Detailed information NTG0404990

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: GOM47_RS04865
• Genome accession: NZ_CP046524
• Coordinates: 945383..946732 (+)
• Length: 449 a.a.
• NCBI ID: WP_235081243.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain SOT
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 940383..951732

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GOM47_RS04840 (GOM47_04840)	-	940634..941452 (+)	819	WP_235081238.1	NAD kinase	-
GOM47_RS04845 (GOM47_04845)	-	941449..942345 (+)	897	WP_235081239.1	RluA family pseudouridine synthase	-
GOM47_RS04850 (GOM47_04850)	pta	942391..943365 (+)	975	WP_235081240.1	phosphate acetyltransferase	-
GOM47_RS04855 (GOM47_04855)	mutY	943448..944626 (+)	1179	WP_235081241.1	A/G-specific adenine glycosylase	-
GOM47_RS04860 (GOM47_04860)	micA	944683..945390 (+)	708	WP_235081242.1	response regulator YycF	Regulator
GOM47_RS04865 (GOM47_04865)	micB	945383..946732 (+)	1350	WP_235081243.1	cell wall metabolism sensor histidine kinase VicK	Regulator
GOM47_RS04870 (GOM47_04870)	vicX	946734..947543 (+)	810	WP_235081244.1	MBL fold metallo-hydrolase	Regulator
GOM47_RS04875 (GOM47_04875)	-	947575..947922 (-)	348	WP_235081245.1	thioredoxin	-
GOM47_RS04880 (GOM47_04880)	-	948033..949751 (-)	1719	WP_235081246.1	phospho-sugar mutase	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 51606.16 Da
• Isoelectric Point: 4.7599

>NTDB_id=404990 GOM47_RS04865 WP_235081243.1 945383..946732(+) (micB) [Streptococcus oralis strain SOT]
MIEAIKQSVLNRDFIFILILLGFILVVTLLLLENRRDNIRLKQINQKVKDLIVGDYSRVLDMQGSSEITNITNNLNDLSE
VIRLTQENLEQETKRLNSILSYMTDGVLATNRRGQITMINDMAKKQLGIVKEEALNKSILELLKIEDEYELRDLITQIPE
LMIDSQNANGEYLSLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALY
DPVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATTRLDVELINFTAFITFILNRFDKMRSQDEEKKYELVRDYPINSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDDQMILSISDQGLGIPKQDLPKIFDRFYRVDRARSRAQGGTGLG
LAIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED

Nucleotide

• Length: 1350 bp

>NTDB_id=404990 GOM47_RS04865 WP_235081243.1 945383..946732(+) (micB) [Streptococcus oralis strain SOT]
ATGATTGAAGCAATTAAACAAAGCGTTCTGAACAGAGATTTTATCTTTATTTTGATTTTGCTGGGCTTTATCTTGGTGGT
CACCTTGCTATTGCTAGAAAATCGCCGTGATAATATTCGGCTAAAGCAGATTAATCAAAAGGTCAAGGATTTGATTGTAG
GGGATTATTCTCGAGTTTTGGATATGCAAGGAAGCTCTGAAATCACTAACATCACCAATAACCTTAATGACTTGTCTGAG
GTCATTCGTCTAACGCAGGAAAATCTGGAGCAAGAAACAAAAAGGCTTAACAGTATTCTTTCTTATATGACAGATGGAGT
TCTTGCAACCAATCGCCGTGGTCAGATTACTATGATTAACGATATGGCCAAGAAACAGCTGGGTATCGTAAAAGAAGAAG
CATTGAACAAAAGCATCCTAGAATTGCTTAAGATAGAGGATGAATATGAACTGCGTGACCTCATTACACAGATTCCTGAA
TTGATGATTGATTCCCAAAATGCTAACGGAGAATATCTTAGTCTTCGTGTGCGTTTTGCACTCATTCGTCGTGAGTCTGG
ATTCATCTCTGGTTTGGTTGCCGTTTTGCACGATACGACTGAACAGGAGAAGGAAGAGCGTGAGCGGAGACTCTTTGTTT
CTAACGTGAGTCATGAGTTGAGAACTCCTTTGACCAGTGTTAAGTCCTATCTTGAAGCCTTGGACGAGGGAGCCTTGTAT
GATCCTGTTGCTCCTGATTTTATCAAGGTTTCGCTCGATGAAACCAACCGTATGATGCGGATGGTGACAGATCTTTTGCA
TCTCTCTCGTATTGATAATGCGACCACTCGGTTGGATGTGGAATTGATTAATTTTACAGCCTTCATCACCTTTATCCTCA
ACCGCTTTGATAAGATGAGGAGCCAGGATGAAGAGAAAAAATATGAGCTGGTTAGAGATTATCCTATCAATTCAGTTTGG
ATCGAGATTGACACCGATAAGATGACCCAGGTGATTGATAATATTCTCAACAATGCCATCAAGTACTCACCAGACGGTGG
AAAGATTACTGTCAGCATGAAAACAACAGATGACCAGATGATTTTATCTATCTCAGATCAGGGGTTAGGAATTCCAAAAC
AAGATTTGCCTAAAATTTTTGACCGTTTCTATCGTGTGGATCGTGCACGAAGCCGAGCTCAGGGTGGAACTGGTCTAGGT
CTGGCTATCGCAAAAGAAATCATCAAACAACACAATGGCTTTATATGGGCCAAAAGTGAATACGGCAAGGGCTCAACCTT
TACCATCGTGCTCCCTTATGATAAGGATGCCGTAAAAGAAGAAGTATGGGAGGATGAAGTAGAAGACTAG

Domains

Predicted by InterproScan.

• PAS fold (PAS) (95-198)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (324-434)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	89.294	97.773	0.873
vicK	Streptococcus mutans UA159	71.144	89.532	0.637