Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   SGPB_RS05250 Genome accession   NC_015600
Coordinates   1046388..1047062 (-) Length   224 a.a.
NCBI ID   WP_013851854.1    Uniprot ID   A0AAW6YDN2
Organism   Streptococcus pasteurianus ATCC 43144     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1041388..1052062
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGPB_RS05225 (SGPB_0996) deoC 1041846..1042508 (-) 663 WP_013851852.1 deoxyribose-phosphate aldolase -
  SGPB_RS05230 (SGPB_0997) - 1042963..1043556 (-) 594 WP_003064873.1 class I SAM-dependent methyltransferase -
  SGPB_RS05235 (SGPB_0998) coaA 1043672..1044592 (+) 921 WP_013851853.1 type I pantothenate kinase -
  SGPB_RS05240 (SGPB_0999) rpsT 1044667..1044918 (+) 252 WP_003064878.1 30S ribosomal protein S20 -
  SGPB_RS05245 (SGPB_1000) ciaH 1045058..1046398 (-) 1341 WP_003064880.1 sensor histidine kinase Regulator
  SGPB_RS05250 (SGPB_1001) ciaR 1046388..1047062 (-) 675 WP_013851854.1 response regulator transcription factor Regulator
  SGPB_RS05255 (SGPB_1002) - 1047255..1049798 (-) 2544 WP_003064884.1 M1 family metallopeptidase -
  SGPB_RS05260 (SGPB_1003) phoU 1050021..1050674 (-) 654 WP_003064885.1 phosphate signaling complex protein PhoU -
  SGPB_RS05265 (SGPB_1004) pstB 1050706..1051464 (-) 759 WP_013851855.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25427.14 Da        Isoelectric Point: 4.3831

>NTDB_id=41078 SGPB_RS05250 WP_013851854.1 1046388..1047062(-) (ciaR) [Streptococcus pasteurianus ATCC 43144]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKDGFQVLKELREKSVSTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFSDNNLSYGELTVTTSTNTTTINGKEVEMLGKEFDLLVY
FLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFAKNLQTLRSVGYILKNAE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=41078 SGPB_RS05250 WP_013851854.1 1046388..1047062(-) (ciaR) [Streptococcus pasteurianus ATCC 43144]
ATGATTAAAATATTATTAGTAGAAGACGATTTGAGTTTATCTAATTCCATTTTTGATTTTTTAGACGATTTTGCTGATGT
AATGCAAGTGTTTGATGGCGAGGAAGGTTTGTATGAAGCAGAGAGTGGTGTATATGACCTTATTCTACTTGACCTAATGT
TACCTGAGAAAGATGGCTTCCAGGTTCTAAAAGAATTACGAGAAAAGTCTGTATCAACACCTGTACTTATTATGACTGCG
AAAGAAAGCCTCGACGATAAAGGACATGGATTTGAGTTGGGAGCTGATGATTATTTAACTAAACCCTTTTACCTTGAGGA
ATTAAAAATGCGTATCCAAGCTCTTTTGAAACGTTCTGGTAAGTTTAGTGATAATAATTTGTCTTATGGAGAGCTAACTG
TTACTACTTCTACTAATACAACAACTATTAATGGTAAAGAAGTGGAAATGCTTGGTAAAGAATTTGACTTGTTGGTTTAT
TTCTTACAAAATCAAAATGTTATTTTACCAAAATCACAAATTTTTGATCGTATTTGGGGCTTTGATAGTGATACAACGAT
TTCGGTTGTTGAGGTTTACGTTTCAAAAATTCGAAAAAAACTTAAAGGCACTACTTTTGCTAAAAACCTTCAGACCCTAC
GGAGTGTAGGTTATATTCTGAAAAATGCTGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

92.377

99.554

0.92
  ciaR Streptococcus pneumoniae Rx1

86.161

100

0.862
  ciaR Streptococcus pneumoniae D39

86.161

100

0.862
  ciaR Streptococcus pneumoniae R6

86.161

100

0.862
  ciaR Streptococcus pneumoniae TIGR4

86.161

100

0.862
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.667

100

0.388
  vicR Streptococcus mutans UA159

35.47

100

0.371
  micA Streptococcus pneumoniae Cp1015

35.622

100

0.371

Multiple sequence alignment