Detailed information NTG0418265

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: M594_RS07165
• Genome accession: NZ_CP047883
• Coordinates: 1463797..1464387 (-)
• Length: 196 a.a.
• NCBI ID: WP_000613471.1
• Uniprot ID: A0A1E9GI28
• Organism: Streptococcus mitis strain S022-V3-A4
• Function: degradation of ComX; degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 1458797..1469387

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M594_RS07140 (M594_07165)	-	1459394..1460158 (-)	765	WP_001185997.1	ABC transporter ATP-binding protein	-
M594_RS07145 (M594_07170)	-	1460158..1461114 (-)	957	WP_000662286.1	branched-chain amino acid ABC transporter permease	-
M594_RS07150 (M594_07175)	-	1461118..1461987 (-)	870	WP_000941421.1	branched-chain amino acid ABC transporter permease	-
M594_RS07155 (M594_07180)	-	1462209..1463369 (-)	1161	WP_173876364.1	ABC transporter substrate-binding protein	-
M594_RS07160 (M594_07185)	-	1463431..1463718 (-)	288	WP_173876365.1	YlbG family protein	-
M594_RS07165 (M594_07190)	clpP	1463797..1464387 (-)	591	WP_000613471.1	ATP-dependent Clp protease proteolytic subunit ClpP	Regulator
M594_RS07170 (M594_07195)	upp	1464561..1465190 (-)	630	WP_000515974.1	uracil phosphoribosyltransferase	-
M594_RS07175 (M594_07200)	-	1465280..1465747 (-)	468	WP_023947240.1	deoxycytidylate deaminase	-
M594_RS07180 (M594_07205)	-	1465766..1466323 (-)	558	WP_000004136.1	TetR/AcrR family transcriptional regulator	-
M594_RS07185 (M594_07210)	-	1466448..1467293 (+)	846	WP_173876366.1	DegV family protein	-
M594_RS07190 (M594_07215)	-	1467352..1468524 (+)	1173	WP_173876367.1	NAD(P)/FAD-dependent oxidoreductase	-
M594_RS07195 (M594_07220)	-	1468573..1469094 (+)	522	WP_173876368.1	DUF1697 domain-containing protein	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21352.38 Da
• Isoelectric Point: 4.4910

>NTDB_id=418265 M594_RS07165 WP_000613471.1 1463797..1464387(-) (clpP) [Streptococcus mitis strain S022-V3-A4]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNILEKILAENSGQ
SIEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN

Nucleotide

• Length: 591 bp

>NTDB_id=418265 M594_RS07165 WP_000613471.1 1463797..1464387(-) (clpP) [Streptococcus mitis strain S022-V3-A4]
ATGATTCCTGTAGTTATTGAACAAACAAGTCGTGGAGAACGTTCCTACGATATTTACTCACGTCTTCTCAAAGACCGCAT
CATCATGCTGACAGGTCCAGTTGAAGACAATATGGCTAACTCTGTTATTGCCCAATTGCTTTTCTTGGATGCCCAAGACA
GTACAAAAGATATTTACCTTTATGTCAATACACCTGGTGGTTCAGTTTCAGCTGGTTTGGCAATCGTTGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACTATCGTTATGGGGATGGCTGCATCTATGGGGACGGTCATTGCATCAAGTGGAGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCAGAGTATATGATCCACCAACCAATGGGTGGTACAGGTGGTGGTACTCAACAAA
CCGATATGGCGATTGCTGCAGAACACTTGCTCAAAACTCGTAACATCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAG
TCAATCGAAAAAGTCCATGCAGATGCAGAACGCGATAATTGGATGAGCGCCCAAGAAACACTTGAATATGGCTTTATTGA
TGAAATCATGGCCAACAATTCATTGAACTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A1E9GI28

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pneumoniae Rx1	98.98	100	0.99
clpP	Streptococcus pneumoniae D39	98.98	100	0.99
clpP	Streptococcus pneumoniae R6	98.98	100	0.99
clpP	Streptococcus pneumoniae TIGR4	98.98	100	0.99
clpP	Streptococcus thermophilus LMG 18311	93.333	99.49	0.929
clpP	Streptococcus thermophilus LMD-9	93.333	99.49	0.929
clpP	Streptococcus pyogenes JRS4	91.282	99.49	0.908
clpP	Streptococcus pyogenes MGAS315	91.282	99.49	0.908
clpP	Streptococcus mutans UA159	86.224	100	0.862
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	85.128	99.49	0.847
clpP	Lactococcus lactis subsp. cremoris KW2	84.615	99.49	0.842
clpP	Bacillus subtilis subsp. subtilis str. 168	58.854	97.959	0.577
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.549	98.469	0.577