Detailed information NTG0404997

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: GOM47_RS06105
• Genome accession: NZ_CP046524
• Coordinates: 1197297..1199537 (-)
• Length: 746 a.a.
• NCBI ID: WP_235080191.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain SOT
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1192297..1204537

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GOM47_RS06075 (GOM47_06080)	-	1193466..1194452 (-)	987	WP_235080189.1	dihydroorotate dehydrogenase	-
GOM47_RS06080 (GOM47_06085)	-	1194415..1195215 (-)	801	WP_042902385.1	dihydroorotate dehydrogenase electron transfer subunit	-
GOM47_RS06085 (GOM47_06090)	-	1195464..1195844 (-)	381	WP_235080190.1	VOC family protein	-
GOM47_RS06090 (GOM47_06095)	rplT	1195903..1196262 (-)	360	WP_000124830.1	50S ribosomal protein L20	-
GOM47_RS06095 (GOM47_06100)	rpmI	1196314..1196514 (-)	201	WP_001125942.1	50S ribosomal protein L35	-
GOM47_RS06100 (GOM47_06105)	infC	1196547..1197077 (-)	531	WP_000848184.1	translation initiation factor IF-3	-
GOM47_RS06105 (GOM47_06110)	comEC/celB	1197297..1199537 (-)	2241	WP_235080191.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
GOM47_RS06110 (GOM47_06115)	comEA/celA/cilE	1199521..1200171 (-)	651	WP_235080192.1	helix-hairpin-helix domain-containing protein	Machinery gene
GOM47_RS06115 (GOM47_06120)	-	1200238..1200807 (-)	570	WP_235080193.1	GNAT family N-acetyltransferase	-
GOM47_RS06120 (GOM47_06125)	ald	1200986..1202098 (+)	1113	WP_235080194.1	alanine dehydrogenase	-
GOM47_RS06125 (GOM47_06130)	-	1202150..1203136 (-)	987	WP_000658168.1	PhoH family protein	-
GOM47_RS06130 (GOM47_06135)	-	1203217..1203432 (-)	216	WP_001232084.1	YozE family protein	-
GOM47_RS06135 (GOM47_06140)	-	1203456..1204034 (-)	579	WP_235080195.1	GrpB family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84662.86 Da
• Isoelectric Point: 9.0412

