Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   GO995_RS06960 Genome accession   NZ_CP046624
Coordinates   1396347..1397057 (-) Length   236 a.a.
NCBI ID   WP_039696509.1    Uniprot ID   A0A6G8HYC0
Organism   Streptococcus ruminicola strain CNU_G3     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1391347..1402057
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GO995_RS06945 (GO995_06945) rnc 1393284..1393970 (-) 687 WP_020917219.1 ribonuclease III -
  GO995_RS06950 (GO995_06950) vicX 1394192..1395001 (-) 810 WP_074602529.1 MBL fold metallo-hydrolase Regulator
  GO995_RS06955 (GO995_06955) vicK 1395002..1396354 (-) 1353 WP_157629241.1 cell wall metabolism sensor histidine kinase VicK Regulator
  GO995_RS06960 (GO995_06960) vicR 1396347..1397057 (-) 711 WP_039696509.1 response regulator YycF Regulator
  GO995_RS06965 (GO995_06965) - 1397369..1398133 (+) 765 WP_039696508.1 amino acid ABC transporter ATP-binding protein -
  GO995_RS06970 (GO995_06970) - 1398144..1398956 (+) 813 WP_157629242.1 transporter substrate-binding domain-containing protein -
  GO995_RS06975 (GO995_06975) - 1398972..1399679 (+) 708 WP_039696506.1 amino acid ABC transporter permease -
  GO995_RS06980 (GO995_06980) - 1399692..1400339 (+) 648 WP_157629243.1 amino acid ABC transporter permease -
  GO995_RS06985 (GO995_06985) - 1400377..1400985 (-) 609 WP_006532767.1 TVP38/TMEM64 family protein -
  GO995_RS06990 (GO995_06990) - 1401198..1401500 (-) 303 WP_157629244.1 hypothetical protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27121.90 Da        Isoelectric Point: 4.7040

>NTDB_id=406179 GO995_RS06960 WP_039696509.1 1396347..1397057(-) (vicR) [Streptococcus ruminicola strain CNU_G3]
MKKILIVDDEKPISDIIKFNLTKEGYETVTAFDGREAIAKFEEENPDLIILDLMLPELDGLEVAKEVRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIESAVAEENASSSNSEITIGDLKILPDAFVAQKRGEDIE
LTHREFELLHHLATHMGQVMTREYLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKSYE

Nucleotide


Download         Length: 711 bp        

>NTDB_id=406179 GO995_RS06960 WP_039696509.1 1396347..1397057(-) (vicR) [Streptococcus ruminicola strain CNU_G3]
ATGAAAAAAATTCTTATTGTTGATGATGAAAAACCAATTTCAGATATTATTAAATTTAACTTAACTAAAGAAGGTTATGA
AACTGTTACGGCTTTTGATGGTCGTGAAGCAATTGCTAAATTTGAAGAAGAAAATCCTGATTTGATTATCTTGGATTTGA
TGTTGCCAGAATTGGATGGACTTGAAGTTGCAAAAGAAGTTCGTAAAACAAGTCATATTCCGATTATTATGCTTTCTGCT
AAAGATAGCGAGTTCGATAAAGTTATCGGTCTTGAAATCGGTGCAGATGACTACGTTACAAAACCTTTCTCAAATCGTGA
ATTGTTAGCACGTGTCAAAGCACACCTTCGTCGTACTGAGAACATCGAATCAGCCGTCGCTGAGGAAAATGCTTCTTCAT
CAAATTCTGAAATTACCATCGGCGATTTGAAGATTTTGCCTGATGCCTTTGTTGCCCAAAAACGTGGCGAAGACATTGAA
TTAACACACCGTGAATTTGAATTACTTCATCACTTAGCTACCCACATGGGACAAGTGATGACGCGTGAATACCTTTTGGA
GACTGTTTGGGGTTATGACTATTTTGGTGATGTCCGTACAGTTGACGTAACAATCCGTCGTTTACGTGAAAAAATCGAAG
ACACTCCGAGCCGTCCAGAATATATTTTGACACGTCGTGGTGTTGGATATTACATGAAGTCTTATGAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6G8HYC0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.678

100

0.907
  micA Streptococcus pneumoniae Cp1015

78.205

99.153

0.775
  covR Streptococcus salivarius strain HSISS4

46.983

98.305

0.462
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.69

98.305

0.449
  scnR Streptococcus mutans UA159

36.441

100

0.364

Multiple sequence alignment