Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   GOM48_RS05415 Genome accession   NZ_CP046523
Coordinates   1071581..1072288 (-) Length   235 a.a.
NCBI ID   WP_235096360.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOD     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1066581..1077288
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM48_RS05395 (GOM48_05415) - 1067215..1068933 (+) 1719 WP_235096356.1 phospho-sugar mutase -
  GOM48_RS05400 (GOM48_05420) - 1069044..1069391 (+) 348 WP_235096357.1 thioredoxin -
  GOM48_RS05405 (GOM48_05425) vicX 1069428..1070237 (-) 810 WP_235096358.1 MBL fold metallo-hydrolase Regulator
  GOM48_RS05410 (GOM48_05430) micB 1070239..1071588 (-) 1350 WP_235096359.1 cell wall metabolism sensor histidine kinase VicK Regulator
  GOM48_RS05415 (GOM48_05435) micA 1071581..1072288 (-) 708 WP_235096360.1 response regulator YycF Regulator
  GOM48_RS05420 (GOM48_05440) mutY 1072345..1073523 (-) 1179 WP_235096361.1 A/G-specific adenine glycosylase -
  GOM48_RS05425 (GOM48_05445) pta 1073612..1074586 (-) 975 WP_000451592.1 phosphate acetyltransferase -
  GOM48_RS05430 (GOM48_05450) - 1074630..1075526 (-) 897 WP_235096362.1 RluA family pseudouridine synthase -
  GOM48_RS05435 (GOM48_05455) - 1075523..1076341 (-) 819 WP_223326689.1 NAD kinase -
  GOM48_RS05440 (GOM48_05460) - 1076325..1076996 (-) 672 WP_000151563.1 GTP pyrophosphokinase family protein -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26979.77 Da        Isoelectric Point: 4.6219

>NTDB_id=404919 GOM48_RS05415 WP_235096360.1 1071581..1072288(-) (micA) [Streptococcus oralis strain SOD]
MKKILVVDDEKPISDIIKFNMAKEGYEVVTAFNGREAIELFEAEQPDIIILDLMLPEIDGLEVAKTIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTDLASADSQESDEKKSQPLQIGDLEILPDAYVAKKYGEELEL
THREFELLYHLASHIGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 708 bp        

>NTDB_id=404919 GOM48_RS05415 WP_235096360.1 1071581..1072288(-) (micA) [Streptococcus oralis strain SOD]
ATGAAAAAAATATTAGTTGTAGATGATGAGAAACCAATCTCAGATATTATTAAGTTCAATATGGCCAAGGAAGGCTATGA
GGTTGTAACAGCCTTTAACGGTAGAGAAGCTATCGAGCTATTTGAGGCGGAGCAACCAGATATTATTATTCTAGACTTGA
TGCTACCTGAAATCGATGGTTTAGAAGTTGCTAAGACCATTCGTAAGACTAGCAGTGTTCCAATCATTATGTTATCAGCC
AAGGATAGTGAGTTTGACAAGGTTATCGGTTTAGAACTTGGGGCAGATGATTATGTGACCAAACCCTTCTCAAATCGTGA
GTTGCAAGCGCGTGTAAAGGCTTTACTCCGCCGTACAGACCTCGCTTCAGCTGATAGTCAAGAGTCTGATGAAAAGAAAT
CCCAACCCCTACAGATTGGCGATTTGGAAATTCTGCCAGACGCTTACGTAGCCAAAAAATATGGTGAGGAATTAGAGTTG
ACTCATCGTGAGTTTGAGCTATTGTACCACTTGGCCTCTCACATTGGTCAAGTCATTACTCGTGAACACTTGCTTGAGAC
TGTTTGGGGCTATGATTATTTTGGTGATGTTCGTACAGTGGACGTGACCATCCGACGTTTGCGTGAAAAAATCGAAGACA
CTCCAAGCCGTCCAGAATACATCCTAACCCGTCGTGGTGTGGGTTACTATATGAGAAATAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

91.026

99.574

0.906
  vicR Streptococcus mutans UA159

77.872

100

0.779
  covR Streptococcus salivarius strain HSISS4

43.59

99.574

0.434
  covR Lactococcus lactis subsp. lactis strain DGCC12653

42.857

98.298

0.421
  scnR Streptococcus mutans UA159

36.481

99.149

0.362

Multiple sequence alignment