>NTDB_id=404997 GOM47_RS06105 WP_235080191.1 1197297..1199537(-) (comEC/celB) [Streptococcus oralis strain SOT]
MSQWIKNSPIPLIYLSFLLLWLYYAIFGASYLALLGFVFLLVCLFFQFPWKSAGRVLAICGVFGFWFLFQTWQQTQASQN
LVDSVEKVRILPDTIKVNGDSLSFRGKAEGRTLQVYYKLQSEEEKELFQALTDLHEIELEGKPSEPEGQRNFGGFNYQAY
LKTQGIYQTLTIKSIQSMKQVSSWDIRENLSSLRRKAVVWIKMHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMEAFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFII
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVARESLVISLGILPILSFYFAEFQAWSILLTFVFSFLFDLVFLPLLSI
LFILSFAYPVTQFNLVFEWLENIIRLVSQLASRPLVFGQPNAWLLILLLVSLALVYDMRKNIKRLAGVSLFIVGLFFLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKVEASKKIEAWQEKVTTSNAQRTLIPYLKSRGVDKIDQLILTNTDK
EHVGDLLEVTKAFHIGEILVSKGSLTQKEFVAELEASKNKVRSVTAGEYFPIFGSYLELLSPRQIGDGDRDDSLVLYGKL
LDKHFLFTGNLKEKGEKDLLKQYPDLEVDVLKAGQHGAKTSSNSAFLEQLKPEFTLISVGKSNRAKLPHQETLTQLENIK
SKIYRTDQQGAIRFKGWNSWRIETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=404997 GOM47_RS06105 WP_235080191.1 1197297..1199537(-) (comEC/celB) [Streptococcus oralis strain SOT]
ATGTCACAGTGGATTAAGAATTCCCCAATTCCCCTAATCTATCTGAGTTTTCTATTGCTCTGGCTTTACTATGCAATTTT
TGGAGCGTCCTATCTCGCACTGCTAGGTTTTGTTTTTTTGCTTGTCTGTCTCTTTTTCCAATTTCCTTGGAAATCGGCCG
GTAGAGTTCTAGCGATTTGTGGAGTTTTTGGATTTTGGTTTTTGTTTCAAACTTGGCAACAGACACAAGCTAGTCAAAAC
CTAGTGGATTCTGTTGAGAAGGTACGGATTTTGCCTGACACTATTAAGGTCAATGGAGATAGTCTGTCCTTTCGGGGCAA
GGCTGAGGGCCGCACCCTCCAAGTTTACTATAAACTCCAGTCTGAGGAGGAGAAAGAGCTCTTTCAGGCCTTAACAGACC
TTCACGAGATAGAGCTAGAAGGAAAACCTTCAGAGCCTGAAGGTCAGAGGAATTTTGGTGGCTTTAACTATCAAGCATAT
CTAAAGACTCAAGGAATTTACCAAACTTTGACTATCAAGAGTATCCAGTCAATGAAACAGGTTAGCAGTTGGGATATAAG
AGAAAATCTGTCTAGTTTACGTCGAAAGGCTGTAGTTTGGATCAAGATGCACTTTCCAGATCCTATGCGCAACTATATGA
CAGGTCTTCTTTTAGGACATTTGGACACGGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTTGGAATTATCCATCTC
TTTGCCTTGTCTGGTATGCAGGTGGGCTTCTTTATGGAGGCCTTTAAGAAACTCCTCTTGCGATTGGGCTTGACTCAAGA
AAAGTTGAAGTGGCTAACCTATCCCTTTTCCCTTATCTATGCAGGTCTGACAGGATTTTCAGCTTCGGTCATTCGTAGTC
TCTTACAAAAGTTACTAGCCCAACATGGTGTTAAGGGCTTGGACAATTTTGCCTTAACAGTCCTTGTCCTCTTTATCATC
ATGCCCAACTTTTTCCTAACAGCAGGAGGAGTCTTGTCTTGCGCTTATGCTTTTATCTTGACCATGACAAGCAAAGAAGG
GGAGGGACTCAAGGCTGTTGCCAGAGAAAGTTTGGTCATTTCTTTGGGAATATTGCCCATTCTATCCTTTTATTTTGCAG
AATTTCAGGCTTGGTCTATCCTTTTGACCTTTGTATTTTCCTTTCTGTTTGATCTGGTCTTCTTGCCGCTTTTGTCCATC
TTATTCATTCTGTCTTTTGCTTACCCAGTCACTCAGTTTAACCTTGTCTTTGAGTGGTTGGAGAACATCATTCGCTTGGT
ATCGCAGCTGGCAAGCAGGCCTCTGGTCTTTGGTCAACCCAACGCATGGCTGCTGATTCTACTGTTAGTTTCATTAGCCT
TAGTCTATGACATGAGGAAAAACATCAAAAGACTAGCAGGAGTCAGTCTTTTTATCGTGGGGCTCTTTTTCTTGACCAAG
CACCCACTTGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGTGAAAGTATTTTCCTACGGGATGTAACTGGTAAAAC
TATTCTCATAGATGTTGGTGGTAAGGTAGAAGCTAGTAAGAAAATCGAGGCTTGGCAAGAAAAGGTGACAACCAGCAATG
CCCAGAGAACCTTGATTCCCTATCTTAAAAGTCGAGGAGTAGACAAGATTGACCAGCTGATTTTGACCAACACAGACAAG
GAACATGTTGGTGATTTACTGGAGGTGACCAAAGCTTTCCATATCGGGGAGATTTTAGTGTCAAAAGGAAGTTTGACACA
GAAGGAATTTGTAGCGGAACTAGAAGCAAGTAAAAACAAGGTACGTAGTGTGACAGCTGGGGAGTATTTCCCGATTTTTG
GCAGTTACTTAGAACTTCTATCTCCAAGGCAGATTGGAGATGGGGATCGTGATGATTCTCTGGTTCTTTATGGAAAACTT
TTGGATAAGCACTTTCTCTTCACAGGAAATTTGAAAGAGAAGGGAGAGAAGGATCTTCTAAAGCAATACCCTGACTTAGA
GGTGGATGTCCTGAAAGCAGGCCAACATGGTGCTAAAACATCATCCAATTCAGCTTTCCTAGAACAGCTCAAACCTGAGT
TCACTCTCATTTCAGTTGGAAAGAGCAATCGAGCAAAACTCCCTCATCAGGAAACCTTGACACAACTGGAAAATATCAAG
AGTAAGATTTACCGAACTGACCAGCAAGGGGCTATCCGCTTTAAAGGATGGAATAGTTGGAGAATTGAAACGGTTCGATA
A

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-632)

• Domain of unknown function (DUF4131) (DUF4131) (31-176)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	87.802	100	0.878
comEC/celB	Streptococcus mitis NCTC 12261	87.248	99.866	0.871
comEC/celB	Streptococcus pneumoniae TIGR4	86.059	100	0.861
comEC/celB	Streptococcus pneumoniae Rx1	85.523	100	0.855
comEC/celB	Streptococcus pneumoniae D39	85.523	100	0.855
comEC/celB	Streptococcus pneumoniae R6	85.523	100	0.855
comEC	Lactococcus lactis subsp. cremoris KW2	44.818	99.598	0.446