Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   HMPREF0833_RS02650 Genome accession   NC_015678
Coordinates   536075..536923 (-) Length   282 a.a.
NCBI ID   WP_013903585.1    Uniprot ID   F8DH71
Organism   Streptococcus parasanguinis ATCC 15912     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 531075..541923
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF0833_RS02635 (HMPREF0833_10519) - 532428..533133 (-) 706 Protein_513 DUF3307 domain-containing protein -
  HMPREF0833_RS02640 (HMPREF0833_10520) - 533117..533794 (-) 678 WP_013903583.1 SatD family protein -
  HMPREF0833_RS02645 (HMPREF0833_10521) topA 533901..535988 (-) 2088 WP_013903584.1 type I DNA topoisomerase -
  HMPREF0833_RS02650 (HMPREF0833_10522) dprA/cilB/dalA 536075..536923 (-) 849 WP_013903585.1 DNA-processing protein DprA Machinery gene
  HMPREF0833_RS02655 (HMPREF0833_10523) - 536983..537912 (-) 930 WP_013903586.1 ROK family protein -
  HMPREF0833_RS02660 (HMPREF0833_10524) - 537916..538683 (-) 768 WP_013903587.1 ribonuclease HII -
  HMPREF0833_RS02665 (HMPREF0833_10525) ylqF 538670..539521 (-) 852 WP_041818199.1 ribosome biogenesis GTPase YlqF -
  HMPREF0833_RS02670 (HMPREF0833_10526) - 539635..539973 (-) 339 WP_006597242.1 ATP cone domain-containing protein -
  HMPREF0833_RS02675 (HMPREF0833_10527) dapA 540150..541085 (-) 936 WP_041818201.1 4-hydroxy-tetrahydrodipicolinate synthase -

Sequence

Protein


Download         Length: 282 a.a.        Molecular weight: 31655.48 Da        Isoelectric Point: 6.8235

>NTDB_id=41374 HMPREF0833_RS02650 WP_013903585.1 536075..536923(-) (dprA/cilB/dalA) [Streptococcus parasanguinis ATCC 15912]
MEKFEIFKLKEAGLSNEQVLRVLDYCRKGQVLPSLEEIARIARCRSILHFVDKYRQLDEDHLHKEFERFPSLSIFDPEYP
EELLQIYNPPVILFYQGNLQLLTRPKIAVVGARETTREGVRSVEKIIKELGNELVIVSGLAKGIDATAHYASIRNGGKTI
GVIGTGLDVFYPKSNQRLQAHMGEHHLILSEYGPGQAPLKFHFPERNRIIAGLCQAVIVAEARLRSGSLITCERAMEEGR
DVFAIPGNILDGKSAGCHHLIQEGAKLVTSGQDILDELKYEL

Nucleotide


Download         Length: 849 bp        

>NTDB_id=41374 HMPREF0833_RS02650 WP_013903585.1 536075..536923(-) (dprA/cilB/dalA) [Streptococcus parasanguinis ATCC 15912]
ATGGAGAAATTTGAAATCTTTAAATTAAAAGAAGCCGGTTTATCAAATGAGCAAGTCTTGAGAGTTTTGGACTACTGTAG
AAAAGGCCAAGTCTTACCAAGCTTAGAAGAGATAGCAAGGATCGCTCGCTGTCGCAGTATCCTTCATTTTGTAGACAAAT
ACCGACAACTGGATGAAGACCATTTACACAAGGAGTTCGAACGGTTCCCATCTCTATCCATTTTTGATCCTGAATACCCT
GAGGAATTGCTACAGATCTACAACCCTCCTGTAATCCTTTTTTACCAAGGGAATTTGCAACTGCTAACCAGACCGAAGAT
TGCAGTCGTAGGAGCTCGGGAGACAACGCGAGAAGGGGTGCGATCTGTAGAGAAAATTATTAAGGAACTTGGGAATGAAC
TTGTCATTGTTAGTGGGCTTGCAAAGGGGATTGATGCGACAGCTCATTATGCCAGCATTCGAAATGGTGGCAAGACCATC
GGAGTGATAGGAACGGGACTGGATGTCTTTTATCCTAAGAGCAATCAAAGACTGCAGGCGCATATGGGGGAACACCATCT
GATCTTGAGCGAGTATGGTCCAGGGCAGGCACCACTTAAGTTTCATTTTCCAGAGCGAAATCGCATCATTGCAGGCCTCT
GTCAGGCTGTGATTGTGGCAGAAGCTCGACTCCGTTCAGGGAGTTTGATTACTTGTGAGCGTGCTATGGAAGAAGGCCGA
GACGTTTTTGCTATTCCAGGAAATATTTTAGATGGAAAATCTGCAGGCTGCCATCACTTGATTCAAGAAGGCGCAAAGCT
TGTCACATCAGGCCAGGACATTCTTGATGAATTGAAATACGAATTGTGA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-62)

DNA recombination-mediator protein A (DNA_processg_A)

(72-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F8DH71

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

65.357

99.291

0.649
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

65

99.291

0.645
  dprA/cilB/dalA Streptococcus pneumoniae D39

65

99.291

0.645
  dprA/cilB/dalA Streptococcus pneumoniae R6

65

99.291

0.645
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

65

99.291

0.645
  dprA/cilB/dalA Streptococcus mitis SK321

64.643

99.291

0.642
  dprA Streptococcus mutans UA159

61.429

99.291

0.61
  dprA Lactococcus lactis subsp. cremoris KW2

53.025

99.645

0.528
  dprA Bacillus subtilis subsp. subtilis str. 168

40.21

100

0.408
  dprA Legionella pneumophila strain ERS1305867

44.444

82.979

0.369

Multiple sequence alignment