Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   GO596_RS07690 Genome accession   NZ_CP046628
Coordinates   1538494..1539168 (+) Length   224 a.a.
NCBI ID   WP_024344055.1    Uniprot ID   A0A239RAE4
Organism   Streptococcus equinus strain CNU 77-23     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1533494..1544168
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GO596_RS07675 (GO596_07675) pstB 1534145..1534903 (+) 759 WP_074450517.1 phosphate ABC transporter ATP-binding protein PstB -
  GO596_RS07680 (GO596_07680) phoU 1534935..1535588 (+) 654 WP_024344053.1 phosphate signaling complex protein PhoU -
  GO596_RS07685 (GO596_07685) - 1535797..1538340 (+) 2544 WP_157339526.1 M1 family metallopeptidase -
  GO596_RS07690 (GO596_07690) ciaR 1538494..1539168 (+) 675 WP_024344055.1 response regulator transcription factor Regulator
  GO596_RS07695 (GO596_07695) ciaH 1539158..1540483 (+) 1326 WP_141348012.1 sensor histidine kinase Regulator
  GO596_RS07700 (GO596_07700) rpsT 1540566..1540817 (-) 252 WP_004231769.1 30S ribosomal protein S20 -
  GO596_RS07705 (GO596_07705) coaA 1540893..1541813 (-) 921 WP_094140583.1 type I pantothenate kinase -
  GO596_RS07710 (GO596_07710) - 1541927..1542517 (+) 591 WP_024344058.1 class I SAM-dependent methyltransferase -
  GO596_RS07715 (GO596_07715) deoC 1543020..1543685 (+) 666 WP_021142326.1 deoxyribose-phosphate aldolase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25372.99 Da        Isoelectric Point: 4.3773

>NTDB_id=406257 GO596_RS07690 WP_024344055.1 1538494..1539168(+) (ciaR) [Streptococcus equinus strain CNU 77-23]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGAEGLYEAESGVYDLILLDLMLPEKDGFQVLKELREKGISTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNNNTLSYHELTADTSTNTTTVNGEKVELLGKEFDLLVY
FLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTSFANNLQTLRSVGYILKDAE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=406257 GO596_RS07690 WP_024344055.1 1538494..1539168(+) (ciaR) [Streptococcus equinus strain CNU 77-23]
ATGATTAAAATTTTATTAGTAGAAGACGATTTGAGCTTGTCAAATTCAATTTTTGATTTTTTGGATGATTTTGCGGATGT
CATGCAGGTTTTTGATGGCGCAGAAGGTTTATATGAAGCAGAAAGTGGTGTTTATGACCTTATTTTGCTTGATTTGATGT
TGCCAGAAAAAGATGGTTTCCAAGTTCTTAAAGAATTACGTGAAAAAGGCATTTCAACACCTGTTTTGATTATGACAGCT
AAAGAAAGTCTTGATGACAAAGGACATGGATTCGAATTAGGTGCTGATGATTACCTAACAAAACCATTTTATCTTGAAGA
ACTTAAGATGCGTATTCAAGCTCTTTTAAAACGTTCAGGTAAATTTAATAACAATACTTTGTCATATCATGAATTAACTG
CGGATACTTCAACAAATACAACAACCGTTAACGGTGAAAAAGTTGAATTACTAGGTAAAGAGTTTGATTTGTTAGTATAC
TTTTTGCAAAACCAAAATGTCATTTTGCCAAAATCACAAATTTTTGACCGTATTTGGGGCTTTGACAGTGATACAACAAT
TTCAGTTGTTGAAGTATATGTTTCAAAAATTCGTAAAAAACTCAAAGGTACTAGCTTTGCCAATAATCTTCAAACACTAC
GTAGTGTAGGTTACATATTGAAAGATGCTGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A239RAE4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

91.928

99.554

0.915
  ciaR Streptococcus pneumoniae Rx1

87.5

100

0.875
  ciaR Streptococcus pneumoniae D39

87.5

100

0.875
  ciaR Streptococcus pneumoniae R6

87.5

100

0.875
  ciaR Streptococcus pneumoniae TIGR4

87.5

100

0.875
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.767

100

0.393
  micA Streptococcus pneumoniae Cp1015

34.764

100

0.362
  vicR Streptococcus mutans UA159

34.764

100

0.362

Multiple sequence alignment