGTGGAGCTTTCGAGATAA
Domains
No domain identified.
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| prx | Streptococcus pyogenes MGAS8232 |
98.333 |
100 |
0.983 |
| prx | Streptococcus pyogenes MGAS315 |
83.333 |
100 |
0.833 |
| prx | Streptococcus pyogenes MGAS315 |
78.333 |
100 |
0.783 |
| prx | Streptococcus pyogenes MGAS315 |
71.667 |
100 |
0.717 |
| prx | Streptococcus pyogenes MGAS315 |
87.805 |
68.333 |
0.6 |
| prx | Streptococcus pyogenes MGAS315 |
81.395 |
71.667 |
0.583 |
| prx | Streptococcus pyogenes MGAS315 |
76.19 |
70 |
0.533 |