Detailed information NTG0405026

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: GOM47_RS09630
• Genome accession: NZ_CP046524
• Coordinates: 1941857..1943047 (+)
• Length: 396 a.a.
• NCBI ID: WP_235080670.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain SOT
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1936857..1948047

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GOM47_RS09590 (GOM47_09590)	-	1937904..1938446 (+)	543	WP_235080667.1	TetR/AcrR family transcriptional regulator	-
GOM47_RS09605 (GOM47_09605)	comE	1938687..1939439 (-)	753	WP_084948177.1	competence system response regulator transcription factor ComE	Regulator
GOM47_RS09610 (GOM47_09610)	comD	1939436..1940773 (-)	1338	WP_235080668.1	competence system sensor histidine kinase ComD	Regulator
GOM47_RS09615 (GOM47_09615)	comC/comC1	1940785..1940913 (-)	129	WP_081102474.1	competence-stimulating peptide ComC	Regulator
GOM47_RS09625 (GOM47_09625)	rlmH	1941194..1941673 (-)	480	WP_235080669.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
GOM47_RS09630 (GOM47_09630)	htrA	1941857..1943047 (+)	1191	WP_235080670.1	S1C family serine protease	Regulator
GOM47_RS09635 (GOM47_09635)	spo0J	1943105..1943863 (+)	759	WP_235080671.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 396 a.a.
• Molecular weight: 41788.69 Da
• Isoelectric Point: 6.5078

>NTDB_id=405026 GOM47_RS09630 WP_235080670.1 1941857..1943047(+) (htrA) [Streptococcus oralis strain SOT]
MKHLQTFYKKGVTFLIIILIGFLSGALGSFVTLQLYQKQGSQATNNTTNTVTQTSYKNENATTQAVNKVKDAVVSVITYS
ANRQNSVFGNDETDTDTDSQQVASEGSGVIYKKNGKDAYLVTNTHVIKGASKVDIRLADGTKVPGEIVGSDTFSDIAVVK
ISSEKVTTVAEFGDSSKLNVGETAIAIGSPLGSEYANTVTQGIISSLNRNVSLKSQDGQAISTKAIQTDTAINPGNSGGP
LVNIQGQVIGITSSKIASNGGTSVEGLGFAIPSNDAQNIIKQLESDGKVTRPALGIQMVNLTNIGASDLRKLNIPSSVTS
GVVVKSVQSNMPASGHLEKYDVITKVDDKEISSSTDLQSALYNHSIGDTIKITYYRNGKEDTTTVKLDKSTSDLES

Nucleotide

• Length: 1191 bp

>NTDB_id=405026 GOM47_RS09630 WP_235080670.1 1941857..1943047(+) (htrA) [Streptococcus oralis strain SOT]
ATGAAACACTTACAAACATTTTACAAAAAAGGAGTTACCTTTCTTATCATCATTCTGATAGGATTTTTGAGTGGTGCTCT
GGGAAGTTTTGTGACACTGCAACTTTATCAGAAGCAAGGAAGTCAAGCAACAAATAACACTACAAACACTGTTACTCAGA
CTTCCTATAAAAATGAAAATGCAACTACTCAGGCCGTTAATAAGGTAAAAGATGCCGTTGTGTCGGTTATCACTTACTCA
GCAAATCGACAAAATAGCGTTTTTGGAAATGACGAAACAGATACGGATACCGACTCTCAACAAGTAGCAAGTGAAGGTTC
TGGTGTTATTTACAAAAAGAATGGGAAAGATGCCTACCTTGTGACAAATACCCACGTTATTAAAGGAGCTTCAAAAGTTG
ATATCCGTTTAGCAGACGGTACAAAAGTTCCTGGTGAAATTGTCGGTTCTGATACGTTCTCTGATATTGCTGTCGTAAAA
ATTTCTTCAGAAAAAGTCACAACCGTAGCAGAATTTGGAGATTCTAGCAAACTAAATGTTGGTGAGACTGCAATCGCAAT
TGGTAGTCCTCTAGGATCCGAATATGCCAATACAGTTACCCAAGGAATCATTTCAAGTCTCAATCGAAATGTCTCTCTAA
AATCTCAAGATGGTCAAGCGATTTCTACAAAAGCTATTCAGACAGATACGGCCATTAACCCTGGTAACTCTGGTGGTCCA
CTGGTAAATATTCAAGGACAAGTCATCGGTATTACATCAAGTAAAATTGCAAGTAATGGTGGAACCTCTGTCGAAGGTCT
TGGTTTTGCAATCCCATCAAATGATGCTCAAAATATTATTAAACAGCTTGAAAGTGATGGTAAAGTGACTCGCCCTGCTC
TTGGAATTCAAATGGTTAATTTAACTAATATCGGAGCTAGTGATCTTAGAAAACTCAATATTCCAAGTAGCGTAACTTCT
GGTGTAGTGGTAAAATCTGTTCAAAGTAATATGCCTGCATCTGGTCACCTTGAAAAATACGACGTTATTACCAAAGTTGA
CGACAAGGAGATTTCTTCGTCAACAGATTTACAGAGTGCTCTTTACAACCATTCTATCGGAGACACCATTAAAATCACCT
ACTATCGAAATGGGAAAGAGGATACTACGACTGTTAAACTAGATAAAAGTACAAGTGATTTAGAATCTTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (292-387)

• Trypsin-like peptidase domain (Trypsin_2) (106-251)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mitis NCTC 12261	84.848	100	0.848
htrA	Streptococcus pneumoniae Rx1	83.586	100	0.836
htrA	Streptococcus pneumoniae D39	83.586	100	0.836
htrA	Streptococcus pneumoniae R6	83.586	100	0.836
htrA	Streptococcus pneumoniae TIGR4	83.586	100	0.836
htrA	Streptococcus gordonii str. Challis substr. CH1	65.829	100	0.662
htrA	Streptococcus mutans UA159	54.637	100	0.551