Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   SSUD12_RS00355 Genome accession   NC_017621
Coordinates   58692..59591 (+) Length   299 a.a.
NCBI ID   WP_014637279.1    Uniprot ID   -
Organism   Streptococcus suis D12     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 53692..64591
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSUD12_RS00335 (SSUD12_0051) - 53985..55697 (+) 1713 WP_014637275.1 ABC transporter ATP-binding protein -
  SSUD12_RS11655 (SSUD12_0052) - 55798..55971 (+) 174 WP_014637276.1 hypothetical protein -
  SSUD12_RS00340 (SSUD12_0053) ruvB 56215..57216 (+) 1002 WP_014637277.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  SSUD12_RS00345 (SSUD12_0054) - 57216..57962 (+) 747 Protein_51 GNAT family N-acetyltransferase -
  SSUD12_RS00350 (SSUD12_0056) - 57964..58587 (+) 624 WP_014637278.1 HAD-IA family hydrolase -
  SSUD12_RS00355 (SSUD12_0057) comR 58692..59591 (+) 900 WP_014637279.1 helix-turn-helix domain-containing protein Regulator
  SSUD12_RS00360 (SSUD12_0058) - 59944..61146 (-) 1203 WP_014637280.1 IS110 family transposase -
  SSUD12_RS00365 (SSUD12_0059) - 61423..62643 (+) 1221 WP_014637281.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  SSUD12_RS00375 (SSUD12_0061) - 62834..64357 (+) 1524 WP_014637282.1 Heme/copper-type cytochrome/quinol oxidase subunit 1 -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35233.01 Da        Isoelectric Point: 4.4737

>NTDB_id=40827 SSUD12_RS00355 WP_014637279.1 58692..59591(+) (comR) [Streptococcus suis D12]
MNDKEFGQRVRQLRETASLTREQFCDDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEELVEKRDAIMTEIYDDYYDDLPEEEKIAIDSIQSRIDTLESGTAGFGKEILEDYFEQIFRKQKYEVND
LLIIRLQLEYVRLSSSDSEIFGQFLKIIEYLHGQIDIINSSDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQST
QDFQKKPIVSVLKWKYALFVDKDRDEAEKHYLDAVLFAKLIENRELEQKIEEDWRVDNQ

Nucleotide


Download         Length: 900 bp        

>NTDB_id=40827 SSUD12_RS00355 WP_014637279.1 58692..59591(+) (comR) [Streptococcus suis D12]
ATGAACGATAAGGAATTTGGACAACGTGTACGTCAACTTCGAGAAACCGCTAGTCTGACACGTGAACAGTTTTGCGATGA
CGAACTTGAGCTCTCCGTCCGCCAATTAACCCGTATCGAAGCAGGTACTTCTAAGCCGACTTTTTCAAAAATCCAATATA
TCGCAACCCGCTTAGGCATGGGGCTCTATGAGCTTATGCCTGATTATGTATCCTTGCCAGAAAGATACTCCAAGCTGAAA
TTTGATGTCCTCCGTACACCGACTTATGGTAATGAGGAATTAGTTGAAAAACGTGATGCTATCATGACGGAAATCTATGA
TGATTACTACGACGACTTGCCTGAGGAGGAGAAAATAGCGATTGATTCCATTCAATCCCGAATTGATACCTTAGAGTCAG
GGACAGCAGGCTTTGGAAAAGAGATACTGGAAGATTACTTTGAACAAATTTTCCGAAAACAAAAGTACGAAGTGAATGAT
TTGCTGATTATTAGGCTCCAGCTTGAATACGTTAGATTGTCCAGTAGTGACTCAGAAATATTTGGACAGTTTTTGAAAAT
TATAGAATATTTACATGGACAAATTGATATTATCAATTCAAGTGATTTATTTGTTCTAAGAGATACATTGTTATCTTGTG
TAAACATTTTGGGAAGTAAAAAATATTACGAACCAATACCAAAGATATTTGACAGTGTAGATAAGATTATACAGTCGACA
CAAGATTTTCAGAAAAAGCCCATTGTTAGTGTATTAAAATGGAAATATGCACTTTTTGTGGATAAGGATCGGGATGAGGC
TGAAAAGCATTATCTAGATGCGGTGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAACAAAAGATTGAAGAAGATT
GGAGAGTTGACAATCAATAA

Domains

Predicted by InterProScan.

Helix-turn-helix domain (HTH_31)

(5-60)

ComR tetratricopeptide (ComR_TPR)

(73-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

93.98

100

0.94
  comR Streptococcus suis 05ZYH33

93.98

100

0.94
  comR Streptococcus suis D9

59.801

100

0.602
  comR Streptococcus mutans UA159

45.151

100

0.452
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

37.801

97.324

0.368
  comR Streptococcus pyogenes MGAS315

37.037

99.331

0.368

Multiple sequence alignment