Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   GOM47_RS04860 Genome accession   NZ_CP046524
Coordinates   944683..945390 (+) Length   235 a.a.
NCBI ID   WP_235081242.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOT     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 939683..950390
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM47_RS04835 (GOM47_04835) - 939979..940650 (+) 672 WP_000151563.1 GTP pyrophosphokinase family protein -
  GOM47_RS04840 (GOM47_04840) - 940634..941452 (+) 819 WP_235081238.1 NAD kinase -
  GOM47_RS04845 (GOM47_04845) - 941449..942345 (+) 897 WP_235081239.1 RluA family pseudouridine synthase -
  GOM47_RS04850 (GOM47_04850) pta 942391..943365 (+) 975 WP_235081240.1 phosphate acetyltransferase -
  GOM47_RS04855 (GOM47_04855) mutY 943448..944626 (+) 1179 WP_235081241.1 A/G-specific adenine glycosylase -
  GOM47_RS04860 (GOM47_04860) micA 944683..945390 (+) 708 WP_235081242.1 response regulator YycF Regulator
  GOM47_RS04865 (GOM47_04865) micB 945383..946732 (+) 1350 WP_235081243.1 cell wall metabolism sensor histidine kinase VicK Regulator
  GOM47_RS04870 (GOM47_04870) vicX 946734..947543 (+) 810 WP_235081244.1 MBL fold metallo-hydrolase Regulator
  GOM47_RS04875 (GOM47_04875) - 947575..947922 (-) 348 WP_235081245.1 thioredoxin -
  GOM47_RS04880 (GOM47_04880) - 948033..949751 (-) 1719 WP_235081246.1 phospho-sugar mutase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26952.79 Da        Isoelectric Point: 4.6844

>NTDB_id=404989 GOM47_RS04860 WP_235081242.1 944683..945390(+) (micA) [Streptococcus oralis strain SOT]
MKKILVVDDEKPISDIIKFNMTKEGYEVVTAFNGREAIELFEAEKPDIIILDLMLPEIDGLEVAKAIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTDLASADSQESDEKKSQPLQIGDLEILPDAYVAKKYGEELEL
THREFELLYHLASHIGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRSND

Nucleotide


Download         Length: 708 bp        

>NTDB_id=404989 GOM47_RS04860 WP_235081242.1 944683..945390(+) (micA) [Streptococcus oralis strain SOT]
ATGAAAAAAATATTAGTTGTAGATGATGAGAAACCAATCTCAGATATTATTAAGTTCAATATGACCAAAGAAGGCTATGA
GGTTGTAACGGCCTTCAACGGTCGTGAGGCGATCGAGCTATTTGAAGCTGAGAAACCCGACATTATTATCCTAGACTTGA
TGCTACCTGAAATTGATGGTTTAGAAGTAGCCAAAGCCATTCGTAAGACGAGTAGTGTGCCTATTATTATGCTCTCAGCC
AAGGATAGTGAGTTTGACAAGGTTATCGGTTTAGAACTTGGGGCAGATGATTATGTGACCAAACCCTTCTCAAATCGTGA
GTTGCAAGCGCGTGTAAAGGCTTTACTCCGCCGTACAGACCTCGCTTCAGCTGATAGTCAAGAGTCTGATGAAAAGAAAT
CCCAACCCCTACAGATTGGCGATTTGGAAATTCTGCCGGACGCTTACGTAGCCAAAAAATATGGTGAGGAATTAGAGTTG
ACTCATCGTGAGTTTGAGCTCTTGTACCACTTGGCCTCTCATATTGGTCAAGTGATTACGCGTGAACACTTGCTTGAGAC
TGTTTGGGGCTATGATTATTTTGGTGATGTTCGTACAGTGGACGTGACCATCCGACGTTTGCGTGAAAAAATCGAAGACA
CTCCAAGCCGTCCAGAATACATCCTAACCCGTCGTGGTGTGGGTTATTATATGAGAAGTAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

90.171

99.574

0.898
  vicR Streptococcus mutans UA159

77.872

100

0.779
  covR Streptococcus salivarius strain HSISS4

43.59

99.574

0.434
  covR Lactococcus lactis subsp. lactis strain DGCC12653

42.857

98.298

0.421
  scnR Streptococcus mutans UA159

36.481

99.149

0.362

Multiple sequence alignment