Detailed information NTG0041379

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: HMPREF0833_RS04460
• Genome accession: NC_015678
• Coordinates: 931552..932904 (-)
• Length: 450 a.a.
• NCBI ID: WP_013903909.1
• Uniprot ID: F8DJC8
• Organism: Streptococcus parasanguinis ATCC 15912
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 926552..937904

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF0833_RS04445 (HMPREF0833_10900)	rnc	929429..930130 (-)	702	WP_013903906.1	ribonuclease III	-
HMPREF0833_RS04450 (HMPREF0833_10901)	-	930230..930616 (-)	387	WP_013903907.1	YbaN family protein	-
HMPREF0833_RS04455 (HMPREF0833_10902)	vicX	930735..931544 (-)	810	WP_003015609.1	MBL fold metallo-hydrolase	Regulator
HMPREF0833_RS04460 (HMPREF0833_10903)	micB	931552..932904 (-)	1353	WP_013903909.1	cell wall metabolism sensor histidine kinase VicK	Regulator
HMPREF0833_RS04465 (HMPREF0833_10904)	micA	932897..933598 (-)	702	WP_003015620.1	response regulator YycF	Regulator
HMPREF0833_RS04470 (HMPREF0833_10905)	thrS	933755..935698 (-)	1944	WP_013903910.1	threonine--tRNA ligase	-
HMPREF0833_RS04475 (HMPREF0833_10906)	-	936052..937374 (-)	1323	WP_013903911.1	glycosyltransferase family 4 protein	-

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51159.32 Da
• Isoelectric Point: 4.5621

>NTDB_id=41379 HMPREF0833_RS04460 WP_013903909.1 931552..932904(-) (micB) [Streptococcus parasanguinis ATCC 15912]
MIDQLKQFVMSSNFVFVLITVGFIIVVALLLLENRRDNIKLRQLNSKIKDLIAGDYSEVVDMQGSPELTDMTNSINDLSE
VIRLTHENLEQETKRLTSILSYMTDGVLATNRRGQIIMVNEMAAKQLNVNPDEVLNTSILDLLSLGDDYDLRSLITEVPE
LTIDSQDENGEYISLRVRFALIRRESGFISGLVAVLHDTTEQDKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALS
EPVAPDFVKVSLNETNRMMRMVTDLLSLSRIDNETSQLDIELTNFTAFITFILNRFDKIKSQSQEDTKKYELIREYPITP
IWVEIDTDKMTQVIDNILNNAIKYSPDGGKIKVGMRTTDAQLIISISDEGLGIPKKDLPRIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAIKDDWDTEEEE

Nucleotide

• Length: 1353 bp

>NTDB_id=41379 HMPREF0833_RS04460 WP_013903909.1 931552..932904(-) (micB) [Streptococcus parasanguinis ATCC 15912]
ATGATTGATCAACTAAAACAATTTGTAATGTCGTCGAACTTTGTCTTTGTTCTGATTACGGTTGGGTTTATCATTGTGGT
AGCCTTGCTTTTGCTAGAAAACCGTAGGGACAATATCAAGCTCAGACAATTAAACTCCAAAATTAAAGATCTGATTGCAG
GGGACTATTCCGAAGTGGTCGACATGCAAGGAAGTCCAGAGCTGACAGATATGACCAATAGCATTAATGATCTGTCTGAG
GTTATTCGCCTGACGCATGAAAACTTGGAACAAGAAACCAAGCGTTTGACCAGTATCCTTTCTTACATGACAGATGGGGT
GCTTGCGACCAACAGACGTGGTCAGATCATCATGGTCAATGAAATGGCAGCCAAGCAATTGAATGTTAATCCAGATGAGG
TGCTCAATACCAGTATTCTGGATTTGCTTTCGCTTGGGGATGACTATGATCTGCGAAGCTTGATTACTGAAGTACCAGAG
TTGACCATTGATTCCCAGGATGAAAATGGAGAATACATAAGTCTTCGTGTGCGCTTTGCCTTGATTCGTCGCGAGTCAGG
TTTTATCTCTGGTCTGGTAGCTGTCTTGCACGATACGACAGAGCAGGACAAGGAAGAGCGGGAACGTCGCCTCTTTGTCT
CCAATGTGAGTCATGAATTACGGACACCTTTGACCAGTGTGAAATCCTATCTGGAAGCCCTAGACGATGGCGCTTTGTCA
GAGCCGGTAGCACCAGATTTTGTCAAGGTTTCACTCAATGAAACCAACCGCATGATGCGCATGGTCACAGATCTATTGAG
CTTGTCACGAATCGATAATGAAACCAGTCAGTTGGACATCGAGTTGACCAACTTTACGGCCTTTATCACCTTTATTTTGA
ACCGCTTTGATAAGATCAAGAGTCAATCGCAAGAAGATACCAAGAAGTATGAACTAATCCGAGAATACCCGATCACTCCA
ATCTGGGTGGAAATTGATACGGATAAAATGACCCAGGTGATCGATAATATCTTGAACAATGCCATCAAGTACTCACCTGA
TGGTGGAAAGATCAAGGTAGGGATGAGAACAACAGATGCCCAGTTGATTATTTCCATCTCAGATGAGGGTTTGGGGATTC
CCAAGAAAGACTTGCCACGCATTTTTGATCGCTTTTACCGAGTGGATAAGGCGCGTAGCCGGGCCCAAGGTGGGACTGGT
CTGGGCTTAGCCATTGCTAAGGAGATCATTAAACAACACAAAGGCTTTATTTGGGCCAAGAGTGAATATGGCAAGGGATC
TACCTTTACCATTGTCTTGCCGTATGACAAAGATGCTATTAAAGACGACTGGGATACAGAAGAGGAAGAATAA

Domains

Predicted by InterproScan.

• PAS fold (PAS) (96-198)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (326-436)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

3D structure

• AlphaFold DB: F8DJC8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	78.685	98	0.771
vicK	Streptococcus mutans UA159	71.007	90.444	0.642