Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   GO995_RS06955 Genome accession   NZ_CP046624
Coordinates   1395002..1396354 (-) Length   450 a.a.
NCBI ID   WP_157629241.1    Uniprot ID   -
Organism   Streptococcus ruminicola strain CNU_G3     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1390002..1401354
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GO995_RS06945 (GO995_06945) rnc 1393284..1393970 (-) 687 WP_020917219.1 ribonuclease III -
  GO995_RS06950 (GO995_06950) vicX 1394192..1395001 (-) 810 WP_074602529.1 MBL fold metallo-hydrolase Regulator
  GO995_RS06955 (GO995_06955) vicK 1395002..1396354 (-) 1353 WP_157629241.1 cell wall metabolism sensor histidine kinase VicK Regulator
  GO995_RS06960 (GO995_06960) vicR 1396347..1397057 (-) 711 WP_039696509.1 response regulator YycF Regulator
  GO995_RS06965 (GO995_06965) - 1397369..1398133 (+) 765 WP_039696508.1 amino acid ABC transporter ATP-binding protein -
  GO995_RS06970 (GO995_06970) - 1398144..1398956 (+) 813 WP_157629242.1 transporter substrate-binding domain-containing protein -
  GO995_RS06975 (GO995_06975) - 1398972..1399679 (+) 708 WP_039696506.1 amino acid ABC transporter permease -
  GO995_RS06980 (GO995_06980) - 1399692..1400339 (+) 648 WP_157629243.1 amino acid ABC transporter permease -
  GO995_RS06985 (GO995_06985) - 1400377..1400985 (-) 609 WP_006532767.1 TVP38/TMEM64 family protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51364.32 Da        Isoelectric Point: 4.7359

>NTDB_id=406178 GO995_RS06955 WP_157629241.1 1395002..1396354(-) (vicK) [Streptococcus ruminicola strain CNU_G3]
MNDTMVQNQYLFEQAILFLLAFVAVYFIHLAIRDYRTSVNIRRLSGKVRELITGKYTEDIIIEKDRDLAELAGQLNDLST
VFRLAQENLAQEKNRLASILSYMTDGVLATDRSGNITMINQTAQKQLNLEREEALGMNIVDILGDDSDYSYHDLVSKTPE
IVLNRRDETGEFITLRIRFALNRRDSGFISGLIAVLHDTTEQEKEDRERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMIRMISDLLNLSRIDNQTVQLEVEMTNFTAFMTSILNRFDQIKSQHTVAGKQYEIVRDYPIKS
IWVEIDPDKMTQVLDNILNNAIKYSPDGGKITVSMKTTETQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGSG
LGLAIAKEIVKQHKGFIWAQSTYGKGSTFTIVLPYEKDSDIYDEWEDDED

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=406178 GO995_RS06955 WP_157629241.1 1395002..1396354(-) (vicK) [Streptococcus ruminicola strain CNU_G3]
ATGAATGATACAATGGTACAGAATCAGTATCTGTTTGAGCAGGCAATCTTGTTTTTGCTCGCTTTTGTCGCTGTTTATTT
TATTCATTTAGCGATAAGAGATTATCGAACTTCAGTTAATATTCGTCGTTTGAGTGGTAAGGTTCGTGAGCTTATCACTG
GTAAATACACTGAAGACATCATTATTGAAAAAGATAGAGATTTAGCTGAACTTGCTGGTCAGTTAAATGACTTGTCAACG
GTTTTTCGTTTGGCTCAGGAAAACCTTGCGCAGGAAAAAAATCGTTTGGCTAGTATTTTGTCTTATATGACTGACGGTGT
CTTGGCTACTGACCGTTCTGGAAATATCACCATGATTAACCAGACCGCTCAAAAGCAACTAAATCTTGAGCGTGAAGAAG
CTCTTGGGATGAATATCGTTGACATTCTTGGTGATGATAGCGATTATTCTTACCATGATTTGGTGTCTAAGACGCCAGAA
ATTGTGCTTAATCGTCGCGATGAGACGGGAGAATTTATCACTTTGCGCATTCGTTTCGCCTTAAATCGTAGAGATAGTGG
TTTTATTTCTGGGCTGATTGCTGTCTTGCATGATACGACAGAGCAAGAAAAAGAAGACCGTGAACGTCGCTTGTTCGTTT
CTAACGTTAGTCATGAATTGCGTACGCCACTGACTTCGGTTAAATCTTATCTTGAGGCACTGGATGAAGGGGCTCTGAAA
GAAGATATTGCACCAAGTTTCATTAAAGTTTCTTTGGATGAAACCAACCGTATGATTCGCATGATTTCTGATTTGCTTAA
TCTGTCTCGAATCGACAATCAAACGGTGCAATTAGAAGTTGAAATGACGAACTTCACAGCCTTTATGACGTCTATTTTGA
ATCGTTTTGACCAGATTAAGAGCCAACACACGGTTGCTGGCAAGCAATACGAAATTGTCAGAGACTATCCGATCAAGTCA
ATCTGGGTTGAAATTGACCCAGATAAGATGACCCAGGTCTTGGATAATATCCTAAATAATGCCATTAAGTATTCACCAGA
CGGTGGTAAAATCACTGTTAGCATGAAGACAACTGAAACTCAGTTGATTATTTCGATTTCTGATGAAGGACTTGGTATTC
CGAAGAAAGACTTGCCGTTAATCTTTGACCGTTTCTACCGTGTTGATAAGGCTAGAAGTCGTGCCCAAGGTGGTTCAGGG
CTTGGACTTGCCATTGCTAAAGAAATTGTCAAACAACATAAAGGATTTATTTGGGCTCAAAGTACCTATGGTAAGGGCTC
AACATTTACAATTGTTCTTCCGTATGAGAAGGATTCTGATATTTATGATGAATGGGAGGATGACGAGGACTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-189)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

76.867

92.222

0.709
  micB Streptococcus pneumoniae Cp1015

64.465

97.556

0.629

Multiple sequence alignment