Detailed information    

insolico Bioinformatically predicted

Overview

Name   comC/comC1   Type   Regulator
Locus tag   GOM47_RS09615 Genome accession   NZ_CP046524
Coordinates   1940785..1940913 (-) Length   42 a.a.
NCBI ID   WP_081102474.1    Uniprot ID   A0A139M7G0
Organism   Streptococcus oralis strain SOT     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context

Location: 1935785..1945913
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM47_RS09590 (GOM47_09590) - 1937904..1938446 (+) 543 WP_235080667.1 TetR/AcrR family transcriptional regulator -
  GOM47_RS09605 (GOM47_09605) comE 1938687..1939439 (-) 753 WP_084948177.1 competence system response regulator transcription factor ComE Regulator
  GOM47_RS09610 (GOM47_09610) comD 1939436..1940773 (-) 1338 WP_235080668.1 competence system sensor histidine kinase ComD Regulator
  GOM47_RS09615 (GOM47_09615) comC/comC1 1940785..1940913 (-) 129 WP_081102474.1 competence-stimulating peptide ComC Regulator
  GOM47_RS09625 (GOM47_09625) rlmH 1941194..1941673 (-) 480 WP_235080669.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  GOM47_RS09630 (GOM47_09630) htrA 1941857..1943047 (+) 1191 WP_235080670.1 S1C family serine protease Regulator
  GOM47_RS09635 (GOM47_09635) spo0J 1943105..1943863 (+) 759 WP_235080671.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 42 a.a.        Molecular weight: 5021.92 Da        Isoelectric Point: 10.4867

>NTDB_id=405025 GOM47_RS09615 WP_081102474.1 1940785..1940913(-) (comC/comC1) [Streptococcus oralis strain SOT]
MKNTVKLEQFKEVTEAELQEIRGGDKRGLMDLFKQIPIFRRK

Nucleotide


Download         Length: 129 bp        

>NTDB_id=405025 GOM47_RS09615 WP_081102474.1 1940785..1940913(-) (comC/comC1) [Streptococcus oralis strain SOT]
ATGAAAAACACAGTTAAATTGGAACAATTTAAAGAAGTAACAGAGGCAGAATTGCAGGAGATTCGGGGTGGAGATAAAAG
AGGATTAATGGATCTTTTCAAGCAAATTCCTATTTTTAGGAGAAAATAA

Domains

Predicted by InterproScan.

COMC family (ComC)

(1-25)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A139M7G0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC/comC1 Streptococcus pneumoniae Rx1

50

100

0.5
  comC/comC1 Streptococcus pneumoniae R6

50

100

0.5
  comC/comC1 Streptococcus pneumoniae G54

50

100

0.5
  comC/comC1 Streptococcus pneumoniae D39

50

100

0.5
  comC Streptococcus mitis SK321

66.667

64.286

0.429
  comC Streptococcus mitis NCTC 12261

42.857

100

0.429
  comC/comC2 Streptococcus pneumoniae A66

62.963

64.286

0.405
  comC/comC2 Streptococcus pneumoniae TIGR4

62.963

64.286

0.405

Multiple sequence alignment