Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   GOM46_RS00170 Genome accession   NZ_CP046525
Coordinates   37024..38322 (+) Length   432 a.a.
NCBI ID   WP_235083607.1    Uniprot ID   -
Organism   Streptococcus infantis strain SO     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 32024..43322
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM46_RS00140 (GOM46_00140) - 32043..33212 (+) 1170 WP_235083603.1 pyridoxal phosphate-dependent aminotransferase -
  GOM46_RS00145 (GOM46_00145) recO 33209..33979 (+) 771 WP_235083604.1 DNA repair protein RecO -
  GOM46_RS00150 (GOM46_00150) plsX 33976..34968 (+) 993 WP_006150504.1 phosphate acyltransferase PlsX -
  GOM46_RS00155 (GOM46_00155) - 34970..35206 (+) 237 WP_235083605.1 acyl carrier protein -
  GOM46_RS00160 (GOM46_00160) cysK 35260..36186 (-) 927 WP_006150537.1 cysteine synthase A -
  GOM46_RS00165 (GOM46_00165) - 36333..36968 (-) 636 WP_235083606.1 YigZ family protein -
  GOM46_RS00170 (GOM46_00170) comFA/cflA 37024..38322 (+) 1299 WP_235083607.1 DEAD/DEAH box helicase Machinery gene
  GOM46_RS00175 (GOM46_00175) comFC/cflB 38319..38981 (+) 663 WP_006150533.1 ComF family protein Machinery gene
  GOM46_RS00180 (GOM46_00180) hpf 39061..39609 (+) 549 WP_006150510.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  GOM46_RS00185 (GOM46_00185) - 39826..41034 (+) 1209 WP_235083608.1 acyl-CoA dehydrogenase family protein -
  GOM46_RS00190 (GOM46_00190) - 41138..41986 (+) 849 WP_006150532.1 3-hydroxybutyryl-CoA dehydrogenase -
  GOM46_RS00195 (GOM46_00195) - 42005..43183 (+) 1179 WP_235083609.1 acetyl-CoA C-acetyltransferase -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49552.85 Da        Isoelectric Point: 8.8047

>NTDB_id=405029 GOM46_RS00170 WP_235083607.1 37024..38322(+) (comFA/cflA) [Streptococcus infantis strain SO]
MKINPNYLGRLFTEDELSMEEHQLAVKLPSMRKEKGKLVCQRCDSVIQEEWLLPIDAYYCRECLLMKRVRSDQGLYYFPQ
EEFPKQEVLKWQGQLTPFQEKVSKGLLKAVESQQPTLVHAVTGAGKTEMIYEVVAKVINDGGAVCLASPRIDVCLELYKR
LQNDFACKIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNKMLYKAVKNCVKENGLSIFLTATST
DELDKKVRLGELKRLSLPRRFHGNPLIIPKPVWLSELDNYLDKHRLPPKLKSYIEKQRKSGYPLLIFASEIKKGEKLKEI
LQLQFPNEKIGFVSSVTEDRLEQVQAFRDRELTILISTTILERGVTFPCVDVMVVEANHRLFTKSSLIQIGGRVGRSMDR
PTGDLIFFHNGLNRSIKNAIKEIKLMNKEAGL

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=405029 GOM46_RS00170 WP_235083607.1 37024..38322(+) (comFA/cflA) [Streptococcus infantis strain SO]
ATGAAAATAAACCCAAATTATCTAGGTCGACTTTTTACTGAAGATGAATTAAGTATGGAAGAACATCAGTTAGCAGTGAA
ACTCCCAAGTATGCGAAAAGAGAAGGGAAAACTAGTTTGTCAACGATGTGATAGTGTGATTCAAGAAGAATGGTTATTGC
CCATTGATGCATACTACTGTCGAGAATGTCTGTTGATGAAGCGAGTTAGGAGTGATCAAGGTTTATATTATTTCCCTCAG
GAAGAATTTCCAAAACAAGAGGTTCTTAAATGGCAGGGACAATTGACTCCATTTCAAGAGAAAGTATCAAAAGGATTACT
TAAAGCTGTAGAAAGTCAGCAGCCAACTTTAGTTCATGCCGTGACTGGCGCTGGGAAAACAGAGATGATTTATGAAGTTG
TGGCAAAAGTCATTAATGATGGTGGGGCAGTTTGTTTAGCGAGCCCCCGGATAGATGTTTGTTTGGAGTTATATAAACGA
CTACAAAATGATTTTGCCTGTAAAATCGCGTTGTTACATGGGGAATCTGAACCATATTTTCGGACACCTCTAGTTGTTGC
AACGACTCACCAGTTATTAAAATTCTATCAAGCTTTTGATTTACTAATAGTTGATGAAGTTGATGCTTTTCCCTATGTTG
ACAACAAGATGCTTTACAAAGCTGTAAAGAATTGTGTAAAGGAAAACGGACTCAGCATTTTCCTTACAGCTACCTCTACA
GATGAATTGGATAAAAAGGTTCGCTTAGGAGAGTTGAAAAGGTTAAGTTTACCAAGGCGGTTTCATGGTAACCCCTTAAT
AATTCCCAAACCAGTCTGGCTATCTGAATTGGACAATTACTTAGACAAACATCGTCTACCACCCAAATTAAAAAGCTATA
TAGAAAAACAACGAAAATCAGGCTATCCATTACTCATTTTCGCTTCAGAGATTAAAAAAGGAGAGAAGTTAAAGGAAATC
TTGCAGCTGCAGTTTCCAAATGAGAAAATAGGCTTCGTATCGTCTGTTACAGAAGATCGATTAGAACAAGTTCAAGCATT
TAGAGATAGAGAATTAACCATCTTGATAAGTACAACAATATTGGAACGTGGAGTTACCTTTCCATGTGTAGACGTAATGG
TTGTCGAAGCAAATCATCGCCTCTTTACAAAATCGAGTTTAATTCAAATTGGAGGACGAGTTGGACGCAGCATGGATAGA
CCAACTGGAGATTTAATTTTCTTTCATAATGGATTAAATCGTTCGATTAAAAATGCCATAAAAGAAATTAAGTTGATGAA
TAAGGAGGCAGGTTTATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(291-396)

Type III restriction enzyme, res subunit (ResIII)

(94-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae R6

87.269

100

0.873
  comFA/cflA Streptococcus pneumoniae Rx1

87.269

100

0.873
  comFA/cflA Streptococcus pneumoniae D39

87.269

100

0.873
  comFA/cflA Streptococcus mitis NCTC 12261

87.037

100

0.87
  comFA/cflA Streptococcus pneumoniae TIGR4

87.037

100

0.87
  comFA/cflA Streptococcus mitis SK321

86.111

100

0.861
  comFA Lactococcus lactis subsp. cremoris KW2

50.856

94.676

0.481
  comFA Latilactobacillus sakei subsp. sakei 23K

38.303

100

0.387

Multiple sequence alignment