Detailed information NTG0406275

Bioinformatically predicted

Overview

• Name: comE/comE2
• Type: Regulator
• Locus tag: GPA00_RS02025
• Genome accession: NZ_CP046629
• Coordinates: 403532..404260 (-)
• Length: 242 a.a.
• NCBI ID: WP_033153377.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain CNU G6
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 398532..409260

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GPA00_RS01995 (GPA00_01995)	-	398866..399807 (-)	942	WP_024343528.1	3'-5' exoribonuclease YhaM family protein	-
GPA00_RS02000 (GPA00_02000)	rmuC	399797..401011 (-)	1215	WP_371851905.1	DNA recombination protein RmuC	-
GPA00_RS02005 (GPA00_02005)	-	401074..401706 (-)	633	WP_024343527.1	thiamine diphosphokinase	-
GPA00_RS02010 (GPA00_02010)	rpe	401699..402361 (-)	663	WP_024343526.1	ribulose-phosphate 3-epimerase	-
GPA00_RS02015 (GPA00_02015)	rsgA	402368..403240 (-)	873	WP_027968346.1	ribosome small subunit-dependent GTPase A	-
GPA00_RS02025 (GPA00_02025)	comE/comE2	403532..404260 (-)	729	WP_033153377.1	LytR/AlgR family response regulator transcription factor	Regulator
GPA00_RS02030 (GPA00_02030)	comD/comD3	404880..405893 (-)	1014	WP_232524224.1	sensor histidine kinase	Regulator
GPA00_RS02035 (GPA00_02035)	comD/comD3	406266..407639 (-)	1374	WP_157327331.1	GHKL domain-containing protein	Regulator
GPA00_RS02040 (GPA00_02040)	-	408003..408296 (-)	294	WP_157327332.1	bacteriocin immunity protein	-
GPA00_RS02045 (GPA00_02045)	-	408324..408629 (-)	306	WP_157327334.1	bacteriocin immunity protein	-
GPA00_RS02050 (GPA00_02050)	-	408642..408791 (-)	150	WP_157327336.1	bacteriocin	-
GPA00_RS02055 (GPA00_02055)	comC/comC1	409053..409205 (+)	153	WP_157327338.1	hypothetical protein	Regulator

Sequence

Protein

• Length: 242 a.a.
• Molecular weight: 28297.51 Da
• Isoelectric Point: 6.4962

>NTDB_id=406275 GPA00_RS02025 WP_033153377.1 403532..404260(-) (comE/comE2) [Streptococcus equinus strain CNU G6]
MIDIYVLEDNVNQQFRIERMIDELLDENQWDYRHFEIFSEPSHFPNFVEESCPQIFFLDIDINGDNKKGIEVAKKIREKS
RTATIVFVTTHSEFMLLTYRAQVSALDFIDKSDEDSSIKINLKNCLRKVIENQALTMPQEFFVFENNKATIRIPMDEILY
FETAESHRLKLVTKSGQRNFYGSIKEVMAANQTFFRSHKSYLINLDNVVCLDKKNSLVHFVGGQSCLVSKKYIKELKLKI
GV

Nucleotide

• Length: 729 bp

>NTDB_id=406275 GPA00_RS02025 WP_033153377.1 403532..404260(-) (comE/comE2) [Streptococcus equinus strain CNU G6]
ATGATTGACATCTATGTATTGGAGGACAATGTAAATCAGCAATTTCGGATTGAAAGGATGATTGATGAACTACTCGATGA
AAATCAGTGGGACTATCGTCATTTTGAAATATTTAGTGAGCCGTCTCATTTTCCAAATTTTGTTGAGGAATCTTGCCCAC
AAATTTTTTTCTTAGATATTGATATCAATGGTGATAATAAAAAGGGAATTGAAGTCGCTAAGAAAATTAGGGAGAAATCT
AGAACAGCTACGATTGTTTTTGTTACGACGCATTCTGAGTTTATGTTGTTGACTTACCGAGCACAGGTTAGTGCACTTGA
TTTTATTGATAAGTCAGATGAAGACAGTTCGATAAAAATTAATTTAAAAAATTGTTTGCGAAAGGTCATCGAAAATCAGG
CTCTTACGATGCCACAGGAATTTTTTGTATTTGAAAATAATAAAGCTACTATTCGTATTCCGATGGATGAAATTCTTTAT
TTTGAAACAGCTGAAAGTCATCGACTGAAGTTGGTTACAAAGTCGGGACAACGTAATTTTTATGGTTCAATCAAAGAAGT
AATGGCTGCTAATCAGACCTTTTTTAGAAGCCACAAATCGTATCTGATTAATCTTGATAATGTTGTGTGCTTAGATAAAA
AGAATAGTTTGGTGCATTTTGTCGGTGGTCAATCTTGCCTTGTTTCAAAGAAATACATTAAAGAATTAAAGTTGAAAATA
GGGGTTTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (6-115)

• LytTr DNA-binding domain (LytTR) (149-239)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/comE2	Streptococcus equinus JB1	74.167	99.174	0.736
comE/comE1	Streptococcus equinus JB1	44.118	98.347	0.434
comE/blpR	Streptococcus mutans UA159	40.164	100	0.405
comE/comE2	Streptococcus gordonii strain NCTC7865	38.367	100	0.388
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	38.367	100	0.388