Detailed information NTG0041382

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: HMPREF0833_RS04775
• Genome accession: NC_015678
• Coordinates: 1002868..1003458 (-)
• Length: 196 a.a.
• NCBI ID: WP_013903962.1
• Uniprot ID: F8DJ91
• Organism: Streptococcus parasanguinis ATCC 15912
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 997868..1008458

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF0833_RS04750 (HMPREF0833_10963)	-	998380..999144 (-)	765	WP_003005595.1	ABC transporter ATP-binding protein	-
HMPREF0833_RS04755 (HMPREF0833_10964)	-	999144..1000091 (-)	948	WP_013903960.1	branched-chain amino acid ABC transporter permease	-
HMPREF0833_RS04760 (HMPREF0833_10965)	-	1000095..1000964 (-)	870	WP_021153669.1	branched-chain amino acid ABC transporter permease	-
HMPREF0833_RS04765 (HMPREF0833_10966)	-	1001046..1002203 (-)	1158	WP_003016149.1	ABC transporter substrate-binding protein	-
HMPREF0833_RS04770 (HMPREF0833_10967)	-	1002312..1002590 (-)	279	WP_003013098.1	DUF2129 domain-containing protein	-
HMPREF0833_RS04775 (HMPREF0833_10968)	clpP	1002868..1003458 (-)	591	WP_013903962.1	ATP-dependent Clp protease proteolytic subunit	Regulator
HMPREF0833_RS04780 (HMPREF0833_10969)	upp	1003588..1004217 (-)	630	WP_003005574.1	uracil phosphoribosyltransferase	-
HMPREF0833_RS04785 (HMPREF0833_10970)	mgtA	1004437..1007097 (-)	2661	WP_013903963.1	magnesium-translocating P-type ATPase	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21483.53 Da
• Isoelectric Point: 4.5843

>NTDB_id=41382 HMPREF0833_RS04775 WP_013903962.1 1002868..1003458(-) (clpP) [Streptococcus parasanguinis ATCC 15912]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMVTGPVEDQMANSIIAQLLFLDAQDNTKDIYMYINTPGGSVSAGLAIVDTMN
FIKSDVQTIVMGMAASMGTIIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNNLEKILANNSGQ
SIEKVHADAERDNWMSAQETLEYGFIDEIMANNKLD

Nucleotide

• Length: 591 bp

>NTDB_id=41382 HMPREF0833_RS04775 WP_013903962.1 1002868..1003458(-) (clpP) [Streptococcus parasanguinis ATCC 15912]
ATGATTCCAGTAGTTATTGAACAAACCAGTCGTGGAGAGCGTTCTTACGATATTTATTCCCGTCTGTTGAAAGATCGAAT
TATCATGGTAACAGGACCAGTTGAGGACCAAATGGCTAACTCCATTATCGCTCAATTGCTCTTCTTGGATGCCCAAGATA
ATACAAAAGATATCTATATGTATATCAATACTCCAGGTGGCTCTGTCTCTGCAGGTCTCGCCATCGTAGATACCATGAAC
TTTATCAAGTCAGATGTCCAAACTATTGTTATGGGGATGGCGGCTTCTATGGGAACTATCATTGCTTCAAGCGGTGCGAA
GGGCAAACGCTTCATGTTGCCAAATGCAGAGTACATGATTCACCAACCAATGGGTGGTACTGGTGGTGGTACCCAACAAA
CCGATATGGCGATCGCAGCAGAACACTTGCTCAAAACACGGAATAACTTGGAAAAAATCCTTGCGAACAATTCAGGTCAA
TCCATTGAAAAAGTGCATGCTGATGCTGAACGTGACAATTGGATGAGCGCGCAAGAAACACTTGAATATGGCTTTATTGA
TGAAATCATGGCCAATAATAAATTGGACTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: F8DJ91

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus thermophilus LMG 18311	93.846	99.49	0.934
clpP	Streptococcus thermophilus LMD-9	93.846	99.49	0.934
clpP	Streptococcus pneumoniae Rx1	93.367	100	0.934
clpP	Streptococcus pneumoniae D39	93.367	100	0.934
clpP	Streptococcus pneumoniae R6	93.367	100	0.934
clpP	Streptococcus pneumoniae TIGR4	93.367	100	0.934
clpP	Streptococcus pyogenes JRS4	88.205	99.49	0.878
clpP	Streptococcus pyogenes MGAS315	88.205	99.49	0.878
clpP	Streptococcus mutans UA159	87.692	99.49	0.872
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	85.128	99.49	0.847
clpP	Lactococcus lactis subsp. cremoris KW2	84.615	99.49	0.842
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.031	98.469	0.571
clpP	Bacillus subtilis subsp. subtilis str. 168	57.216	98.98	0.566