Detailed information NTG0041801

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: SALIVB_RS01455
• Genome accession: NC_015760
• Coordinates: 269373..271469 (+)
• Length: 698 a.a.
• NCBI ID: WP_013990040.1
• Uniprot ID: -
• Organism: Streptococcus salivarius CCHSS3
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 264373..276469

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SALIVB_RS01430 (SALIVB_0284)	trkA	264465..265814 (-)	1350	WP_013990035.1	Trk system potassium transporter TrkA	-
SALIVB_RS01435 (SALIVB_0285)	-	266092..266601 (+)	510	WP_013990036.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
SALIVB_RS01440 (SALIVB_0286)	-	266910..267467 (+)	558	WP_013990037.1	ECF transporter S component	-
SALIVB_RS01445 (SALIVB_0287)	-	267470..268120 (+)	651	WP_013990038.1	phosphatase PAP2 family protein	-
SALIVB_RS01450 (SALIVB_0288)	comR	268299..269198 (+)	900	WP_013990039.1	helix-turn-helix transcriptional regulator	Regulator
SALIVB_RS01455 (SALIVB_0289)	comA	269373..271469 (+)	2097	WP_013990040.1	peptide cleavage/export ABC transporter	Regulator
SALIVB_RS01460 (SALIVB_0290)	-	271579..271911 (+)	333	WP_013990041.1	DUF805 domain-containing protein	-
SALIVB_RS11160 (SALIVB_0291)	-	271963..272382 (-)	420	WP_231844793.1	hypothetical protein	-
SALIVB_RS01470 (SALIVB_0292)	-	272770..273285 (+)	516	WP_002886548.1	AmiS/UreI family transporter	-
SALIVB_RS01475 (SALIVB_0293)	-	273310..273612 (+)	303	WP_002886558.1	urease subunit gamma	-
SALIVB_RS01480 (SALIVB_0294)	-	273624..273935 (+)	312	WP_002886559.1	urease subunit beta	-
SALIVB_RS01485 (SALIVB_0295)	ureC	273951..275669 (+)	1719	WP_002886560.1	urease subunit alpha	-
SALIVB_RS01490 (SALIVB_0296)	ureE	275810..276262 (+)	453	WP_002886561.1	urease accessory protein UreE	-

Sequence

Protein

• Length: 698 a.a.
• Molecular weight: 78569.48 Da
• Isoelectric Point: 8.8163

>NTDB_id=41801 SALIVB_RS01455 WP_013990040.1 269373..271469(+) (comA) [Streptococcus salivarius CCHSS3]
MSKYPYISQIDQRDCGVAALAMILKHYGSSYSLAYLRELAQTSREGTSALGLVEAAKQLGLETQAIRADLDLFKQENLSY
PFIAHVVKEGGLQHYYTVFGQIKGKLVIGDPDPSKKVIKMPLEEFAKEWTGVALFFVPGETYTKYKEDVPELLSFLPILF
RRKGLIAVIVLLSFLVTLVNIIGSYYLQSIIDRLIPQEAYTLLTMISLGLCISYLAQQVFTFFKDYLLHRLGNYLSIAVI
LPYIKHVLSLPISFFSSRRTGEITSRFGDANTIIDALASTILSIFLDVTIVMTLAVALILQNQSLFVMTLTVVPLYVLII
LAFYKLFEKENYQLMEANSQVNTAVIDDLRGIETLKSLRVEERRYQEIEVKFHDYLKKSLSKAKWQLTQDGLKTGVQLVS
NVFILWYGAQLVMEGQLSAGQLITYNMLLNYFTTPLINIINLQSKIQQAKVANNRLQEVYVVDKEEEGKLKELSFKQLAL
KGVSHRFSYQQETLSKIDLTIHKGEKIALMGKSGSGKTTLAKMLSGYYTKSSGHVTLDKDAISHAELRQMVTYVPQQTYV
FTGTILENLLLGYEGEVDEKKLLKVCQQADILEDIQKMPLGFQTQVSEDGGLSGGQKQRLAIARALLSKQPILVFDEATS
GLDSDTESRVMANLAKIKRTMIFIAHRNSVRQHVSRVVTMVSGQIESDSPNFNPFQFI

