Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   GPX87_RS03960 Genome accession   NZ_CP046815
Coordinates   849638..850864 (+) Length   408 a.a.
NCBI ID   WP_078926031.1    Uniprot ID   A0A1T4PAP4
Organism   Vibrio cincinnatiensis strain 1398-82     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 844638..855864
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPX87_RS03935 fldB 845146..845664 (+) 519 WP_078926035.1 flavodoxin FldB -
  GPX87_RS03940 ampD 845671..846216 (-) 546 WP_078926149.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  GPX87_RS03945 nadC 846414..847304 (+) 891 WP_078926034.1 carboxylating nicotinate-nucleotide diphosphorylase -
  GPX87_RS03950 - 847501..847926 (+) 426 WP_078926033.1 pilin -
  GPX87_RS03955 pilB 847929..849617 (+) 1689 WP_078926032.1 type IV-A pilus assembly ATPase PilB Machinery gene
  GPX87_RS03960 pilC 849638..850864 (+) 1227 WP_078926031.1 type II secretion system F family protein Machinery gene
  GPX87_RS03965 pilD 850905..851771 (+) 867 WP_078926030.1 A24 family peptidase Machinery gene
  GPX87_RS03970 coaE 851777..852391 (+) 615 WP_078926029.1 dephospho-CoA kinase -
  GPX87_RS03975 zapD 852417..853157 (+) 741 WP_078926028.1 cell division protein ZapD -
  GPX87_RS03980 yacG 853215..853412 (+) 198 WP_078926027.1 DNA gyrase inhibitor YacG -
  GPX87_RS03985 parC 853477..855750 (-) 2274 WP_078926026.1 DNA topoisomerase IV subunit A -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44839.06 Da        Isoelectric Point: 10.3780

>NTDB_id=408258 GPX87_RS03960 WP_078926031.1 849638..850864(+) (pilC) [Vibrio cincinnatiensis strain 1398-82]
MHSSKVYELKNYRWKGINSSGKKVAGQLLALSELEVRDKLKEQHIQIKKIKKGGVSLLTRLTHRVKAKDITLLTRQLSTM
LTTGVPIVQALKLVGDNHRKAEMKSILAQITKSVEAGTPISKAMRTASSHFDPLYVDLIQTGEQSGNLAEVFERLATYRE
KSEQLRAKVVKALIYPSMVILVALGVSYLMLTMVIPEFESMFQGFGAELPWFTQQVLKLSHAAQAYSLGAILLISSLFLA
LKTARKKSFQVRLKTSRLGLKSPIIGGVLAKAAIAKFSRTLATSFAAGIPILASLKTTAKTAGNVHFETAIDQVHRDTAS
GMPMYIAMRNTEAFPEMVLQMVMIGEESGKLDDMLNKIATIYEFEVDNTVDNLGKILEPLIIVFLGVVVGGLVVAMYLPI
FNLMSVLG

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=408258 GPX87_RS03960 WP_078926031.1 849638..850864(+) (pilC) [Vibrio cincinnatiensis strain 1398-82]
ATGCATTCATCTAAAGTTTATGAACTGAAAAATTACCGTTGGAAAGGCATCAATAGTTCTGGGAAAAAAGTGGCTGGGCA
GTTACTCGCACTCAGTGAACTGGAAGTACGCGATAAACTCAAAGAGCAGCATATTCAGATCAAGAAAATAAAAAAAGGGG
GTGTTTCACTCCTCACCCGCTTAACTCACCGAGTCAAAGCGAAAGATATCACCCTACTTACCCGCCAATTATCGACCATG
TTAACCACGGGGGTTCCCATTGTTCAAGCACTCAAATTGGTCGGAGATAATCACCGTAAAGCAGAAATGAAATCGATTTT
GGCTCAAATTACTAAAAGTGTCGAAGCCGGCACTCCGATATCAAAAGCAATGCGTACCGCCAGTAGTCACTTTGATCCCC
TTTATGTCGACTTGATTCAAACAGGGGAGCAATCTGGAAATTTAGCCGAGGTCTTTGAACGCCTTGCTACCTACCGAGAA
AAAAGTGAACAGTTGCGCGCTAAAGTCGTCAAAGCGCTTATCTATCCGAGTATGGTTATTTTAGTTGCGTTGGGCGTTTC
CTACTTGATGCTAACCATGGTGATTCCTGAATTTGAAAGTATGTTCCAAGGTTTTGGCGCAGAGCTACCTTGGTTTACCC
AACAAGTTCTTAAACTCTCCCATGCTGCGCAAGCTTATAGTTTAGGGGCTATATTGCTGATCAGCAGCTTGTTTCTGGCC
CTGAAAACTGCTCGTAAAAAATCCTTTCAAGTCCGCCTTAAAACCAGCCGCTTAGGCTTAAAATCTCCGATTATTGGCGG
TGTCTTAGCAAAAGCTGCCATTGCCAAGTTTAGCCGTACCCTTGCGACCAGCTTTGCGGCGGGTATCCCTATTCTTGCCA
GTTTAAAAACCACCGCCAAAACTGCGGGTAATGTGCATTTTGAAACCGCGATTGATCAAGTACACCGAGATACCGCATCG
GGAATGCCAATGTACATTGCCATGCGCAATACAGAAGCCTTTCCCGAAATGGTGCTACAAATGGTCATGATTGGAGAAGA
GTCGGGAAAACTGGATGATATGTTGAATAAAATTGCGACCATTTACGAATTTGAAGTGGATAATACCGTGGATAATTTAG
GAAAAATCCTAGAGCCGTTGATTATCGTCTTCCTAGGAGTGGTGGTAGGAGGATTAGTGGTGGCGATGTATCTTCCCATC
TTTAACTTAATGAGTGTATTAGGTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(277-399)

Type II secretion system (T2SS), protein F (T2SSF)

(74-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1T4PAP4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio cholerae strain A1552

86.275

100

0.863
  pilC Vibrio campbellii strain DS40M4

73.067

98.284

0.718
  pilC Acinetobacter baumannii D1279779

41.912

100

0.419
  pilC Pseudomonas stutzeri DSM 10701

42.145

98.284

0.414
  pilC Acinetobacter baylyi ADP1

41.176

100

0.412
  pilC Legionella pneumophila strain ERS1305867

41.439

98.775

0.409
  pilG Neisseria meningitidis 44/76-A

40.541

99.755

0.404
  pilG Neisseria gonorrhoeae MS11

39.552

98.529

0.39

Multiple sequence alignment