Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   GQ677_RS05255 Genome accession   NZ_CP047120
Coordinates   1030778..1031452 (+) Length   224 a.a.
NCBI ID   WP_002984519.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 1085     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1025778..1036452
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GQ677_RS05240 (GQ677_05240) pstB 1026210..1026968 (+) 759 WP_002993892.1 phosphate ABC transporter ATP-binding protein PstB -
  GQ677_RS05245 (GQ677_05245) phoU 1027036..1027689 (+) 654 WP_002984514.1 phosphate signaling complex protein PhoU -
  GQ677_RS05250 (GQ677_05250) - 1027894..1030431 (+) 2538 WP_136273956.1 M1 family metallopeptidase -
  GQ677_RS05255 (GQ677_05255) ciaR 1030778..1031452 (+) 675 WP_002984519.1 response regulator transcription factor Regulator
  GQ677_RS05260 (GQ677_05260) ciaH 1031445..1032755 (+) 1311 WP_011054528.1 cell wall metabolism sensor histidine kinase WalK Regulator
  GQ677_RS05265 (GQ677_05265) rpsT 1032880..1033128 (-) 249 WP_009881183.1 30S ribosomal protein S20 -
  GQ677_RS05270 (GQ677_05270) coaA 1033182..1034102 (-) 921 WP_010922353.1 type I pantothenate kinase -
  GQ677_RS05275 (GQ677_05275) - 1034370..1034963 (+) 594 WP_010922352.1 class I SAM-dependent methyltransferase -
  GQ677_RS05280 (GQ677_05280) - 1035616..1036005 (+) 390 WP_011285547.1 cytidine deaminase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25703.91 Da        Isoelectric Point: 4.7287

>NTDB_id=410740 GQ677_RS05255 WP_002984519.1 1030778..1031452(+) (ciaR) [Streptococcus pyogenes strain 1085]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGLYEAESGIYDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTA
KEGLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRTGKFADKNISFGNLVVDLARKEVKVEGKVVELLGKEFDLLVY
LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYISKIRKKLKGTRFVNRLQTLRSVGYILKNNE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=410740 GQ677_RS05255 WP_002984519.1 1030778..1031452(+) (ciaR) [Streptococcus pyogenes strain 1085]
ATGATAAAAATATTATTAGTAGAAGATGACTTGAGCTTATCAAATTCCATTTTTGATTTTTTAGATGATTTTGCAGACGT
CATGCAAGTTTTTGATGGCGATGAAGGTTTATACGAAGCAGAAAGTGGTATTTATGATTTGATTTTGTTAGACCTTATGT
TGCCGGAGAAAAATGGCTTTCAAGTCTTAAAAGAATTGCGAGAAAAAGATATTAAAATTCCTGTATTGATCATGACAGCT
AAAGAGGGTTTAGATGATAAAGGTCACGGATTTGAATTAGGTGCTGATGATTATCTGACAAAGCCGTTCTATTTAGAAGA
GTTAAAAATGCGAATTCAAGCACTGTTAAAAAGAACAGGGAAATTTGCAGATAAAAATATTAGTTTTGGCAATTTAGTGG
TCGACTTAGCTCGAAAAGAGGTGAAGGTTGAAGGGAAAGTAGTTGAATTACTTGGCAAAGAATTTGATTTGTTGGTGTAT
CTTTTGCAAAATCAAAACGTTATTTTACCAAAGACACAAATTTTTGATCGTTTATGGGGATTCGATAGTGATACTACGAT
TTCGGTTGTTGAAGTTTACATTTCTAAAATAAGGAAAAAATTAAAAGGTACCCGTTTTGTTAACAGGCTTCAAACTTTAA
GAAGCGTAGGGTATATTCTAAAAAACAATGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

85.135

99.107

0.844
  ciaR Streptococcus pneumoniae D39

84.685

99.107

0.839
  ciaR Streptococcus pneumoniae R6

84.685

99.107

0.839
  ciaR Streptococcus pneumoniae TIGR4

84.685

99.107

0.839
  ciaR Streptococcus pneumoniae Rx1

84.685

99.107

0.839
  covR Lactococcus lactis subsp. lactis strain DGCC12653

39.111

100

0.393
  vicR Streptococcus mutans UA159

35.897

100

0.375
  micA Streptococcus pneumoniae Cp1015

35.47

100

0.371
  covR Streptococcus salivarius strain HSISS4

36.283

100

0.366

Multiple sequence alignment