Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   HMPREF0833_RS08300 Genome accession   NC_015678
Coordinates   1783086..1784117 (+) Length   343 a.a.
NCBI ID   WP_115276785.1    Uniprot ID   -
Organism   Streptococcus parasanguinis ATCC 15912     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1778086..1789117
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF0833_RS08275 (HMPREF0833_11651) - 1778155..1778943 (+) 789 WP_013904482.1 hypothetical protein -
  HMPREF0833_RS08280 (HMPREF0833_11652) - 1779086..1780396 (+) 1311 WP_013904483.1 glycosyltransferase -
  HMPREF0833_RS08285 (HMPREF0833_11653) - 1780405..1781508 (+) 1104 WP_013904484.1 glycosyl hydrolase family 8 -
  HMPREF0833_RS08290 (HMPREF0833_11654) - 1781734..1782126 (+) 393 WP_037617571.1 DUF1033 family protein -
  HMPREF0833_RS08295 (HMPREF0833_11655) comYA 1782212..1783153 (+) 942 WP_013904485.1 competence type IV pilus ATPase ComGA Machinery gene
  HMPREF0833_RS08300 (HMPREF0833_11656) comYB 1783086..1784117 (+) 1032 WP_115276785.1 competence type IV pilus assembly protein ComGB Machinery gene
  HMPREF0833_RS08305 (HMPREF0833_11657) comYC 1784114..1784431 (+) 318 WP_003019171.1 competence type IV pilus major pilin ComGC Machinery gene
  HMPREF0833_RS08310 (HMPREF0833_11658) comYD 1784421..1784825 (+) 405 WP_041818518.1 competence type IV pilus minor pilin ComGD Machinery gene
  HMPREF0833_RS08315 (HMPREF0833_11659) comGE 1784791..1785078 (+) 288 WP_013904488.1 competence type IV pilus minor pilin ComGE -
  HMPREF0833_RS08320 (HMPREF0833_11660) comGF/cglF 1785068..1785520 (+) 453 WP_003019060.1 competence type IV pilus minor pilin ComGF Machinery gene
  HMPREF0833_RS08325 (HMPREF0833_11661) comGG 1785477..1785944 (+) 468 WP_255309063.1 competence type IV pilus minor pilin ComGG -
  HMPREF0833_RS08330 (HMPREF0833_11662) comYH 1785975..1786928 (+) 954 WP_013904490.1 class I SAM-dependent methyltransferase Machinery gene
  HMPREF0833_RS08335 (HMPREF0833_11663) - 1786980..1788173 (+) 1194 WP_013904491.1 acetate kinase -
  HMPREF0833_RS08340 (HMPREF0833_11664) - 1788246..1788977 (+) 732 WP_013904492.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 39232.14 Da        Isoelectric Point: 9.5419

>NTDB_id=41399 HMPREF0833_RS08300 WP_115276785.1 1783086..1784117(+) (comYB) [Streptococcus parasanguinis ATCC 15912]
MSWLNRDISSWLRRKPKKLSTAKQKQIIELFLNLYSSGFHLSEIVDFLGRSHLVESRLVSQMREDLSRGKSFSDMMAGIG
FSDAVTTQLSLAELHGNLALSLEKISAYLENMCKVKKKLIEVSTYPLILLGFLVLIMLGLRNYLLPQMDAQNIGTQLISS
FPQLFLALGAGLVTFFLLGFLYYRQSGKINVFRTLSHLPFGKGMIQAYLTAYYAREWGNLIGQGLELSQIFSMMQEQKSQ
LFQEIGRDLALSLDRGQSFSETVRGYPFFKKELPLMIEYGEVKSKLGSELEIYAEKTWEDFFRRVHKAMNVIQPLVFVFV
ALVIVLLYAAMLLPIYQNMEVHL

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=41399 HMPREF0833_RS08300 WP_115276785.1 1783086..1784117(+) (comYB) [Streptococcus parasanguinis ATCC 15912]
ATCTCTTGGCTCAATCGGGATATATCCAGCTGGCTCAGGCGCAAGCCGAAAAAATTATCTACCGCTAAACAAAAGCAAAT
CATCGAATTATTTTTGAATCTTTATTCGAGTGGTTTTCATCTGTCTGAGATCGTCGATTTTCTGGGTCGCTCCCACCTAG
TGGAGAGTCGGTTGGTCTCTCAGATGCGGGAAGATCTCTCTCGTGGGAAGAGTTTCTCAGATATGATGGCGGGGATCGGT
TTTTCAGATGCGGTCACGACACAGCTGTCTCTCGCTGAGCTCCATGGCAATCTTGCATTGAGCTTGGAGAAAATCAGTGC
TTACTTAGAAAACATGTGCAAGGTCAAGAAAAAGCTGATTGAGGTCAGCACTTATCCTCTTATCTTGCTTGGATTTTTGG
TTCTGATTATGCTAGGCTTGCGCAATTATTTGCTCCCTCAAATGGATGCTCAAAATATTGGGACGCAATTGATCAGTTCC
TTCCCCCAACTCTTTTTGGCCTTAGGAGCGGGACTGGTGACCTTCTTCTTACTCGGCTTTCTCTATTACCGCCAGTCAGG
CAAGATCAACGTTTTTAGAACTTTGTCTCATCTGCCTTTCGGGAAAGGCATGATTCAAGCTTATTTGACAGCCTATTATG
CCAGAGAATGGGGAAATCTGATTGGGCAAGGATTGGAATTGTCTCAGATTTTTTCCATGATGCAGGAGCAAAAATCCCAG
CTTTTTCAAGAAATTGGAAGGGATTTAGCTCTTTCTTTAGATCGTGGCCAGTCCTTTTCAGAGACGGTCAGGGGGTATCC
TTTTTTCAAAAAAGAATTGCCCCTTATGATTGAATATGGTGAAGTCAAATCAAAGCTCGGAAGTGAGCTAGAAATCTACG
CTGAAAAAACCTGGGAAGATTTCTTTCGTCGGGTTCACAAGGCTATGAATGTGATACAACCTTTGGTGTTTGTCTTTGTA
GCTCTTGTGATTGTGTTACTCTATGCAGCCATGTTGCTGCCGATTTATCAAAATATGGAGGTTCATTTATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(214-334)

Type II secretion system (T2SS), protein F (T2SSF)

(28-146)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

65.889

100

0.659
  comGB/cglB Streptococcus mitis SK321

66.369

97.959

0.65
  comGB/cglB Streptococcus mitis NCTC 12261

65.774

97.959

0.644
  comGB/cglB Streptococcus pneumoniae TIGR4

65.476

97.959

0.641
  comGB/cglB Streptococcus pneumoniae R6

65.476

97.959

0.641
  comGB/cglB Streptococcus pneumoniae Rx1

65.476

97.959

0.641
  comGB/cglB Streptococcus pneumoniae D39

65.476

97.959

0.641
  comYB Streptococcus mutans UA159

57.307

100

0.583
  comYB Streptococcus mutans UA140

57.307

100

0.583
  comGB Lactococcus lactis subsp. cremoris KW2

48.665

98.251

0.478

Multiple sequence alignment