Detailed information NTG0419968

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: M662_RS14320
• Genome accession: NZ_CP048117
• Coordinates: 2718205..2718795 (+)
• Length: 196 a.a.
• NCBI ID: WP_008634093.1
• Uniprot ID: A0A7Z2SYB9
• Organism: Bacillus sp. SB49
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2713205..2723795

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M662_RS14290 (M662_14265)	-	2713511..2714692 (-)	1182	WP_026578236.1	phosphoglycerate kinase	-
M662_RS14295 (M662_14270)	gap	2714865..2715872 (-)	1008	WP_008634098.1	type I glyceraldehyde-3-phosphate dehydrogenase	-
M662_RS14300 (M662_14275)	-	2715909..2716937 (-)	1029	WP_026578235.1	sugar-binding transcriptional regulator	-
M662_RS14305 (M662_14280)	-	2717090..2717311 (-)	222	WP_008634095.1	glutaredoxin family protein	-
M662_RS14310 (M662_14285)	-	2717345..2717569 (-)	225	WP_008634094.1	hypothetical protein	-
M662_RS14320 (M662_14295)	clpP	2718205..2718795 (+)	591	WP_008634093.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
M662_RS14325 (M662_14300)	-	2718891..2719142 (-)	252	WP_008634092.1	HPr family phosphocarrier protein	-
M662_RS14330 (M662_14305)	whiA	2719273..2720229 (-)	957	WP_008634091.1	DNA-binding protein WhiA	-
M662_RS14335 (M662_14310)	-	2720262..2721215 (-)	954	WP_008634090.1	YvcK family protein	-
M662_RS14340 (M662_14315)	rapZ	2721219..2722103 (-)	885	WP_026578234.1	RNase adapter RapZ	-
M662_RS14345 (M662_14320)	-	2722119..2722589 (-)	471	WP_026578233.1	8-oxo-dGTP diphosphatase	-
M662_RS14350 (M662_14325)	trxB	2722821..2723771 (-)	951	WP_008634082.1	thioredoxin-disulfide reductase	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21645.80 Da
• Isoelectric Point: 4.7578

>NTDB_id=419968 M662_RS14320 WP_008634093.1 2718205..2718795(+) (clpP) [Bacillus sp. SB49]
MNLVPTVIEQTNRGERAYDIYSRLLKDRIIMLGSPIDDNIANSVVSQLLFLAADDPEKDISLYINSPGGSITAGMAIYDT
MQFIKPDVSTICTGMAASMGAFLLNAGEPGKRYALPNSEVMIHQPLGGTQGQATDIEIHAKRIIKMREKLNQILSERTGQ
PIEVIERDTDRDNFMSAHEAVEYGLIDKVMTKVTDK

Nucleotide

• Length: 591 bp

>NTDB_id=419968 M662_RS14320 WP_008634093.1 2718205..2718795(+) (clpP) [Bacillus sp. SB49]
ATGAATCTAGTCCCAACAGTTATTGAACAGACAAACCGTGGAGAGCGTGCTTACGACATTTACTCCCGCTTACTTAAAGA
CCGTATCATCATGCTCGGCAGCCCGATCGATGATAATATCGCGAACTCTGTCGTTTCCCAGCTGCTATTCCTTGCAGCTG
ATGATCCGGAGAAAGATATCTCTCTATACATTAACTCTCCGGGTGGATCTATTACCGCAGGTATGGCCATCTATGATACG
ATGCAGTTCATCAAGCCTGATGTATCCACCATCTGTACAGGTATGGCAGCGTCTATGGGTGCGTTCCTCCTTAATGCAGG
AGAACCCGGCAAACGTTACGCACTTCCTAACAGTGAAGTAATGATCCACCAGCCGCTTGGAGGTACGCAAGGACAAGCGA
CGGACATCGAGATTCACGCGAAACGAATTATTAAAATGCGTGAAAAATTAAACCAAATCCTTTCCGAGCGTACAGGTCAG
CCGATTGAAGTAATCGAGCGCGACACAGACCGCGACAACTTTATGTCCGCACATGAAGCGGTAGAGTATGGTTTGATTGA
TAAGGTTATGACAAAAGTTACAGACAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: A0A7Z2SYB9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	85.204	100	0.852
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	66.842	96.939	0.648
clpP	Streptococcus thermophilus LMG 18311	60.209	97.449	0.587
clpP	Streptococcus thermophilus LMD-9	60.209	97.449	0.587
clpP	Streptococcus pneumoniae TIGR4	58.947	96.939	0.571
clpP	Streptococcus pneumoniae D39	58.947	96.939	0.571
clpP	Lactococcus lactis subsp. cremoris KW2	58.947	96.939	0.571
clpP	Streptococcus pneumoniae Rx1	58.947	96.939	0.571
clpP	Streptococcus pneumoniae R6	58.947	96.939	0.571
clpP	Streptococcus pyogenes JRS4	57.368	96.939	0.556
clpP	Streptococcus pyogenes MGAS315	57.368	96.939	0.556
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	57.368	96.939	0.556
clpP	Streptococcus mutans UA159	56.545	97.449	0.551