Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD   Type   Regulator
Locus tag   GOM47_RS09610 Genome accession   NZ_CP046524
Coordinates   1939436..1940773 (-) Length   445 a.a.
NCBI ID   WP_235080668.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOT     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1934436..1945773
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM47_RS09585 (GOM47_09585) - 1935121..1937775 (-) 2655 WP_235080666.1 YhgE/Pip domain-containing protein -
  GOM47_RS09590 (GOM47_09590) - 1937904..1938446 (+) 543 WP_235080667.1 TetR/AcrR family transcriptional regulator -
  GOM47_RS09605 (GOM47_09605) comE 1938687..1939439 (-) 753 WP_084948177.1 competence system response regulator transcription factor ComE Regulator
  GOM47_RS09610 (GOM47_09610) comD 1939436..1940773 (-) 1338 WP_235080668.1 competence system sensor histidine kinase ComD Regulator
  GOM47_RS09615 (GOM47_09615) comC/comC1 1940785..1940913 (-) 129 WP_081102474.1 competence-stimulating peptide ComC Regulator
  GOM47_RS09625 (GOM47_09625) rlmH 1941194..1941673 (-) 480 WP_235080669.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  GOM47_RS09630 (GOM47_09630) htrA 1941857..1943047 (+) 1191 WP_235080670.1 S1C family serine protease Regulator
  GOM47_RS09635 (GOM47_09635) spo0J 1943105..1943863 (+) 759 WP_235080671.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 52201.26 Da        Isoelectric Point: 6.1196

>NTDB_id=405024 GOM47_RS09610 WP_235080668.1 1939436..1940773(-) (comD) [Streptococcus oralis strain SOT]
MDIMVGILDAFLTCVIISKIYSRICEISKKERYIFGFIFFIFQLIYAFIFSFIDSDKLILILHYTLKNFYPILFYCYFKF
IKKYDSSKNIFLSLIFSLLYQSAHTFFSVTISSITGDLLVEQHERLFFFIINLISYLVIDKIITYFNLELKYFDKDYLYP
FLKKVIVAFFTLHIVLFISDIVSTFPHLNSFGSILAAIIFICMLLCFFAMNSHKVQVEKEIALKQKKFEQKHLQTYTDEI
VELYNEIRGFRHDYAGMLVSMQMAIDSGDLQEIDRIYKEVLVKANQKLRSEKYTYFDLNSIEDSALRSVIAQSIVYARNN
DVEFTLEVKDIITRLSMDLLDLVRIMSILLNNAVEGATDSYLKQMEVAVIKMDFETVIVIQNSCKITMTPSEDLFALGFS
TKGKNRGLGLNNVKEILDKYDNIILETEMEDNTFRQIIRFKREFE

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=405024 GOM47_RS09610 WP_235080668.1 1939436..1940773(-) (comD) [Streptococcus oralis strain SOT]
ATGGATATTATGGTAGGAATATTAGATGCATTCTTAACTTGTGTTATAATCAGTAAAATTTATAGTCGAATTTGTGAAAT
TTCTAAAAAAGAAAGATATATTTTTGGTTTTATATTCTTTATATTTCAATTAATTTATGCTTTTATATTCTCTTTTATAG
ATTCTGATAAATTAATACTGATTTTACATTATACTTTAAAGAATTTTTATCCAATTCTATTCTATTGCTATTTTAAATTT
ATTAAAAAGTATGATTCCTCAAAAAATATATTTTTAAGTTTAATATTTTCACTATTGTATCAAAGTGCTCATACTTTTTT
TTCCGTTACTATATCATCTATTACAGGTGACTTACTTGTAGAACAACATGAAAGATTATTCTTTTTCATAATTAATTTAA
TTTCCTATCTTGTAATAGACAAAATTATTACCTATTTTAATCTAGAACTTAAATATTTTGACAAAGATTATCTCTATCCT
TTTTTAAAAAAAGTTATAGTTGCTTTCTTCACTTTACATATTGTACTGTTTATTTCAGATATTGTTAGTACTTTTCCTCA
TTTAAATAGCTTTGGGAGTATTTTAGCAGCAATTATTTTTATATGTATGTTATTGTGCTTCTTTGCAATGAACTCTCATA
AAGTTCAAGTTGAAAAAGAGATTGCTCTAAAACAAAAGAAATTTGAACAAAAGCATTTACAGACTTATACTGATGAAATT
GTAGAGTTGTATAATGAAATTCGAGGTTTTCGTCATGACTATGCTGGGATGCTTGTCAGCATGCAAATGGCAATTGACAG
TGGAGATTTACAAGAAATTGACAGAATTTACAAGGAAGTCTTAGTAAAAGCAAATCAAAAATTGAGGTCAGAAAAGTATA
CTTACTTTGATCTAAACAGTATAGAGGACTCAGCTTTACGAAGTGTGATTGCTCAATCAATTGTATATGCACGAAATAAT
GATGTAGAGTTTACATTGGAAGTAAAAGATATCATTACTAGATTGTCAATGGATTTACTTGATCTTGTTCGCATCATGAG
TATTCTCTTAAACAATGCTGTTGAAGGTGCTACGGATAGTTACTTGAAACAAATGGAAGTTGCAGTTATTAAAATGGATT
TTGAAACAGTTATAGTCATCCAGAATTCATGTAAAATCACTATGACGCCTTCAGAGGACTTATTTGCTTTAGGATTCTCT
ACTAAGGGAAAAAATAGAGGTCTAGGACTTAATAATGTTAAAGAGATTTTAGATAAGTATGACAACATTATTTTAGAAAC
AGAGATGGAAGACAACACATTTAGACAAATTATTAGATTTAAGAGGGAATTCGAATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(338-438)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD Streptococcus mitis NCTC 12261

69.799

100

0.701
  comD/comD2 Streptococcus pneumoniae TIGR4

68.75

100

0.692
  comD Streptococcus mitis SK321

70.208

97.303

0.683
  comD/comD1 Streptococcus pneumoniae D39

69.816

97.528

0.681
  comD/comD1 Streptococcus pneumoniae Rx1

69.816

97.528

0.681
  comD/comD1 Streptococcus pneumoniae R6

69.816

97.528

0.681
  comD/comD2 Streptococcus gordonii strain NCTC7865

51.175

86.067

0.44
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

50.781

86.292

0.438

Multiple sequence alignment