Detailed information NTG0422354

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: G3T58_RS25030
• Genome accession: NZ_CP048687
• Coordinates: 4943244..4943825 (+)
• Length: 193 a.a.
• NCBI ID: WP_000991609.1
• Uniprot ID: A0A853X8N5
• Organism: Bacillus paranthracis strain MN1F
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 4938244..4948825

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
G3T58_RS25005	-	4939364..4940731 (+)	1368	WP_046952019.1	lytic polysaccharide monooxygenase	-
G3T58_RS25010	-	4940862..4941296 (-)	435	WP_000555714.1	GNAT family N-acetyltransferase	-
G3T58_RS25015	rpiA	4941405..4942067 (-)	663	WP_001049998.1	ribose 5-phosphate isomerase A	-
G3T58_RS25020	-	4942072..4942392 (-)	321	WP_001125382.1	2Fe-2S iron-sulfur cluster-binding protein	-
G3T58_RS25025	-	4942536..4943222 (+)	687	WP_000337489.1	RNA polymerase subunit sigma-70	-
G3T58_RS25030	clpP	4943244..4943825 (+)	582	WP_000991609.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
G3T58_RS25035	-	4943871..4944728 (-)	858	WP_001227645.1	glycine betaine ABC transporter substrate-binding protein	-
G3T58_RS25040	-	4944899..4946104 (+)	1206	WP_000370623.1	glycine betaine/L-proline ABC transporter ATP-binding protein	-
G3T58_RS25045	-	4946097..4946933 (+)	837	WP_001084753.1	proline/glycine betaine ABC transporter permease	-
G3T58_RS25050	-	4947230..4947400 (+)	171	WP_001992228.1	hypothetical protein	-
G3T58_RS25055	-	4947503..4947988 (+)	486	WP_002080579.1	HIT family protein	-
G3T58_RS25060	-	4947972..4948808 (+)	837	WP_052760724.1	PP2C family serine/threonine-protein phosphatase	-

Sequence

Protein

• Length: 193 a.a.
• Molecular weight: 21192.49 Da
• Isoelectric Point: 5.3394

>NTDB_id=422354 G3T58_RS25030 WP_000991609.1 4943244..4943825(+) (clpP) [Bacillus paranthracis strain MN1F]
MNAIPYVVEQTKLGERSYDIYSRLLKDRIIIIGSEINDQVASSVVAQLLFLEAEDAEKDIFLYINSPGGSTTAGFAILDT
MNLIKPDVQTLCMGFAASFGALLLLSGAKGKRFALPNSEIMIHQPLGGAKGQATEIEITAKRILKLKHDINKMIAEKTGQ
PIERVAHDTERDYFMTAEEAKAYGIVDDVVTKK

Nucleotide

• Length: 582 bp

>NTDB_id=422354 G3T58_RS25030 WP_000991609.1 4943244..4943825(+) (clpP) [Bacillus paranthracis strain MN1F]
ATGAATGCAATTCCATATGTTGTAGAACAAACGAAATTAGGAGAACGTTCCTATGATATATATTCAAGGTTATTGAAAGA
CCGTATTATTATTATCGGTTCAGAAATAAATGATCAAGTAGCGAGTAGTGTCGTAGCTCAATTATTATTTTTAGAAGCAG
AAGATGCAGAGAAAGATATATTTTTATACATTAATAGCCCAGGCGGATCAACGACAGCGGGATTTGCTATATTAGATACA
ATGAATTTAATCAAACCTGATGTACAAACGCTATGCATGGGCTTTGCAGCATCATTTGGTGCATTGTTATTATTATCAGG
TGCAAAAGGAAAACGATTTGCACTCCCGAATAGTGAAATTATGATTCATCAGCCACTTGGTGGTGCAAAAGGGCAGGCAA
CAGAAATTGAAATAACAGCAAAAAGAATTTTAAAGTTAAAACATGATATTAATAAAATGATTGCAGAAAAAACAGGGCAA
CCGATTGAAAGAGTAGCACATGATACAGAAAGAGATTATTTTATGACTGCAGAAGAAGCGAAGGCATATGGGATTGTAGA
TGATGTTGTTACGAAAAAATAG

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (14-192)

3D structure

• AlphaFold DB: A0A853X8N5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	68.063	98.964	0.674
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	67.196	97.927	0.658
clpP	Streptococcus pyogenes JRS4	56.085	97.927	0.549
clpP	Streptococcus pyogenes MGAS315	56.085	97.927	0.549
clpP	Streptococcus pneumoniae R6	55.208	99.482	0.549
clpP	Streptococcus pneumoniae TIGR4	55.208	99.482	0.549
clpP	Streptococcus pneumoniae Rx1	55.208	99.482	0.549
clpP	Streptococcus thermophilus LMG 18311	55.208	99.482	0.549
clpP	Streptococcus thermophilus LMD-9	55.208	99.482	0.549
clpP	Streptococcus pneumoniae D39	55.208	99.482	0.549
clpP	Streptococcus mutans UA159	53.968	97.927	0.528
clpP	Lactococcus lactis subsp. cremoris KW2	51.852	97.927	0.508
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	50.265	97.927	0.492