Detailed information NTG0404998

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: GOM47_RS06110
• Genome accession: NZ_CP046524
• Coordinates: 1199521..1200171 (-)
• Length: 216 a.a.
• NCBI ID: WP_235080192.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain SOT
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1194521..1205171

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GOM47_RS06085 (GOM47_06090)	-	1195464..1195844 (-)	381	WP_235080190.1	VOC family protein	-
GOM47_RS06090 (GOM47_06095)	rplT	1195903..1196262 (-)	360	WP_000124830.1	50S ribosomal protein L20	-
GOM47_RS06095 (GOM47_06100)	rpmI	1196314..1196514 (-)	201	WP_001125942.1	50S ribosomal protein L35	-
GOM47_RS06100 (GOM47_06105)	infC	1196547..1197077 (-)	531	WP_000848184.1	translation initiation factor IF-3	-
GOM47_RS06105 (GOM47_06110)	comEC/celB	1197297..1199537 (-)	2241	WP_235080191.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
GOM47_RS06110 (GOM47_06115)	comEA/celA/cilE	1199521..1200171 (-)	651	WP_235080192.1	helix-hairpin-helix domain-containing protein	Machinery gene
GOM47_RS06115 (GOM47_06120)	-	1200238..1200807 (-)	570	WP_235080193.1	GNAT family N-acetyltransferase	-
GOM47_RS06120 (GOM47_06125)	ald	1200986..1202098 (+)	1113	WP_235080194.1	alanine dehydrogenase	-
GOM47_RS06125 (GOM47_06130)	-	1202150..1203136 (-)	987	WP_000658168.1	PhoH family protein	-
GOM47_RS06130 (GOM47_06135)	-	1203217..1203432 (-)	216	WP_001232084.1	YozE family protein	-
GOM47_RS06135 (GOM47_06140)	-	1203456..1204034 (-)	579	WP_235080195.1	GrpB family protein	-
GOM47_RS06140 (GOM47_06145)	cvfB	1204046..1204900 (-)	855	WP_235080196.1	RNA-binding virulence regulatory protein CvfB	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23128.20 Da
• Isoelectric Point: 5.0659

>NTDB_id=404998 GOM47_RS06110 WP_235080192.1 1199521..1200171(-) (comEA/celA/cilE) [Streptococcus oralis strain SOT]
MEAIIEKIKEYKIIVICAGLGLALGGFFLLKPSTQTPVKETNLQAEVAAVSKDSSSEKEVNKEEKEESAEQDLITVDVKG
AVKSPGIYDLPVGSRVHDAVQKAGGLTDEADSKSLNLAQKVSDEALVYVPTKGEEAASQQVASGTTPSTSEDKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHRETNGKFKSVDELKKVSGIGAKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=404998 GOM47_RS06110 WP_235080192.1 1199521..1200171(-) (comEA/celA/cilE) [Streptococcus oralis strain SOT]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATTGTCATTTGTGCTGGTTTGGGTTTGGCCTTGGGCGGATT
TTTCCTACTAAAGCCATCTACACAAACACCTGTGAAAGAAACAAATTTGCAGGCTGAAGTCGCAGCTGTTTCAAAGGATT
CATCTTCTGAAAAAGAAGTGAACAAGGAAGAAAAGGAAGAGTCTGCTGAACAAGATCTAATAACAGTAGATGTCAAGGGT
GCTGTTAAATCGCCAGGGATTTATGATTTGCCAGTAGGAAGTCGAGTTCATGATGCCGTTCAGAAGGCAGGTGGCTTGAC
AGATGAGGCAGATAGCAAGTCGCTCAATCTCGCTCAGAAAGTCAGTGACGAGGCTCTTGTCTATGTTCCAACTAAGGGAG
AAGAAGCAGCTAGTCAGCAGGTTGCCTCTGGAACGACTCCTTCGACAAGTGAAGATAAGAAGGTCAACCTTAATAAAGCT
AGTCTGGAAGAACTAAAACAGGTCAAAGGCTTGGGAGGAAAACGAGCCCAGGATATTATCGATCATCGTGAGACAAATGG
CAAATTCAAGTCGGTAGATGAATTAAAGAAAGTTTCTGGTATTGGCGCTAAGACCATAGAAAAGCTAAAAGATTATGTCA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (76-126)

• Helix-hairpin-helix motif (HHH_3) (153-214)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	90.278	100	0.903
comEA/celA/cilE	Streptococcus mitis NCTC 12261	90.278	100	0.903
comEA/celA/cilE	Streptococcus pneumoniae Rx1	89.352	100	0.894
comEA/celA/cilE	Streptococcus pneumoniae D39	89.352	100	0.894
comEA/celA/cilE	Streptococcus pneumoniae R6	89.352	100	0.894
comEA/celA/cilE	Streptococcus mitis SK321	87.037	100	0.87
comEA	Lactococcus lactis subsp. cremoris KW2	42.731	100	0.449