Detailed information NTG0414658

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: GU336_RS10140
• Genome accession: NZ_CP047616
• Coordinates: 2070871..2071467 (-)
• Length: 198 a.a.
• NCBI ID: WP_061775221.1
• Uniprot ID: A0A290PWM7
• Organism: Lactococcus raffinolactis strain Lr_19_5
• Function: degradation of ComX; degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 2065871..2076467

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GU336_RS10105 (GU336_10100)	-	2066291..2067109 (-)	819	WP_061774147.1	NAD kinase	-
GU336_RS10110 (GU336_10105)	-	2067090..2067788 (-)	699	WP_281063660.1	GTP pyrophosphokinase family protein	-
GU336_RS10115 (GU336_10110)	-	2068280..2068489 (+)	210	WP_239519127.1	DUF4177 domain-containing protein	-
GU336_RS10120 (GU336_10115)	-	2068686..2069276 (+)	591	WP_096039490.1	CYTH domain-containing protein	-
GU336_RS10125 (GU336_10120)	-	2069567..2070094 (+)	528	WP_157738480.1	DsbA family protein	-
GU336_RS10130 (GU336_10125)	-	2070091..2070429 (-)	339	WP_061774139.1	YlbG family protein	-
GU336_RS10135 (GU336_10130)	-	2070410..2070787 (-)	378	WP_096039492.1	hypothetical protein	-
GU336_RS10140 (GU336_10135)	clpP	2070871..2071467 (-)	597	WP_061775221.1	ATP-dependent Clp protease proteolytic subunit	Regulator
GU336_RS10145 (GU336_10140)	-	2071667..2073094 (-)	1428	WP_301952876.1	NADP-dependent glyceraldehyde-3-phosphate dehydrogenase	-
GU336_RS10150 (GU336_10145)	-	2073812..2074810 (-)	999	WP_061775219.1	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	-
GU336_RS10155 (GU336_10150)	cysK	2074914..2075840 (+)	927	WP_061775218.1	cysteine synthase A	-

Sequence

Protein

• Length: 198 a.a.
• Molecular weight: 21777.83 Da
• Isoelectric Point: 4.8744

>NTDB_id=414658 GU336_RS10140 WP_061775221.1 2070871..2071467(-) (clpP) [Lactococcus raffinolactis strain Lr_19_5]
MALIPTVIEQSSRGERAYDIYSRLLKDRIIMLTGEVEDNMANAVIAQLLFLDAQDSTKDIYLYINSPGGSVSAGLAIVDT
MNFIKSDVQTIVMGVAASMGTIIASSGAKGKRFMLPNAEYLIHQPMGGTGGGTQQTDMQIVADHLSRTRKTLEKILADNS
GQTVNKVHKDAERDRWMSAEETLEYGFIDEIMNRNDLK

Nucleotide

• Length: 597 bp

>NTDB_id=414658 GU336_RS10140 WP_061775221.1 2070871..2071467(-) (clpP) [Lactococcus raffinolactis strain Lr_19_5]
ATGGCACTCATTCCTACAGTCATTGAACAATCAAGCCGCGGTGAACGCGCGTATGATATTTATTCACGTCTTTTGAAAGA
CAGAATCATTATGTTGACAGGAGAAGTTGAAGACAACATGGCTAATGCAGTCATTGCGCAGCTTTTATTCCTTGATGCGC
AAGATTCAACGAAAGATATTTATCTCTATATCAATTCACCAGGTGGCTCAGTCTCTGCTGGTCTTGCGATTGTCGATACC
ATGAACTTCATCAAATCTGATGTTCAAACCATTGTCATGGGCGTTGCGGCGTCTATGGGCACGATTATCGCGTCTTCAGG
GGCCAAAGGTAAACGTTTCATGTTGCCAAATGCTGAATATTTGATTCACCAACCAATGGGCGGTACAGGTGGCGGTACGC
AACAAACAGATATGCAAATCGTCGCAGATCACTTGTCAAGAACGCGTAAAACATTGGAAAAAATCTTGGCAGATAACTCT
GGTCAAACGGTCAATAAAGTCCATAAAGATGCGGAACGTGATCGCTGGATGTCAGCAGAAGAAACTTTAGAATATGGCTT
CATTGATGAAATCATGAACCGTAACGACTTAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-194)

3D structure

• AlphaFold DB: A0A290PWM7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pneumoniae TIGR4	85.641	98.485	0.843
clpP	Streptococcus pneumoniae Rx1	85.641	98.485	0.843
clpP	Streptococcus pneumoniae D39	85.641	98.485	0.843
clpP	Streptococcus pneumoniae R6	85.641	98.485	0.843
clpP	Streptococcus mutans UA159	84.264	99.495	0.838
clpP	Streptococcus thermophilus LMD-9	84.184	98.99	0.833
clpP	Streptococcus thermophilus LMG 18311	84.184	98.99	0.833
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	84.184	98.99	0.833
clpP	Lactococcus lactis subsp. cremoris KW2	83.673	98.99	0.828
clpP	Streptococcus pyogenes MGAS315	83.163	98.99	0.823
clpP	Streptococcus pyogenes JRS4	83.163	98.99	0.823
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	59.067	97.475	0.576
clpP	Bacillus subtilis subsp. subtilis str. 168	56.566	100	0.566