Nucleotide

• Length: 2097 bp

>NTDB_id=41801 SALIVB_RS01455 WP_013990040.1 269373..271469(+) (comA) [Streptococcus salivarius CCHSS3]
ATGTCAAAATATCCATATATTTCACAGATTGATCAGCGTGATTGTGGTGTCGCTGCCTTAGCCATGATTCTTAAACACTA
TGGTTCATCTTATAGTTTAGCTTATTTGCGGGAGTTGGCTCAGACTTCTCGTGAAGGCACTTCTGCGCTTGGTTTGGTTG
AAGCGGCCAAGCAGTTGGGTCTTGAAACTCAGGCTATTCGTGCGGATTTAGACTTGTTTAAACAAGAAAACCTATCTTAT
CCTTTTATTGCACATGTGGTTAAAGAAGGTGGATTGCAACATTATTATACGGTGTTTGGTCAAATCAAGGGGAAGCTTGT
TATTGGTGATCCAGATCCTAGCAAGAAGGTCATTAAAATGCCCTTAGAGGAGTTTGCCAAAGAGTGGACAGGAGTTGCTC
TCTTTTTTGTTCCAGGAGAAACCTACACTAAATACAAAGAAGATGTGCCTGAGCTTCTTTCATTTTTACCGATTTTGTTC
CGTCGTAAGGGTTTGATTGCAGTTATTGTCTTGTTAAGTTTTCTAGTGACCCTAGTTAATATCATTGGTTCTTATTATTT
GCAATCTATTATTGACCGCTTGATTCCTCAGGAGGCCTACACTCTTCTAACCATGATTTCACTGGGTCTATGTATCTCTT
ATCTAGCTCAACAAGTATTTACTTTTTTCAAAGATTATCTTCTACATCGATTGGGAAATTACTTATCCATTGCTGTCATT
CTTCCTTATATTAAGCATGTCCTTTCCTTGCCTATTAGTTTCTTTAGTTCACGTCGCACTGGTGAAATCACGTCACGTTT
TGGAGATGCCAACACTATTATCGATGCTCTAGCTTCAACGATTTTATCGATTTTCCTAGATGTGACCATTGTGATGACTT
TAGCTGTGGCCCTTATTTTACAAAATCAGTCACTTTTTGTGATGACTCTCACGGTAGTTCCTCTTTATGTGTTAATCATT
TTGGCCTTCTATAAGCTTTTTGAAAAGGAAAATTATCAATTGATGGAGGCAAATAGTCAGGTCAATACCGCTGTTATTGA
TGATTTGCGAGGCATTGAAACCTTAAAATCCTTGAGAGTTGAAGAAAGACGCTATCAGGAAATTGAGGTGAAATTCCATG
ACTATTTGAAGAAGTCTTTGTCTAAGGCCAAGTGGCAATTAACGCAGGATGGTTTAAAGACAGGGGTTCAGTTAGTTTCC
AATGTCTTTATCCTCTGGTATGGGGCACAATTGGTCATGGAAGGGCAACTATCTGCAGGTCAGTTGATTACTTATAATAT
GTTGCTGAATTATTTTACAACTCCTTTAATTAATATTATCAATCTCCAATCCAAAATTCAGCAAGCCAAAGTAGCCAATA
ATCGTCTTCAAGAAGTTTATGTTGTGGATAAGGAAGAAGAAGGAAAACTTAAAGAGTTATCTTTTAAACAACTTGCTCTT
AAAGGAGTCAGTCACCGTTTTAGTTATCAGCAAGAGACGCTTAGTAAGATTGATTTAACGATTCATAAGGGTGAGAAAAT
CGCCCTCATGGGTAAAAGTGGATCTGGGAAAACAACCTTAGCGAAAATGTTGTCAGGTTATTACACAAAATCTAGTGGTC
ATGTAACCCTAGATAAAGATGCTATTAGCCATGCGGAGCTGCGTCAAATGGTGACTTACGTTCCCCAGCAGACCTATGTG
TTTACAGGAACCATTTTAGAAAATCTGCTATTAGGATATGAAGGAGAAGTTGATGAGAAAAAGCTTCTTAAAGTTTGCCA
ACAAGCTGATATCTTAGAGGATATTCAAAAAATGCCACTAGGTTTTCAGACCCAAGTATCTGAAGACGGTGGTCTATCTG
GTGGTCAAAAACAACGCTTGGCGATAGCGAGGGCCCTCTTGTCCAAGCAGCCTATCTTGGTTTTTGACGAAGCTACCAGT
GGTCTTGATAGTGATACTGAAAGCAGGGTCATGGCTAATCTTGCTAAGATTAAACGAACAATGATTTTTATTGCTCACCG
CAATAGTGTCCGTCAACATGTCAGTCGTGTGGTGACCATGGTGAGTGGCCAGATTGAGTCAGACAGTCCTAATTTCAATC
CATTCCAGTTTATTTAA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (3-139)

• ABC transporter transmembrane region (ABC_membrane) (167-436)

• ABC transporter (ABC_tran) (494-640)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis SK321	53.546	98.997	0.53
comA	Streptococcus gordonii str. Challis substr. CH1	53.161	99.713	0.53
comA	Streptococcus mitis NCTC 12261	53.111	98.997	0.526
comA	Streptococcus pneumoniae Rx1	52.967	98.997	0.524
comA	Streptococcus pneumoniae D39	52.967	98.997	0.524
comA	Streptococcus pneumoniae R6	52.967	98.997	0.524
comA	Streptococcus pneumoniae TIGR4	52.822	98.997	0.523
comA/nlmT	Streptococcus mutans UA159	50.145	98.854	0.496