Detailed information NTG0406270

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: GPA00_RS00995
• Genome accession: NZ_CP046629
• Coordinates: 193626..194216 (-)
• Length: 196 a.a.
• NCBI ID: WP_021142943.1
• Uniprot ID: A0A1G9KV94
• Organism: Streptococcus equinus strain CNU G6
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 188626..199216

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GPA00_RS00965 (GPA00_00965)	-	188902..189666 (-)	765	WP_021142936.1	ABC transporter ATP-binding protein	-
GPA00_RS00970 (GPA00_00970)	-	189666..190619 (-)	954	WP_021142937.1	branched-chain amino acid ABC transporter permease	-
GPA00_RS00975 (GPA00_00975)	-	190623..191507 (-)	885	WP_157327167.1	branched-chain amino acid ABC transporter permease	-
GPA00_RS00980 (GPA00_00980)	-	191564..192742 (-)	1179	WP_024343674.1	ABC transporter substrate-binding protein	-
GPA00_RS00985 (GPA00_00985)	-	192839..193090 (-)	252	WP_021142941.1	DUF2129 domain-containing protein	-
GPA00_RS00990 (GPA00_00990)	-	193083..193520 (-)	438	WP_004232950.1	YlbF family regulator	-
GPA00_RS00995 (GPA00_00995)	clpP	193626..194216 (-)	591	WP_021142943.1	ATP-dependent Clp protease proteolytic subunit	Regulator
GPA00_RS01000 (GPA00_01000)	-	194293..195186 (-)	894	WP_157327169.1	DMT family transporter	-
GPA00_RS01005 (GPA00_01005)	-	195300..196169 (+)	870	WP_074628405.1	LysR family transcriptional regulator	-
GPA00_RS01010 (GPA00_01010)	upp	196233..196862 (-)	630	WP_021142946.1	uracil phosphoribosyltransferase	-
GPA00_RS01015 (GPA00_01015)	-	197028..198191 (-)	1164	WP_157327171.1	MalY/PatB family protein	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21538.50 Da
• Isoelectric Point: 4.3383

>NTDB_id=406270 GPA00_RS00995 WP_021142943.1 193626..194216(-) (clpP) [Streptococcus equinus strain CNU G6]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKSDVQTIVMGMAASMGTIIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRQNLEQILADNSGQ
TLEKVHADAERDNWMSAQETLEYGFIDEIMVNNELN

Nucleotide

• Length: 591 bp

>NTDB_id=406270 GPA00_RS00995 WP_021142943.1 193626..194216(-) (clpP) [Streptococcus equinus strain CNU G6]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGCGGCGAACGCTCATATGATATTTACTCACGTCTTTTGAAAGATCGTAT
CATTATGCTGACTGGACCAGTTGAAGATAATATGGCAAATTCTATTATTGCTCAACTATTGTTCCTTGATGCACAAGATA
ATACAAAAGATATCTACCTTTATGTTAATACACCTGGAGGATCAGTTTCAGCTGGTCTTGCTATCGTCGATACAATGAAC
TTCATCAAATCTGACGTTCAAACAATCGTTATGGGTATGGCTGCATCAATGGGTACAATCATTGCATCATCAGGTACAAA
AGGTAAACGATTCATGTTGCCAAATGCTGAATACATGATTCACCAACCAATGGGTGGTACTGGTGGCGGTACTCAACAAA
CTGATATGGCAATCGCTGCTGAACACCTTTTGAAAACACGTCAAAACTTGGAACAAATTTTGGCTGATAATTCAGGTCAA
ACATTGGAAAAAGTTCACGCAGATGCTGAACGTGATAACTGGATGAGCGCTCAAGAAACTCTTGAATATGGCTTTATCGA
TGAAATCATGGTCAACAACGAATTGAACTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A1G9KV94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus thermophilus LMG 18311	96.41	99.49	0.959
clpP	Streptococcus thermophilus LMD-9	96.41	99.49	0.959
clpP	Streptococcus pneumoniae Rx1	93.367	100	0.934
clpP	Streptococcus pneumoniae D39	93.367	100	0.934
clpP	Streptococcus pneumoniae R6	93.367	100	0.934
clpP	Streptococcus pneumoniae TIGR4	93.367	100	0.934
clpP	Streptococcus pyogenes JRS4	90.306	100	0.903
clpP	Streptococcus pyogenes MGAS315	90.306	100	0.903
clpP	Streptococcus mutans UA159	88.265	100	0.883
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	87.755	100	0.878
clpP	Lactococcus lactis subsp. cremoris KW2	87.245	100	0.872
clpP	Bacillus subtilis subsp. subtilis str. 168	58.763	98.98	0.582
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.947	96.939	0.571