Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   SGPB_RS05245 Genome accession   NC_015600
Coordinates   1045058..1046398 (-) Length   446 a.a.
NCBI ID   WP_003064880.1    Uniprot ID   A0AAW6YHF0
Organism   Streptococcus pasteurianus ATCC 43144     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1040058..1051398
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGPB_RS05220 (SGPB_0995) - 1040587..1041651 (-) 1065 WP_003064867.1 BMP family lipoprotein -
  SGPB_RS05225 (SGPB_0996) deoC 1041846..1042508 (-) 663 WP_013851852.1 deoxyribose-phosphate aldolase -
  SGPB_RS05230 (SGPB_0997) - 1042963..1043556 (-) 594 WP_003064873.1 class I SAM-dependent methyltransferase -
  SGPB_RS05235 (SGPB_0998) coaA 1043672..1044592 (+) 921 WP_013851853.1 type I pantothenate kinase -
  SGPB_RS05240 (SGPB_0999) rpsT 1044667..1044918 (+) 252 WP_003064878.1 30S ribosomal protein S20 -
  SGPB_RS05245 (SGPB_1000) ciaH 1045058..1046398 (-) 1341 WP_003064880.1 sensor histidine kinase Regulator
  SGPB_RS05250 (SGPB_1001) ciaR 1046388..1047062 (-) 675 WP_013851854.1 response regulator transcription factor Regulator
  SGPB_RS05255 (SGPB_1002) - 1047255..1049798 (-) 2544 WP_003064884.1 M1 family metallopeptidase -
  SGPB_RS05260 (SGPB_1003) phoU 1050021..1050674 (-) 654 WP_003064885.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 49991.74 Da        Isoelectric Point: 5.2300

>NTDB_id=41077 SGPB_RS05245 WP_003064880.1 1045058..1046398(-) (ciaH) [Streptococcus pasteurianus ATCC 43144]
MLNKLQKKLSSGTFSHFFHFFAVFTGIFVIMTVIILQIMRYGLYSSVDTSLQNAADNADDYVARTMERSDTLQSDDSSTD
AFSGGTGSSGKAKPSTGGVGLSNVSVLLYDEDGKILNALDAFVQFGTLSTTFDEDSVGEIKEQKITTIFGQTEKYHVLAV
KVSSSEYPSIKYATFLVSVRQLDEANERYVTITITVMVIFWIISVVASVYLANWTRKPIMESYEKQKSFVENASHELRTP
LAVLQNRLESLFRRPDATILDNSESIAASLDEVRNMRILTTNLLNLARRDDGLKVELEDIQPATFNEIFENYDMIAEENG
KTFIGHNLAERPIKSDRTLLKQLMTILFDNAIKYTDDDGVIEFTVKTTDKQTILTVADNGPGISDADKVKIFDRFYRVDK
ARTRQKGGFGLGLSLAKQIVDVLKGDIQVKDNQPKGTIFEVRFNRH

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=41077 SGPB_RS05245 WP_003064880.1 1045058..1046398(-) (ciaH) [Streptococcus pasteurianus ATCC 43144]
ATGCTGAATAAATTACAGAAAAAATTATCATCAGGGACATTTTCACATTTCTTTCATTTCTTTGCTGTCTTTACAGGGAT
TTTTGTCATCATGACAGTGATTATTTTGCAGATTATGCGTTATGGACTTTATTCCTCTGTTGATACGAGTTTGCAAAATG
CAGCAGACAATGCTGATGATTATGTCGCGCGAACTATGGAACGTAGTGATACTTTGCAATCGGACGATTCTTCTACGGAC
GCTTTTTCAGGAGGAACAGGTAGTTCTGGGAAAGCGAAACCTAGTACCGGCGGAGTTGGTCTAAGCAACGTTAGCGTTCT
TCTTTATGATGAAGACGGTAAAATTTTAAATGCTTTGGATGCTTTTGTTCAATTTGGAACCTTATCGACAACTTTTGATG
AAGATAGTGTCGGTGAAATCAAAGAACAGAAGATTACGACCATTTTTGGTCAAACCGAGAAATATCATGTGTTGGCTGTA
AAAGTGAGTAGTAGCGAGTATCCTAGTATAAAATACGCTACTTTCCTTGTTAGTGTTCGTCAGTTAGATGAAGCTAACGA
ACGATACGTGACAATTACGATTACTGTTATGGTTATTTTCTGGATTATTTCGGTCGTAGCAAGTGTTTATCTTGCCAATT
GGACAAGAAAACCAATTATGGAAAGCTATGAAAAACAAAAATCCTTTGTCGAAAATGCTAGTCATGAGTTGCGTACACCG
CTTGCTGTTTTGCAGAATCGTTTAGAAAGTCTCTTTAGGCGACCTGATGCTACAATTTTGGACAATAGTGAAAGTATTGC
TGCCAGTCTAGACGAAGTTCGAAATATGCGAATTCTGACCACAAATCTGTTAAATTTAGCACGTCGTGACGATGGTTTGA
AAGTTGAGTTAGAGGATATTCAACCAGCAACTTTCAATGAAATCTTTGAAAATTACGATATGATTGCTGAAGAAAATGGC
AAGACGTTTATCGGACATAATTTGGCAGAGCGACCAATCAAATCAGACCGTACATTGTTAAAACAACTGATGACTATCTT
ATTTGATAATGCCATAAAATATACCGACGATGATGGTGTCATTGAATTTACTGTTAAAACAACAGATAAACAAACAATTC
TGACAGTTGCTGATAACGGCCCAGGGATTAGCGACGCTGATAAAGTTAAGATTTTTGACCGTTTTTATCGTGTGGATAAA
GCACGGACACGTCAAAAAGGCGGCTTTGGTCTAGGATTGTCACTTGCTAAGCAAATTGTTGATGTTTTAAAAGGCGATAT
TCAAGTCAAAGATAACCAACCAAAAGGAACTATTTTTGAAGTTCGTTTTAATCGTCATTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(227-292)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(336-443)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

59.142

99.327

0.587
  ciaH Streptococcus pneumoniae Rx1

51.467

99.327

0.511
  ciaH Streptococcus pneumoniae D39

51.467

99.327

0.511
  ciaH Streptococcus pneumoniae R6

51.467

99.327

0.511
  ciaH Streptococcus pneumoniae TIGR4

51.467

99.327

0.511

Multiple sequence alignment