Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   HMPREF0833_RS04465 Genome accession   NC_015678
Coordinates   932897..933598 (-) Length   233 a.a.
NCBI ID   WP_003015620.1    Uniprot ID   A0AAW7NZJ3
Organism   Streptococcus parasanguinis ATCC 15912     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 927897..938598
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF0833_RS04445 (HMPREF0833_10900) rnc 929429..930130 (-) 702 WP_013903906.1 ribonuclease III -
  HMPREF0833_RS04450 (HMPREF0833_10901) - 930230..930616 (-) 387 WP_013903907.1 YbaN family protein -
  HMPREF0833_RS04455 (HMPREF0833_10902) vicX 930735..931544 (-) 810 WP_003015609.1 MBL fold metallo-hydrolase Regulator
  HMPREF0833_RS04460 (HMPREF0833_10903) micB 931552..932904 (-) 1353 WP_013903909.1 cell wall metabolism sensor histidine kinase VicK Regulator
  HMPREF0833_RS04465 (HMPREF0833_10904) micA 932897..933598 (-) 702 WP_003015620.1 response regulator YycF Regulator
  HMPREF0833_RS04470 (HMPREF0833_10905) thrS 933755..935698 (-) 1944 WP_013903910.1 threonine--tRNA ligase -
  HMPREF0833_RS04475 (HMPREF0833_10906) - 936052..937374 (-) 1323 WP_013903911.1 glycosyltransferase family 4 protein -
  HMPREF0833_RS04480 (HMPREF0833_10907) - 937376..938374 (-) 999 WP_013903912.1 glycosyltransferase family 4 protein -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26662.44 Da        Isoelectric Point: 4.5983

>NTDB_id=41380 HMPREF0833_RS04465 WP_003015620.1 932897..933598(-) (micA) [Streptococcus parasanguinis ATCC 15912]
MKKILVVDDEKPISDIIKFNMAKEGYEVLTAFDGREALEVFAAENPDVIILDLMLPEIDGLEVARTIRKTSNVPIIVLSA
KDTEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSEFAADPQLENDADTEIVIGDLHILPDAFLVQKGNKELDLTH
REFELLYHLATHVGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPGRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=41380 HMPREF0833_RS04465 WP_003015620.1 932897..933598(-) (micA) [Streptococcus parasanguinis ATCC 15912]
ATGAAAAAAATATTAGTAGTTGATGATGAAAAACCAATTTCAGACATTATCAAATTTAACATGGCGAAAGAGGGCTATGA
GGTATTGACAGCCTTTGATGGTCGGGAAGCATTGGAAGTCTTTGCAGCTGAAAATCCAGATGTTATTATTCTAGATTTGA
TGTTACCAGAGATTGATGGTTTGGAAGTGGCGCGGACGATTCGTAAGACCAGTAATGTGCCGATCATTGTCCTATCTGCC
AAGGATACGGAATTTGATAAGGTCATTGGGCTTGAAATTGGGGCAGATGACTATGTGACCAAACCCTTCTCGAATCGGGA
ATTGCAAGCGCGTGTGAAAGCCTTGTTGCGTCGTTCTGAGTTTGCGGCTGATCCTCAGCTTGAAAATGATGCCGATACGG
AAATTGTCATTGGTGATCTTCACATTCTTCCAGATGCTTTTTTGGTTCAAAAAGGCAACAAAGAATTGGACTTGACCCAT
CGCGAATTTGAATTGCTCTATCACCTTGCGACCCATGTTGGTCAAGTGATGACCCGTGAGCACCTTCTTGAGACGGTGTG
GGGCTATGATTACTTTGGTGATGTTCGGACAGTGGACGTGACGGTTCGTCGTTTGCGTGAAAAAATCGAGGACACACCGG
GACGTCCAGAATATATCTTGACTCGCCGTGGTGTTGGATATTATATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.974

100

0.82
  vicR Streptococcus mutans UA159

78.298

100

0.79
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

98.712

0.455
  covR Streptococcus salivarius strain HSISS4

43.668

98.283

0.429
  scnR Streptococcus mutans UA159

36.522

98.712

0.361

Multiple sequence alignment