Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   GQY29_RS04095 Genome accession   NZ_CP047191
Coordinates   754498..755598 (+) Length   366 a.a.
NCBI ID   WP_159340986.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain EU01     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 749498..760598
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GQY29_RS04085 (GQY29_04085) - 753232..753594 (+) 363 WP_023909982.1 DUF1033 family protein -
  GQY29_RS04090 (GQY29_04090) comYA 753675..754616 (+) 942 WP_014622005.1 competence type IV pilus ATPase ComGA Machinery gene
  GQY29_RS04095 (GQY29_04095) comYB 754498..755598 (+) 1101 WP_159340986.1 competence type IV pilus assembly protein ComGB Machinery gene
  GQY29_RS04100 (GQY29_04100) comYC 755595..755921 (+) 327 WP_023909980.1 competence type IV pilus major pilin ComGC Machinery gene
  GQY29_RS04105 (GQY29_04105) comYD 755881..756309 (+) 429 WP_171815055.1 competence type IV pilus minor pilin ComGD Machinery gene
  GQY29_RS04110 (GQY29_04110) comGE 756281..756574 (+) 294 WP_023909978.1 competence type IV pilus minor pilin ComGE -
  GQY29_RS04115 (GQY29_04115) comYF 756558..756995 (+) 438 WP_084825661.1 competence type IV pilus minor pilin ComGF Machinery gene
  GQY29_RS04120 (GQY29_04120) comGG 756973..757290 (+) 318 WP_023909975.1 competence type IV pilus minor pilin ComGG -
  GQY29_RS04125 (GQY29_04125) comYH 757335..758291 (+) 957 WP_023909974.1 class I SAM-dependent methyltransferase Machinery gene
  GQY29_RS04130 (GQY29_04130) - 758347..759540 (+) 1194 WP_084825660.1 acetate kinase -
  GQY29_RS04135 (GQY29_04135) - 759788..759985 (+) 198 WP_159340988.1 helix-turn-helix transcriptional regulator -
  GQY29_RS10680 (GQY29_04140) - 759997..760272 (+) 276 WP_100273190.1 CAAX protease -

Sequence

Protein


Download         Length: 366 a.a.        Molecular weight: 41841.92 Da        Isoelectric Point: 10.0777

>NTDB_id=411385 GQY29_RS04095 WP_159340986.1 754498..755598(+) (comYB) [Streptococcus thermophilus strain EU01]
MPEKISKTIRRPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVTQLFKQLLKAGFTLTEIVAFLERSHLLKETSLSLM
KESLIRGDRLDQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASYPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide


Download         Length: 1101 bp        

>NTDB_id=411385 GQY29_RS04095 WP_159340986.1 754498..755598(+) (comYB) [Streptococcus thermophilus strain EU01]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTACCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAACATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGGATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCTGAACGTATTGCCAGTTATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGCTATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(52-164)

Type II secretion system (T2SS), protein F (T2SSF)

(236-356)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

54.678

93.443

0.511
  comYB Streptococcus mutans UA159

54.678

93.443

0.511
  comYB Streptococcus gordonii str. Challis substr. CH1

51.17

93.443

0.478
  comGB/cglB Streptococcus mitis NCTC 12261

50.453

90.437

0.456
  comGB/cglB Streptococcus mitis SK321

49.697

90.164

0.448
  comGB/cglB Streptococcus pneumoniae Rx1

49.695

89.617

0.445
  comGB/cglB Streptococcus pneumoniae D39

49.695

89.617

0.445
  comGB/cglB Streptococcus pneumoniae R6

49.695

89.617

0.445
  comGB/cglB Streptococcus pneumoniae TIGR4

49.695

89.617

0.445
  comGB Lactococcus lactis subsp. cremoris KW2

45.455

90.164

0.41

Multiple sequence alignment