Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   GP482_RS05995 Genome accession   NZ_CP046875
Coordinates   1227116..1227706 (-) Length   196 a.a.
NCBI ID   WP_039696423.1    Uniprot ID   A0A091BS49
Organism   Streptococcus ruminicola strain CNU_77-61     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1218326..1229711 1227116..1227706 within 0


Gene organization within MGE regions


Location: 1218326..1229711
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GP482_RS05940 (GP482_05940) ricT 1218326..1219126 (-) 801 WP_158914357.1 regulatory iron-sulfur-containing complex subunit RicT -
  GP482_RS05945 (GP482_05945) - 1219123..1219998 (-) 876 WP_158914359.1 DNA polymerase III subunit delta' -
  GP482_RS05950 (GP482_05950) tmk 1220017..1220643 (-) 627 WP_074564243.1 dTMP kinase -
  GP482_RS05955 (GP482_05955) - 1220733..1221392 (-) 660 WP_157629288.1 CBS domain-containing protein -
  GP482_RS05960 (GP482_05960) - 1221527..1222237 (-) 711 WP_039696428.1 ABC transporter ATP-binding protein -
  GP482_RS05965 (GP482_05965) - 1222237..1223001 (-) 765 WP_039696427.1 ABC transporter ATP-binding protein -
  GP482_RS05970 (GP482_05970) - 1223001..1223954 (-) 954 WP_158914361.1 branched-chain amino acid ABC transporter permease -
  GP482_RS05975 (GP482_05975) - 1223958..1224842 (-) 885 WP_074564247.1 branched-chain amino acid ABC transporter permease -
  GP482_RS05980 (GP482_05980) - 1224900..1226078 (-) 1179 WP_158914363.1 ABC transporter substrate-binding protein -
  GP482_RS05985 (GP482_05985) - 1226190..1226441 (-) 252 WP_020917301.1 YlbG family protein -
  GP482_RS05990 (GP482_05990) - 1226434..1226874 (-) 441 WP_158914365.1 YlbF family regulator -
  GP482_RS05995 (GP482_05995) clpP 1227116..1227706 (-) 591 WP_039696423.1 ATP-dependent Clp protease proteolytic subunit Regulator
  GP482_RS06000 (GP482_06000) - 1227835..1228728 (-) 894 WP_039696422.1 DMT family transporter -
  GP482_RS06005 (GP482_06005) - 1228842..1229711 (+) 870 WP_074626285.1 LysR family transcriptional regulator -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 21510.45 Da        Isoelectric Point: 4.3383

>NTDB_id=409126 GP482_RS05995 WP_039696423.1 1227116..1227706(-) (clpP) [Streptococcus ruminicola strain CNU_77-61]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKSDVQTIVMGMAASMGTIIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQSDMAIAAEHLLKTRQNLEQILADNSGQ
SLEKVHADAERDNWMSAQETLEYGFIDEIMVNNELN

Nucleotide


Download         Length: 591 bp        

>NTDB_id=409126 GP482_RS05995 WP_039696423.1 1227116..1227706(-) (clpP) [Streptococcus ruminicola strain CNU_77-61]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGCGGTGAACGCTCATATGATATTTACTCACGTCTTTTGAAAGATCGTAT
CATTATGCTGACTGGACCAGTTGAAGACAATATGGCAAATTCTATTATTGCTCAACTATTGTTCCTTGATGCACAAGATA
ATACAAAAGATATTTACCTTTATGTTAATACACCTGGTGGATCAGTTTCAGCTGGTCTTGCTATTGTAGATACAATGAAC
TTCATTAAATCAGATGTTCAAACTATCGTTATGGGTATGGCAGCATCAATGGGAACAATCATTGCTTCATCAGGTACAAA
AGGTAAACGATTCATGTTGCCAAACGCTGAATATATGATTCACCAACCAATGGGTGGTACTGGTGGCGGTACTCAACAAA
GCGATATGGCTATTGCTGCTGAACACCTTTTGAAAACACGTCAAAACTTGGAACAAATTTTGGCTGACAACTCAGGTCAA
AGTTTGGAAAAAGTTCACGCTGATGCTGAACGTGATAACTGGATGAGCGCTCAAGAAACTCTTGAATATGGCTTCATCGA
TGAAATCATGGTTAACAACGAATTGAACTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(11-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A091BS49

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Streptococcus thermophilus LMG 18311

95.897

99.49

0.954
  clpP Streptococcus thermophilus LMD-9

95.897

99.49

0.954
  clpP Streptococcus pneumoniae Rx1

93.367

100

0.934
  clpP Streptococcus pneumoniae D39

93.367

100

0.934
  clpP Streptococcus pneumoniae R6

93.367

100

0.934
  clpP Streptococcus pneumoniae TIGR4

93.367

100

0.934
  clpP Streptococcus pyogenes JRS4

89.286

100

0.893
  clpP Streptococcus pyogenes MGAS315

89.286

100

0.893
  clpP Streptococcus mutans UA159

88.265

100

0.883
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

87.755

100

0.878
  clpP Lactococcus lactis subsp. cremoris KW2

87.245

100

0.872
  clpP Bacillus subtilis subsp. subtilis str. 168

58.247

98.98

0.577
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.421

96.939

0.566

Multiple sequence alignment