Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   ST64987_RS09930 Genome accession   NZ_CP049053
Coordinates   262870..263160 (+) Length   96 a.a.
NCBI ID   WP_194238295.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ST64987     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 257870..268160
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST64987_RS01455 (ST64987_0254) - 258912..259451 (+) 540 WP_372585740.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  ST64987_RS01460 (ST64987_0255) - 259762..260319 (+) 558 WP_011680718.1 ECF transporter S component -
  ST64987_RS01465 (ST64987_0256) - 260322..260972 (+) 651 WP_011680719.1 phosphatase PAP2 family protein -
  ST64987_RS01470 (ST64987_0257) comR 261167..262066 (+) 900 WP_011680720.1 helix-turn-helix domain-containing protein Regulator
  ST64987_RS09925 - 262304..262885 (+) 582 Protein_230 cysteine peptidase family C39 domain-containing protein -
  ST64987_RS09930 comA 262870..263160 (+) 291 WP_194238295.1 ABC transporter transmembrane domain-containing protein Regulator
  ST64987_RS10035 comA 263503..263712 (+) 210 WP_002946147.1 hypothetical protein Regulator
  ST64987_RS10040 (ST64987_0260) - 263767..264335 (+) 569 Protein_233 ATP-binding cassette domain-containing protein -
  ST64987_RS10045 (ST64987_0261) - 264566..264754 (+) 189 WP_224103239.1 hypothetical protein -
  ST64987_RS10050 - 264722..265006 (-) 285 WP_232557103.1 hypothetical protein -
  ST64987_RS10055 - 265247..265549 (-) 303 WP_224103194.1 hypothetical protein -
  ST64987_RS10060 (ST64987_0262) - 265773..266144 (-) 372 WP_224103195.1 hypothetical protein -
  ST64987_RS01510 (ST64987_0263) - 266549..267064 (+) 516 WP_002949547.1 AmiS/UreI family transporter -
  ST64987_RS01515 (ST64987_0264) - 267089..267391 (+) 303 WP_002886558.1 urease subunit gamma -
  ST64987_RS01520 (ST64987_0265) - 267403..267714 (+) 312 WP_002886559.1 urease subunit beta -

Sequence

Protein


Download         Length: 96 a.a.        Molecular weight: 10752.77 Da        Isoelectric Point: 7.1599

>NTDB_id=424507 ST64987_RS09930 WP_194238295.1 262870..263160(+) (comA) [Streptococcus thermophilus strain ST64987]
MLAYLAQQVFTFFKDYLLHRLGNYFSISVILPYIKHVLSLPISFFGSRRTGEITSCFGDANTIIDALASTILSIFLDVTI
VITLAVALILQTVLFF

Nucleotide


Download         Length: 291 bp        

>NTDB_id=424507 ST64987_RS09930 WP_194238295.1 262870..263160(+) (comA) [Streptococcus thermophilus strain ST64987]
GTGCTCGCCTATCTAGCCCAACAAGTCTTCACTTTTTTCAAAGATTATCTTCTACATCGATTGGGTAATTACTTCTCCAT
TTCTGTTATCCTTCCTTATATCAAGCATGTCCTTTCTTTGCCCATTAGTTTCTTCGGTTCACGTCGTACTGGTGAAATCA
CGTCATGTTTTGGAGATGCCAACACTATTATCGATGCTCTAGCTTCAACAATCTTATCGATTTTCCTAGATGTCACCATT
GTGATAACTTTAGCTGTCGCCCTTATTTTACAAACCGTTCTCTTTTTTTGA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(2-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus gordonii str. Challis substr. CH1

59.794

100

0.604
  comA Streptococcus pneumoniae D39

58.763

100

0.594
  comA Streptococcus pneumoniae R6

58.763

100

0.594
  comA Streptococcus mitis SK321

58.763

100

0.594
  comA Streptococcus mitis NCTC 12261

58.763

100

0.594
  comA Streptococcus pneumoniae TIGR4

58.763

100

0.594
  comA Streptococcus pneumoniae Rx1

58.763

100

0.594
  comA/nlmT Streptococcus mutans UA159

57.732

100

0.583