Detailed information NTG0040650

Bioinformatically predicted

Overview

• Name: comGD
• Type: Machinery gene
• Locus tag: SSU12_RS00795
• Genome accession: NC_017619
• Coordinates: 122139..122546 (+)
• Length: 135 a.a.
• NCBI ID: WP_011921721.1
• Uniprot ID: A0A0H3MT39
• Organism: Streptococcus suis SS12
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 117139..127546

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSU12_RS00770 (SSU12_0123)	-	118547..118912 (+)	366	WP_002936568.1	DUF1033 family protein	-
SSU12_RS00775 (SSU12_0124)	-	118947..119890 (-)	944	Protein_115	S66 peptidase family protein	-
SSU12_RS00780 (SSU12_0126)	comGA	119976..120926 (+)	951	WP_011921718.1	competence type IV pilus ATPase ComGA	Machinery gene
SSU12_RS00785 (SSU12_0127)	comGB	120838..121875 (+)	1038	WP_011921719.1	competence type IV pilus assembly protein ComGB	Machinery gene
SSU12_RS00790 (SSU12_0128)	comGC	121877..122158 (+)	282	WP_011921720.1	competence type IV pilus major pilin ComGC	Machinery gene
SSU12_RS00795 (SSU12_0129)	comGD	122139..122546 (+)	408	WP_011921721.1	competence type IV pilus minor pilin ComGD	Machinery gene
SSU12_RS00800 (SSU12_0130)	comGE	122518..122811 (+)	294	WP_011921722.1	competence type IV pilus minor pilin ComGE	Machinery gene
SSU12_RS00805 (SSU12_0131)	comGF/cglF	122798..123232 (+)	435	WP_011922561.1	competence type IV pilus minor pilin ComGF	Machinery gene
SSU12_RS00810 (SSU12_0132)	comGG	123210..123620 (+)	411	WP_011921724.1	competence type IV pilus minor pilin ComGG	Machinery gene
SSU12_RS00815 (SSU12_0133)	comGH	123677..124630 (+)	954	WP_011922562.1	class I SAM-dependent methyltransferase	Machinery gene
SSU12_RS00820 (SSU12_0134)	-	124680..125867 (+)	1188	WP_012775422.1	acetate kinase	-
SSU12_RS00825 (SSU12_0136)	-	126182..126733 (+)	552	WP_012774908.1	folate family ECF transporter S component	-

Sequence

Protein

• Length: 135 a.a.
• Molecular weight: 15367.59 Da
• Isoelectric Point: 8.3926

>NTDB_id=40650 SSU12_RS00795 WP_011921721.1 122139..122546(+) (comGD) [Streptococcus suis SS12]
MLRRKNKAFTLFESLLTLLVVSFLAVSLSGTVQTVFRSVQEEIFLWEFEAIYKDSQKLAASSHKKVNLAIGGQEVTNGYQ
AVEVPRNVEVLEEKTIQFEEDGGNSSLTKIRFHLSQKIVTYQLYIGSGRYKKTEE

Nucleotide

• Length: 408 bp

>NTDB_id=40650 SSU12_RS00795 WP_011921721.1 122139..122546(+) (comGD) [Streptococcus suis SS12]
ATGCTACGGCGAAAAAATAAGGCTTTTACCCTGTTTGAAAGCCTGCTGACCTTGTTGGTTGTCAGTTTTTTAGCTGTTTC
CTTATCAGGAACAGTACAAACGGTCTTTCGGTCTGTTCAGGAAGAAATTTTTCTCTGGGAATTTGAGGCCATCTATAAAG
ACAGTCAGAAATTAGCAGCCAGTTCCCACAAAAAAGTGAACCTTGCTATCGGTGGACAGGAGGTTACAAATGGTTATCAG
GCTGTAGAGGTGCCCAGAAACGTAGAGGTCTTAGAGGAGAAAACTATTCAGTTTGAAGAAGATGGTGGAAATTCTTCTCT
GACCAAGATTCGTTTTCACCTTAGTCAAAAAATAGTCACGTATCAATTATATATAGGGAGTGGTCGCTATAAGAAAACAG
AAGAATAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A0H3MT39

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGD	Streptococcus gordonii str. Challis substr. CH1	48.031	94.074	0.452
comGD	Streptococcus mutans UA140	46.512	95.556	0.444
comGD	Streptococcus mutans UA159	46.512	95.556	0.444
comGD/cglD	Streptococcus pneumoniae TIGR4	44.961	95.556	0.43
comGD/cglD	Streptococcus pneumoniae R6	44.961	95.556	0.43
comGD/cglD	Streptococcus pneumoniae Rx1	44.961	95.556	0.43
comGD/cglD	Streptococcus pneumoniae D39	44.961	95.556	0.43
comGD/cglD	Streptococcus mitis NCTC 12261	44.186	95.556	0.422
comGD/cglD	Streptococcus mitis SK321	43.411	95.556	0.415
comGD	Lactococcus lactis subsp. cremoris KW2	39.062	94.815	0.37